Results 51 to 60 of about 90,613,697 (136)

Triiodothyroacetic acid exerts tissue-specific thyromimetic effects without tachycardia and hyperthermia in male mice

open access: yesEuropean Thyroid Journal
Objective: Thyroid hormones regulate cardiovascular functions and energy homeostasis, including thermogenesis, through binding to nuclear thyroid hormone receptors. The thyroid hormone analog 3,3′,5-triiodothyroacetic acid (TRIAC) has recently emerged as
Beate Herrmann   +3 more
doaj   +1 more source

Resistance to thyroid hormone beta (R243Q) with autoimmune primary hypothyroidism: report of a kindred [PDF]

open access: yesArchives of Endocrinology and Metabolism
The syndrome of resistance to thyroid hormone beta (RTHβ) is characterized by impaired tissue responsiveness to thyroid hormone and manifests as non-suppressed thyrotropin despite elevated thyroid hormone levels.
Alpesh Goyal, Rahul Gupta, Rekha Singh
doaj   +1 more source

Mutational Landscape of Resistance to Thyroid Hormone Beta (RTHβ)

open access: yes, 2019
Resistance to thyroid hormone beta (RTHβ) is a syndrome characterized by reduced responsiveness of peripheral tissues to thyroid hormone (TH). In most cases, the disorder is associated with germline pathogenic variants in the thyroid hormone receptor ...
Paragliola R. M.
core   +1 more source

A Case of Resistance to Thyroid Hormone with Chronic Thyroiditis: Discovery of a Novel Mutation (I54V)

open access: yesCase Reports in Endocrinology, 2011
Resistance to thyroid hormone (RTH) is a rare disorder characterized by variable tissue hyporesponsiveness to thyroid hormone, usually caused by mutations in the thyroid hormone receptor beta (TRβ).
I. Kammoun   +5 more
doaj   +1 more source

A Novel Thyroid Hormone Receptor Beta Mutation (G357R) in a Family with Resistance to Thyroid Hormone Beta: Extending the Borders of the "Hot" Region in the THRB Gene

open access: yes, 2019
Resistance to thyroid hormone beta (RTHβ) is a syndrome characterized by high serum levels of thyroid hormone and unsuppressed serum thyrotropin concentrations.
Ferrara, Alfonso Massimiliano   +5 more
core   +1 more source

Clinical and metabolic links between hypothyroidism and metabolic syndrome: a review

open access: yesFrontiers in Endocrinology
Hypothyroidism and metabolic syndrome frequently coexist and share abnormalities in body weight, lipid metabolism, glucose regulation, and inflammatory signaling.
Mubai Li   +6 more
doaj   +1 more source

Effect of thyroid hormone on growth. Lessons from the syndrome of resistance to thyroid hormone

open access: yes, 1996
Thyroid hormone deprivation results in deleterious effects on bone growth. The delayed bone development is mediated by a direct effect of thyroid hormone on bone and an indirect effect of the hormone on GH release and IGF-1 action.
Weiss, R E, Refetoff, S
core   +1 more source

Does insulin resistance increase thyroid volume in patients with polycystic ovary syndrome?

open access: yesArchives of Endocrinology and Metabolism
Objective To investigate the effect of gonadotropin, sex hormone levels and insulin resistance (IR) on thyroid functions and thyroid volume (TV) in polycystic ovary syndrome (PCOS). Subjects and methods 69 new diagnosed PCOS patients (age 24.82 ± 6.17)
Murat Sahin   +6 more
doaj   +1 more source

Thyrotropin-producing adenoma: diagnostic challenges (Сase report)

open access: yesКлиническая и экспериментальная тиреоидология, 2011
Pituitary thyrotropin-producing adenomas (TSH-omas) are rare tumors that cause hyperthyroidism. Failure to recognize this disease may result in dramatic consequences, such as improper thyroid ablation in patients with central hyperthyroidism.

doaj   +1 more source

Thyroid Hormone Resistance Syndrome: A Case Report with Literature Review [PDF]

open access: yes
Resistance to thyroid hormone receptor beta (THRβ) is a rare condition causing abnormal thyroid function tests (TFTs) characterized by elevated thyroid hormone levels with unsuppressed Thyroid Stimulating Hormone (TSH).
Ahmed, Nourhan   +4 more
core   +1 more source

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