Results 21 to 30 of about 6,797,208 (350)

Mobility of the native Bacillus subtilis conjugative plasmid pLS20 is regulated by intercellular signaling.

PLoS Genetics, 2013
Horizontal gene transfer mediated by plasmid conjugation plays a significant role in the evolution of bacterial species, as well as in the dissemination of antibiotic resistance and pathogenicity determinants.
Praveen K Singh, Gayetri Ramachandran, Ricardo Ramos-Ruiz, Ramón Peiró-Pastor, David Abia, Ling J Wu, Wilfried J J Meijer   +6 more
doaj   +1 more source

Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia

Cell Reports, 2021
Summary: Despite absent expression in normal hematopoiesis, the Forkhead factor FOXC1, a critical mesenchymal differentiation regulator, is highly expressed in ∼30% of HOXAhigh acute myeloid leukemia (AML) cases to confer blocked monocyte/macrophage ...
Fabrizio Simeoni, Isabel Romero-Camarero, Francesco Camera, Fabio M.R. Amaral, Oliver J. Sinclair, Evangelia K. Papachristou, Gary J. Spencer, Michael Lie-A-Ling, Georges Lacaud, Daniel H. Wiseman, Jason S. Carroll, Tim C.P. Somervaille   +11 more
doaj   +1 more source

Synthetic biology—putting engineering into biology [PDF]

, 2006
Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core   +1 more source

Genome-Wide Identification, Functional Analysis and Expression Profiling of the Aux/IAA Gene Family in Tomato [PDF]

, 2012
Auxin is a central hormone that exerts pleiotropic effects on plant growth including the development of roots, shoots, flowers and fruit. The perception and signaling of the plant hormone auxin rely on the cooperative action of several components,among
Abel, Abel, Abel, Bargmann, Carole Bassa, Chaabouni, Chaabouni, Corinne Audran-Delalande, Deng, Dharmasiri, Dharmasiri, Dreher, Eshed, Farid Regad, Finn, Hagen, Hamilton, Isabelle Mila, Jain, Jones, Kagale, Kalluri, Kepinski, Kloosterman, Leclercq, Li, Liscum, Mohamed Zouine, Mondher Bouzayen, Montgomery, Nebenführ, Oeller, Ohme-Takagi, Ottenschläger, Overvoorde, Paponov, Pirrello, Reed, Remington, Saitou, Sato, Szemenyei, Tamura, Tan, Theologis, Tiwari, Tiwari, Uehara, Ulmasov, Ulmasov, Wang, Wang, Wang, Wang, Yamamoto, Zuckerkandl   +55 more
core   +4 more sources

Two-Hybrid System for Characterization of Protein-Protein Interactions in E. coli

BioTechniques, 2000
The yeast two-hybrid system has been used to characterize many protein-protein interactions. A two-hybrid system for E. coli was constructed in which one hybrid protein bound to a specific DNA site recruits another to an adjacent DNA binding site.
Lori B. Hays, Yuen-Shing A. Chen, James C. Hu   +2 more
doaj   +1 more source

Bacteriophage crosstalk: coordination of prophage induction by trans-acting antirepressors.

PLoS Genetics, 2011
Many species of bacteria harbor multiple prophages in their genomes. Prophages often carry genes that confer a selective advantage to the bacterium, typically during host colonization.
Sébastien Lemire, Nara Figueroa-Bossi, Lionello Bossi   +2 more
doaj   +1 more source

From DNA sequence to application: possibilities and complications [PDF]

, 1999
The development of sophisticated genetic tools during the past 15 years have facilitated a tremendous increase of fundamental and application-oriented knowledge of lactic acid bacteria (LAB) and their bacteriophages.
A Bruttin, A Bruttin, A Kraus, A Nauta, A Nauta, A Nauta, A Sazicu, AK Aggarwal, B Christiansen, B Christiansen, BC Lokman, BC Lokman, BM Chassy, C Delorme, C Hill, C Schouler, CA Alpert, CA Shearman, CJ Hueck, CO Pabo, CT Verrips, D Botstein, D Lillehaug, D Lillehaug, D Sinderen, DJ O’Sullivan, DJ O’Sullivan, DO Gostick, DO Gostick, E Küster, E Maguin, E Stanley, EJ Luesink, EJ Luesink, EJ Luesink, F Desiere, F Desiere, G Buist, G Buist, G Ramsay, G Vriend, GM Djordjevic, GM Djordjevic, H Brüssow, H Holo, H Neve, I Biswas, J Bardowski, J Bernhardt, J Green, J Law, J Payne, J Stülke, JB Luchansky, JD Boyce, JW Sanders, JW Sanders, JW Sanders, K Chung, K Leenhouts, K Leenhouts, K Leenhouts, K Schnetz, KI Kodaira, KJ Leenhouts, L Dupont, L Dupont, LJ Beamer, LR Garcia, M Curie, M de Guchte, M de Guchte, M Lieb, M Ptashne, MG Johnsen, MJ Gasson, MJ Weickert, MM Sheehan, MW Lubbers, MW Lubbers, N Goupil-Feuillerat, OP Kuipers, P Hals, PG Ruyter, PGGA Ruyter, PL Madsen, PS Chandry, R Parreira, R Schmid, R Young, R Young, RR Raya, S Challou, S Lucchini, S Lucchini, S Simonen, S Spiro, S Spiro, SA Walker, SB Mclvilc, SG Kim, SM Heller, SM Madsen, SR Swindell, T Sasaki, TM Ramseier, V Vagner, WM Vos, WM Vos, WM Vos, Y Fujita   +110 more
core   +3 more sources

Spatial epigenetic control of mono- and bistable gene expression. [PDF]

PLoS Biology, 2010
Bistability in signaling networks is frequently employed to promote stochastic switch-like transitions between cellular differentiation states. Differentiation can also be triggered by antagonism of activators and repressors mediated by epigenetic ...
János Z Kelemen, Prasuna Ratna, Simone Scherrer, Attila Becskei   +3 more
doaj   +1 more source

Isolating intrinsic noise sources in a stochastic genetic switch [PDF]

, 2011
The stochastic mutual repressor model is analysed using perturbation methods. This simple model of a gene circuit consists of two genes and three promotor states. Either of the two protein products can dimerize, forming a repressor molecule that binds to
Newby, J. M.
core   +2 more sources

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors [PDF]

Biochemical Journal, 2008
The PRH (proline-rich homeodomain) [also known as Hex (haematopoietically expressed homeobox)] protein is a transcription factor that functions as an important regulator of vertebrate development and many other processes in the adult including haematopoiesis.
Desjobert, C, Noy, P, Swingler, T, Williams, H, Gaston, K, Jayaraman, P-S   +5 more
openaire   +5 more sources