Results 41 to 50 of about 90,613,697 (136)

Mosaicism of a thyroid hormone receptor-beta gene mutation in resistance to thyroid hormone

, 2006
Context: Heterozygous mutations in thyroid hormone receptor-beta (TR beta) gene are the cause of resistance to thyroid hormone (RTH) in more than 85% of families having the syndrome. In 23% of the families, TR beta gene mutations occur de novo.
Liao, Xiao-Hui, Mamanasiri, Sunee, Demir, TEVFİK, Yesil, Sena, Dumitrescu, Alexandra M., Weiss, Roy E, Weiss, Roy E., Dumitrescu, Alexandra M, Refetoff, Samuel   +8 more
core   +1 more source

Thyroid-like function in the urochordate Ciona intestinalis [PDF]

, 2011
In the studies reported in the manuscript I investigated the involvement of Iodine and thyroxine (Thyroid Hormone, T4) in Ciona intestinalis metamorphosis. To date, the mechanisms regulating the metamorphosis of ascidians remain largely unknown.
Staiano, Leopoldo
core   +1 more source

Syndromes of resistance to thyroid hormone

Clinical and experimental thyroidology, 2013
Синдром резистентности к тиреоидным гормо нам (RTH) является наследственным синдромом, характеризующимся пониженной чувствительнос тью тканеймишеней к гормонам щитовидной желе зы. RTH впервые был описан в 1967 году как часть семейного синдрома, включающего глухонемоту, зоб и аномально повышенный уровень тиреоидных гор монов на фоне нормальной ...
V A Kaldymova, A V Kiyaev, A N Tyulpakov
openaire   +2 more sources

Sensitivity to thyroid hormones in Egyptian euthyroid patients with metabolic syndrome

The Egyptian Journal of Internal Medicine
Background Metabolic syndrome (MetS) is a common metabolic and endocrine disease, and many studies have found that thyroid disorders, both overt and subclinical, might be accompanied by the risk of MetS. Objectives Assessment of indices of sensitivity to
Heba Ibrahim Selim, Fayez Elkenawy Mohammad, Mohammed Ibrahim Abd El-Ghany   +2 more
doaj   +1 more source

Clinical Characteristics and Genotype-phenotype Correlation in Turkish Patients with a Diagnosis of Resistance to Thyroid Hormone Beta [PDF]

Objective: Resistance to thyroid hormone beta (RTHβ) is a rare disorder characterized by a fairly heterogeneous clinical presentation due to varying degrees of tissue response to thyroid hormone.
Çavdarlı, Büşranur, Mehmet Boyraz, Boyraz, Mehmet, Büşranur Çavdarlı, Nur Semerci Gündüz, cakal, erman, Oya Topaloğlu, Gündüz, C.Nur Semerci, Sema Hepşen, Demirbilek, Huseyin, Erman Çakal, gürbüz, fatih, Aydın, Cevdet, Koca, Serkan bilge, Keziban Toksoy Adıgüzel, topaloglu, oya, Cevdet Aydın, Fatih Gürbüz, Hüseyin Demirbilek, Serkan Bilge Koca, HEPŞEN, SEMA, Toksoy, Keziban, Buyukyilmaz, Gonul, Gönül Büyükyılmaz, Semerci Gündüz, Nur, Büyükyılmaz, GÖNÜL, Toksoy Adıgüzel, Keziban   +26 more
core   +1 more source

Extreme resistance to thyroid hormone caused by a novel mosaic thyroid hormone receptor beta mutation

European Thyroid Journal
Background: Patients with resistance to thyroid hormone β (RTHβ) show elevated thyroid hormone concentrations with non-suppressed thyroid-stimulating hormone (TSH) concentrations and large phenotypic variability.
Ferdy S van Geest, Wenjun Liao, Paul G Voorhoeve, Willemijn G Leen, Nitash Zwaveling-Soonawala, V Krishna Chatterjee, Sjoerd A A Van den Berg, Frederik A Verburg, Marcel E Meima, Erica L T van den Akker, W Edward Visser   +10 more
doaj   +1 more source

Correlation between the thyrotropin-thyroxine resistance index and insulin resistance in polycystic ovary syndrome patients with phlegm-dampness syndrome

Frontiers in Endocrinology
IntroductionPolycystic ovary syndrome (PCOS) patients classified as the phlegm-dampness syndrome typically suffer from metabolic dysfunction mainly driven by insulin resistance (IR).
Ying Liu, Ming Zhang, Ying Wang, Xueyan Lv, Shuang Ma, Jinglu Yu, Hongying Kuang, Lihui Hou, Qingxia Song   +8 more
doaj   +1 more source

Thyroid hormone resistance syndrome – own experiences

Pediatric Endocrinology Diabetes and Metabolism, 2017
Thyroid hormone resistance syndrome, also known as Refetoff syndrome, is a rare disease associated with decreased reaction of body tissues to thyroid hormones (TH). Patients with Refetoff syndrome tend to have elevated free TH concentrations and normal or inadequately elevated TSH (caused by thyrotropic cells in the pituitary gland insensitivity to TH).
Tomasz, Jackowski, Elżbieta, Petriczko, Anita, Horodnicka-Józwa, Mieczysław, Walczak   +3 more
openaire   +2 more sources

Audiological alterations in resistance to thyroid hormone syndrome: emphasizing lifelong assessment [PDF]

Archives of Endocrinology and Metabolism
The aim of this study was to investigate the long-term audiological consequences of resistance to thyroid hormone (RTH) syndrome. The cochlea and inner ear express thyroid hormone receptor beta (THRB) in developmental stages.
Alexandre Machado Silva de Oliveira, Viviane Motti, Jessica Casemiro, Pedro Resende Rende, Caio Leônidas Oliveira de Andrade, Luciene da Cruz Fernande, Helton Estrela Ramos   +6 more
doaj   +1 more source

Is There an Association between Thyroid Disease and Metabolic Syndrome [PDF]

Zagazig University Medical Journal
Background: The metabolic syndrome and thyroid dysfunctions are the two most prevalent endocrine illnesses, and they significantly overlap. Due to their strong associations with morbidity and mortality, both have a huge global influence on health care ...
Nermin Ghanem, Moanes Enaba, Hatem Salem, AHMED SAEID   +3 more
doaj   +1 more source