Results 11 to 20 of about 6,797,208 (350)

The N-terminal domain of the repressor of Staphylococcus aureus phage Φ11 possesses an unusual dimerization ability and DNA binding affinity. [PDF]

PLoS ONE, 2014
Bacteriophage Φ11 uses Staphylococcus aureus as its host and, like lambdoid phages, harbors three homologous operators in between its two divergently oriented repressor genes. None of the repressors of Φ11, however, showed binding to all three operators,
Anindya Biswas, Sukhendu Mandal, Subrata Sau   +2 more
doaj   +1 more source

Evidence-Based Structural Model of the Staphylococcal Repressor Protein: Separation of Functions into Different Domains. [PDF]

PLoS ONE, 2015
Horizontal transfer of mobile genetic elements within Staphylococci is of high biomedical significance as such elements are frequently responsible for virulence and toxic effects.
Kinga Nyíri, Bianka Kőhegyi, András Micsonai, József Kardos, Beata G Vertessy   +4 more
doaj   +1 more source

Rules of Expansion: an Updated Consensus Operator Site for the CopR-CopY Family of Bacterial Copper Exporter System Repressors

mSphere, 2020
Copper is broadly toxic to bacteria. As such, bacteria have evolved specialized copper export systems (cop operons) often consisting of a DNA-binding/copper-responsive regulator (which can be a repressor or activator), a copper chaperone, and a copper ...
Henrik O’Brien, Joseph W. Alvin, Sanjay V. Menghani, Yamil Sanchez-Rosario, Koenraad Van Doorslaer, Michael D. L. Johnson   +5 more
doaj   +1 more source

Repressor of temperate mycobacteriophage L1 harbors a stable C-terminal domain and binds to different asymmetric operator DNAs with variable affinity

Virology Journal, 2007
Background Lysogenic mode of life cycle of a temperate bacteriophage is generally maintained by a protein called 'repressor'. Repressor proteins of temperate lambdoid phages bind to a few symmetric operator DNAs in order to regulate their gene expression.
Mandal Nitai C, Das Malabika, Chanda Palas K, Chattoraj Partho, Bandhu Amitava, Ganguly Tridib, Sau Subrata   +6 more
doaj   +1 more source

The trans-activation domain of the sporulation response regulator Spo0A revealed by X-ray crystallography [PDF]

, 2000
Sporulation in Bacillus involves the induction of scores of genes in a temporally and spatially co-ordinated programme of cell development. Its initiation is under the control of an expanded two-component signal transduction system termed a phosphorelay.
Baldus J.M., Brown D.P., Buckner C.M., Buckner C.M., Busby S., Chung J.D., Cowtan K., Ferrari F.A., Fogh R.H., Green B.D., Grimsley J.K., Hatt J.K., Igarashi K., Ireton K., Kenney T.J., Kondo H., Kuldell N., Makino K., Martinez-Hackert E., Muchova K., Murshudov G.N., Olmedo G., Perego M., Satola S.W., Schyns G., Spiegelman G.B., Spiegelman G.B., Strauch M.A., Strauch M.A., Terwilliger T.C., Weir J., Wu H.-M., York K.   +32 more
core   +1 more source

BiFCROS: A Low-Background Fluorescence Repressor Operator System for Labeling of Genomic Loci

G3: Genes, Genomes, Genetics, 2017
Fluorescence-based methods are widely used to analyze elementary cell processes such as DNA replication or chromosomal folding and segregation. Labeling DNA with a fluorescent protein allows the visualization of its temporal and spatial organization. One
Sarah Milbredt, Torsten Waldminghaus
doaj   +1 more source

The MarR-Type Repressor MhqR Confers Quinone and Antimicrobial Resistance in Staphylococcus aureus [PDF]

, 2019
Aims: Quinone compounds are electron carriers and have antimicrobial and toxic properties due to their mode of actions as electrophiles and oxidants.
Fritsch, Verena Nadin, Loi, Vu Van, Busche, Tobias, Sommer, Anna, Tedin, Karsten, Nürnberg, Dennis J., Kalinowski, Jörn, Bernhardt, Jörg, Fulde, Marcus, Antelmann, Haike   +9 more
core   +1 more source

KPNB1 mediates PER/CRY nuclear translocation and circadian clock function

eLife, 2015
Regulated nuclear translocation of the PER/CRY repressor complex is critical for negative feedback regulation of the circadian clock of mammals. However, the precise molecular mechanism is not fully understood.
Yool Lee, A Reum Jang, Lauren J Francey, Amita Sehgal, John B Hogenesch   +4 more
doaj   +1 more source

Clearance of an amyloid-like translational repressor is governed by 14-3-3 proteins

Cell Reports, 2022
Summary: Amyloids are fibrous protein aggregates associated with age-related diseases. While these aggregates are typically described as irreversible and pathogenic, some cells use reversible amyloid-like structures that serve important functions.
S. Grace Herod, Annie Dyatel, Stefanie Hodapp, Marko Jovanovic, Luke E. Berchowitz   +4 more
doaj   +1 more source

KRAB-containing zinc-finger repressor proteins

Genome Biology, 2003
SummaryThe largest family of zinc-finger transcription factors comprises those containing the Krüppel-associated box (or KRAB domain), which are present only in tetrapod vertebrates.
R. Urrutia
semanticscholar   +1 more source