Results 21 to 30 of about 188,329 (316)

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors [PDF]

open access: yesBiochemical Journal, 2008
The PRH (proline-rich homeodomain) [also known as Hex (haematopoietically expressed homeobox)] protein is a transcription factor that functions as an important regulator of vertebrate development and many other processes in the adult including haematopoiesis.
Desjobert, C   +5 more
openaire   +5 more sources

Spatial epigenetic control of mono- and bistable gene expression. [PDF]

open access: yesPLoS Biology, 2010
Bistability in signaling networks is frequently employed to promote stochastic switch-like transitions between cellular differentiation states. Differentiation can also be triggered by antagonism of activators and repressors mediated by epigenetic ...
János Z Kelemen   +3 more
doaj   +1 more source

The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor.

open access: yesPLoS ONE, 2014
Jasmonate (JA) signalling is mediated by the JASMONATE-ZIM DOMAIN (JAZ) repressor proteins, which are degraded upon JA perception to release downstream responses. The ZIM protein domain is characteristic of the larger TIFY protein family. It is currently
Amparo Cuéllar Pérez   +10 more
doaj   +1 more source

Modular Organization of the Phd Repressor/Antitoxin Protein [PDF]

open access: yesJournal of Bacteriology, 2004
ABSTRACT The P1 plasmid addiction operon is a compact genetic structure consisting of promoter, operator, antitoxin gene ( phd ), and toxin gene ( doc ). The 73-amino-acid antitoxin protein, Phd, has two distinct functions: it represses transcription (by binding to its operator) and
Jeremy Allen, Smith, Roy David, Magnuson
openaire   +2 more sources

The Bacteriophage–Phage-Inducible Chromosomal Island Arms Race Designs an Interkingdom Inhibitor of dUTPases

open access: yesMicrobiology Spectrum, 2023
Stl, the master repressor of the Staphylococcus aureus pathogenicity islands (SaPIs), targets phage-encoded proteins to derepress and synchronize the SaPI and the helper phage life cycles. To activate their cycle, some SaPI Stls target both phage dimeric
Carla Sanz-Frasquet   +4 more
doaj   +1 more source

I. Biosynthesis of a Repressor/Nuclease Hybrid Protein

open access: yesJournal of Biological Chemistry, 1989
The phage T7 endonuclease gene was fused to the 3' end of the lac repressor gene. The hybrid protein exhibits repressor and nuclease functions in a manner dependent on the conformation of the DNA. With supercoiled DNA, nuclease activity is directed to the major cruciform, whereas with linear DNA, the enzyme cleaves preferentially restriction fragments ...
N, Panayotatos, A, Fontaine, S, Bãckman
openaire   +2 more sources

Myb‐like transcription factors have epistatic effects on circadian clock function but additive effects on plant growth

open access: yesPlant Direct, 2023
The functions of closely related Myb‐like repressor and Myb‐like activator proteins within the plant circadian oscillator have been well‐studied as separate groups, but the genetic interactions between them are less clear.
Cassandra L. Hughes, Stacey L. Harmer
doaj   +1 more source

A Repressor Protein Complex Regulates Leaf Growth in Arabidopsis [PDF]

open access: yesThe Plant Cell, 2015
Cell number is an important determinant of final organ size. In the leaf, a large proportion of cells are derived from the stomatal lineage. Meristemoids, which are stem cell-like precursor cells, undergo asymmetric divisions, generating several pavement cells adjacent to the two guard cells.
Nathalie Gonzalez   +17 more
openaire   +3 more sources

Direct observation of dimerization between different CREB1 isoforms in a living cell. [PDF]

open access: yesPLoS ONE, 2011
Cyclic AMP-responsive element binding protein 1 (CREB1) plays multiple functions as a transcription factor in gene regulation. CREB1 proteins are also known to be expressed in several spliced isoforms that act as transcriptional activators or repressors.
Hisayo Sadamoto   +4 more
doaj   +1 more source

Characterization of the Radiation Desiccation Response Regulon of the Radioresistant Bacterium Deinococcus radiodurans by Integrative Genomic Analyses

open access: yesCells, 2021
Numerous genes are overexpressed in the radioresistant bacterium Deinococcus radiodurans after exposure to radiation or prolonged desiccation. It was shown that the DdrO and IrrE proteins play a major role in regulating the expression of approximately ...
Nicolas Eugénie   +7 more
doaj   +1 more source

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