Regulation of Synaptic Pumilio Function by an Aggregation-Prone Domain [PDF]
We identified Pumilio (Pum), a Drosophila translational repressor, in a computational search for metazoan proteins whose activities might be regulated by assembly into ordered aggregates.
Menon, Kaushiki P. +3 more
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The non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor.
Jasmonate (JA) signalling is mediated by the JASMONATE-ZIM DOMAIN (JAZ) repressor proteins, which are degraded upon JA perception to release downstream responses. The ZIM protein domain is characteristic of the larger TIFY protein family. It is currently
Amparo Cuéllar Pérez +10 more
doaj +1 more source
A dominant repressor version of the tomatoSl-ERF.B3gene confers ethylene hypersensitivity via feedback regulation of ethylene signaling and response components [PDF]
Ethylene Response Factors (ERFs) are downstream components of the ethylene signal transduction pathway, although their role in ethylene-dependent developmental processes remains poorly understood. As the ethylene-inducible tomato Sl-ERF.B3 has been shown
Achard +51 more
core +4 more sources
Optimizing periodicity and polymodality in noise-induced genetic oscillators [PDF]
Many cellular functions are based on the rhythmic organization of biological processes into self-repeating cascades of events. Some of these periodic processes, such as the cell cycles of several species, exhibit conspicuous irregularities in the form of
A. Sveiczer +6 more
core +3 more sources
Modular Organization of the Phd Repressor/Antitoxin Protein [PDF]
ABSTRACT The P1 plasmid addiction operon is a compact genetic structure consisting of promoter, operator, antitoxin gene ( phd ), and toxin gene ( doc ). The 73-amino-acid antitoxin protein, Phd, has two distinct functions: it represses transcription (by binding to its operator) and
Jeremy Allen, Smith, Roy David, Magnuson
openaire +2 more sources
Stl, the master repressor of the Staphylococcus aureus pathogenicity islands (SaPIs), targets phage-encoded proteins to derepress and synchronize the SaPI and the helper phage life cycles. To activate their cycle, some SaPI Stls target both phage dimeric
Carla Sanz-Frasquet +4 more
doaj +1 more source
What makes the lac-pathway switch: identifying the fluctuations that trigger phenotype switching in gene regulatory systems [PDF]
Multistable gene regulatory systems sustain different levels of gene expression under identical external conditions. Such multistability is used to encode phenotypic states in processes including nutrient uptake and persistence in bacteria, fate ...
Berg, Johannes +3 more
core +2 more sources
I. Biosynthesis of a Repressor/Nuclease Hybrid Protein
The phage T7 endonuclease gene was fused to the 3' end of the lac repressor gene. The hybrid protein exhibits repressor and nuclease functions in a manner dependent on the conformation of the DNA. With supercoiled DNA, nuclease activity is directed to the major cruciform, whereas with linear DNA, the enzyme cleaves preferentially restriction fragments ...
N, Panayotatos, A, Fontaine, S, Bãckman
openaire +2 more sources
ArgR is an essential local transcriptional regulator of the arcABC-operon in Streptococcus suis and crucial for biological fitness in acidic environment [PDF]
Streptococcus suis is one of the most important pathogens in pigs and can also cause severe infections in humans. Despite its clinical relevance very little is known about the factors contributing to its virulence.
Benga, L. +6 more
core +2 more sources
The functions of closely related Myb‐like repressor and Myb‐like activator proteins within the plant circadian oscillator have been well‐studied as separate groups, but the genetic interactions between them are less clear.
Cassandra L. Hughes, Stacey L. Harmer
doaj +1 more source

