Results 101 to 110 of about 3,704,275 (297)
The role of Rho GTPases in facial morphogenesis
Developmental Dynamics, EarlyView.The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley +1 more source
Developmental Dynamics, EarlyView.Abstract Background The zebrafish heart regenerates upon injury. During injury response, fibroblasts and endothelial cells accumulate at the site of damage, and cardiomyocyte cell cycle reentry allows cardiac muscle regrowth. It is relevant to understand how the different cell types communicate with each other to coordinate regeneration.
João A. S. Carvalho +6 more
wiley +1 more source
Transcriptome analysis of Xenopus orofacial tissues deficient in retinoic acid receptor function
BMC Genomics, 2018 Background Development of the face and mouth is orchestrated by a large number of transcription factors, signaling pathways and epigenetic regulators.
Stacey E. Wahl +3 more
doaj +1 more source
Identification of a Retinoic Acid Receptor α Subtype Specific Agonist
, 2016 Identification of a Retinoic Acid Receptor α Subtype Specific ...
Elliott S. Klein (3018990) +4 more
core +1 more source
Developmental Dynamics, EarlyView.Abstract Neural crest cells are multipotent, migratory stem‐like cells essential for vertebrate development that contribute broadly to many tissues including the craniofacial skeleton, peripheral nervous system, and pigment‐producing cells. Their development progresses through phases of induction, specification, delamination, migration, and ...
Allison E. Mancini +2 more
wiley +1 more source
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Epilepsia Open, EarlyView.Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola +3 more
wiley +1 more source
Discovery of new therapeutic targets in Neuroblastoma by means of proteomic approach and functional studies [PDF]
, 2010 Neuroblatoma (NB) is an embryonal tumor of the sympathetic nervous system which arises from the neural crest cells. This disease rappresents the most common extracranial tumor in infants, accounting for 8% to 10% of all childhood cancer and for ...
Cimmino, Flora
core +1 more source
Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities [PDF]
, 2009 Vitamin A is a nutrient with remarkable effects on adipose tissue and skeletal muscles and plays a role in controlling energy balance. Retinoic acid (RA), the carboxylic form of vitamin A, has been associated with improved glucose tolerance and insulin ...
Aubry, Evelyne M +3 more
core +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Equine Veterinary Journal, EarlyView.Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
, 1990 International audienceAll-trans retinoic acid (RA), the active metabolite of vitamin A, has recently been demonstrated to be an efficient alternative to chemotherapy in the treatment of acute promyelocytic leukemia (M3 subtype of the French-American ...
Ballerini, P +10 more
core +2 more sources