Results 241 to 250 of about 357,868 (360)

Herpes simplex virus‐1 infection alters microtubule‐associated protein Tau splicing and promotes Tau pathology in neural models of Alzheimer's disease

open access: yesBrain Pathology, EarlyView.
HSV‐1 infection alters MAPT splicing and promotes Tau pathology in neural models of Alzheimer's disease. HSV‐1 infection in brain organoids and neuronal models increase 4R‐MAPT splicing and Tau hyperphosphorylation. HSV‐1 ICP27 is both necessary and sufficient for inducing these changes highlighting the potential role of HSV‐1 in Alzheimer's disease ...
Emmanuel C. Ijezie   +9 more
wiley   +1 more source

Adipocyte retinoic acid receptor α prevents obesity and steatohepatitis by regulating energy expenditure and lipogenesis. [PDF]

open access: yesObesity (Silver Spring)
Cassim Bawa FN   +9 more
europepmc   +1 more source

A regulatory circuit controlled by extranuclear and nuclear retinoic acid receptor α determines T cell activation and function. [PDF]

open access: yesImmunity, 2023
Larange A   +18 more
europepmc   +1 more source

Contributions of synaptic energetic dysfunction by microtubule dynamics and microtubule‐based mitochondrial transport disorder to morphine tolerance

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Morphine is among the most powerful analgesic, but its long‐term use can cause tolerance. Synaptic ATP supply is critical for maintaining synaptic transmission. Microtubule‐based mitochondrial transport ensures synaptic energy supply.
Zheng Li   +9 more
wiley   +1 more source

4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.

open access: green, 1996
C C Achkar   +10 more
openalex   +1 more source

In vitro transcription and translation inhibition by anti-promyelocytic leukemia (PML)/retinoic acid receptor alpha and anti-PML peptide nucleic acid [PDF]

open access: bronze, 1996
Carlo Gambacorti‐Passerini   +6 more
openalex   +1 more source

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