Results 71 to 80 of about 54,681 (257)

Occlusion of retinal capillaries caused by glial cell proliferation in chronic ocular inflammation [PDF]

open access: yes, 2015
The inner blood-retinal barrier is a gliovascular unit in which glial cells surround capillary endothelial cells and regulate retinal capillaries by paracrine interactions.
Artico, Marco   +8 more
core   +2 more sources

ABCF1 extrinsically regulates retinal pigment epithelial cell phagocytosis

open access: yesMolecular Biology of the Cell, 2015
Phagocytosis of shed photoreceptor outer segments (POSs) by retinal pigment epithelial (RPE) cells is critical to retinal homeostasis and shares many conserved signaling pathways with other phagocytes, including extrinsic regulations. Phagocytotic ligands are the key to cargo recognition, engulfment initiation, and activity regulation.
Guo, Feiye   +6 more
openaire   +3 more sources

Therapeutic Gases in Biomedicine: Updates on Nitric Oxide and Beyond

open access: yesAdvanced Science, EarlyView.
Therapeutic gases, including NO, CO, H2S, H2, CO2, O2, and Xe, play vital roles in cellular signaling and repair. This review highlights the emerging carriers and delivery systems that enable controlled, localized gas release for diagnostic and therapeutic applications.
Syed Muntazir Andrabi   +4 more
wiley   +1 more source

Novel RGD-lipid conjugate-modified liposomes for enhancing siRNA delivery in human retinal pigment epithelial cells

open access: yesInternational Journal of Nanomedicine, 2011
Cheng-Wei Chen1, Da-Wen Lu2, Ming-Kung Yeh3, Chia-Yang Shiau4, Chiao-Hsi Chiang1,5 1Graduate Institute of Life Sciences, 2Department of Ophthalmology, Tri-Service General Hospital, 3Institution of Preventive Medicine, 4Graduate Institute of Medical ...
Chen CW   +4 more
doaj  

Quantified F-Actin Morphology Is Predictive of Phagocytic Capacity of Stem Cell-Derived Retinal Pigment Epithelium

open access: yesStem Cell Reports, 2018
Summary: With stem cell-derived retinal pigment epithelial (RPE) replacement therapies in clinical testing, establishing potency of RPE prior to transplantation is imperative. Phagocytosis of photoreceptor outer segment fragments (POS) is a key indicator
Claudia Müller   +3 more
doaj   +1 more source

FLII and MLL1 Cooperatively Regulate Aryl Hydrocarbon Receptor-Mediated Transcription in ARPE-19 Cells

open access: yesCurrent Issues in Molecular Biology, 2021
Aryl hydrocarbon receptors (AHRs), a class of ligand-dependent nuclear receptors that regulate cellular responses by inducing the expression of various target genes in response to external signals, are implicated in maintaining retinal tissue homeostasis.
Kwang Won Jeong
doaj   +1 more source

Bucky Paper as a Support Membrane in Retinal Cell Transplantation [PDF]

open access: yes, 2006
A method for repairing a retinal system of an eye, using bucky paper on which a plurality of retina pigment epithelial cells and/or iris pigment epithelial cells and/or stem cells is deposited, either randomly or in a selected cell pattern.
Fishman, Harvey   +3 more
core   +1 more source

TALEN-mediated apc mutation in Xenopus tropicalis phenocopies familial adenomatous polyposis [PDF]

open access: yes, 2015
Truncating mutations in the tumor suppressor gene adenomatous polyposis coli (APC) are the initiating step in the vast majority of sporadic colorectal cancers, and they underlie familial adenomatous polyposis (FAP) syndromes.
Creytens, David   +8 more
core   +3 more sources

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

open access: yesAdvanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale   +6 more
wiley   +1 more source

Exposure to the complement C5b-9 complex sensitizes 661W photoreceptor cells to both apoptosis and necroptosis. [PDF]

open access: yes, 2015
The loss of photoreceptors is the defining characteristic of many retinal degenerative diseases, but the mechanisms that regulate photoreceptor cell death are not fully understood.
Francesca Cordeiro, M   +5 more
core   +1 more source

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