Results 101 to 110 of about 86,354 (308)

Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities

, 2009
Vitamin A is a nutrient with remarkable effects on adipose tissue and skeletal muscles and plays a role in controlling energy balance. Retinoic acid (RA), the carboxylic form of vitamin A, has been associated with improved glucose tolerance and insulin ...
Aubry, Evelyne M, Odermatt, A., Aubry, E. M., Odermatt, Alex   +3 more
core   +1 more source

Essential embryology for the Canadian pathologists’ assistant

Anatomical Sciences Education, EarlyView.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci, William Tsui, Fang‐I Lu, Avrum I. Gotlieb, Danielle C. Bentley   +4 more
wiley   +1 more source

Neuronal differentiation and tissue engineering strategies for central neurous system injury repair

BMEMat, EarlyView.
This review outlines tissue engineering advances for central nervous system (CNS) injury treatment, focusing on three core components: seed cells, inductive factors, and scaffold materials, with evaluation of their respective strengths and limitations. Tissue engineering for CNS injury repair.
Zhuqing Xia, Jinghui Zhang, Na Ren, Shuping Wang, Congcong Zhang, Nik Ahmad Nizam Nik Malek, Wan Hairul Anuar Kamaruddin, Chao Liu, Chunhui Sun, Jingang Wang   +9 more
wiley   +1 more source

Differential effects of retinoic acid isomers on the expression of nuclear receptor co-regulators in neuroblastoma

, 1999
Retinoic acid modulates growth and induces differentiation and apoptosis of neuroblastoma cells in vitro, with the all-trans and 9-cis isomers having different biological properties.
Pearson AD, Dobson MG, CORAZZARI, MARCO, Annicchiarico Petruzzelli M, Redfern CP, Lovat PE, Melino G, Malcolm AJ   +7 more
core   +3 more sources

Retinobenzoic Acids and Nuclear Retinoic Acid Receptors.

Cell Structure and Function, 1991
Retinoids (retinoic acid and its analogs) are widely involved in the control of cell proliferation, cell differentiation and embryonic development. A series of potent and novel synthetic retinoids named retinobenzoic acids has been developed. Retinobenzoic acids have proven to be useful tools in the investigation of the molecular mechanisms of ...
openaire   +3 more sources

The biological activity of retinoids in melanoma cells Induction of expression of retinoic acid receptor-β by retinoic acid in S91 melanoma cells

, 1990
The expression of mRNA for retinoic acid receptor beta (RAR-β was induced by all trans-retinoic acid in murine S91 melanoma cells. The induction of RAR-β was dose-dependent, rapid and insensitive to cycloheximide.
Christopher F.F. Redfern, Latham, Julie A.E., Daly, Ann K., Redfern, Christopher F.F., Todd, Carole, Carole Todd, Ann K. Daly, Julie A.E. Latham   +7 more
core   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Pharmacological inhibition of frizzled 4 delays cell cycle progression and limits oral squamous cell carcinoma growth

Frontiers in Cell and Developmental Biology
Oral squamous cell carcinoma is an aggressive malignancy driven by aberrant signaling pathways, with Wnt signaling acting as a central regulator of proliferation, tumor-microenvironment interactions, and oncogenic growth.
Riccardo Destefani, Ilaria J. Valookkaran, Sabrina Bensland, Christian T. Meisel, Cristina Porcheri   +4 more
doaj   +1 more source

Neuromodulation: Actions of Dopamine, Retinoic Acid, Nitric Oxide, and Other Substances on Retinal Horizontal Cells

, 2023
Douglas G McMahon,1 John E Dowling2 1Department of Biological Sciences, Vanderbilt University, Nashville, TN, 37235, USA; 2Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138, USACorrespondence: Douglas G McMahon ...
Dowling JE, McMahon DG
core  

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source