Results 231 to 240 of about 79,879 (264)
Some of the next articles are maybe not open access.
Nouvelle revue francaise d'hematologie, 1990
Three retinoic acid receptors (RAR), structurally homologous to steroid and thyroid hormone nuclear receptors, have recently been cloned. Analysis of the tissue distribution of RARs mRNAs have demonstrated a distinct expression pattern of the receptors' transcripts. Moreover, the RAR beta gene specifically, is autoregulated by RA.
H, de Thé, P, Tiollais, A, Dejean
openaire +1 more source
Three retinoic acid receptors (RAR), structurally homologous to steroid and thyroid hormone nuclear receptors, have recently been cloned. Analysis of the tissue distribution of RARs mRNAs have demonstrated a distinct expression pattern of the receptors' transcripts. Moreover, the RAR beta gene specifically, is autoregulated by RA.
H, de Thé, P, Tiollais, A, Dejean
openaire +1 more source
Retinoic Acid Receptor Alpha Amplifications and Retinoic Acid Sensitivity in Breast Cancers
Clinical Breast Cancer, 2013Molecular segmentation of breast cancer allows identification of small groups of patients who present high sensitivity to targeted agents. A patient, with chemo- and trastuzumab-resistant HER2-overexpressing breast cancer, who presented concomitant acute promyelocytic leukemia, showed a response in her breast lesions to retinoic acid, arsenic, and ...
S. Alsafadi +13 more
openaire +3 more sources
Nuclear retinoic acid receptors: Conductors of the retinoic acid symphony during development
Molecular and Cellular Endocrinology, 2012The vitamin A derivative, retinoic acid (RA), is essential for embryonic development through the activation of cognate nuclear receptors, RARs, which work as ligand dependent regulators of transcription. In vitro studies revealed how RARs control gene expression at the molecular level and now it appears that it is fine-tuned by a phosphorylation code ...
Samarut, Eric, Rochette-Egly, Cécile
openaire +3 more sources
Retinoic acid receptors, hematopoiesis and leukemogenesis
Current Opinion in Hematology, 2008All-trans retinoic acid therapy of acute promyelocytic leukemia represents the most successful example of differentiation-induction therapy in clinical oncology. However, acute promyelocytic leukemia represents only a small minority (10-15%) of the myeloid leukemias.
openaire +2 more sources
Mechanisms of transactivation by retinoic acid receptors
BioEssays, 1993AbstractRetinoids play an important role in development and differentiation(1,2). Their effect is mediated through nuclear receptors, RAR (α, β and γ) and RXR (α, β and γ),Abbreviations. RAR: retinoic acid receptor; RXR: retinoid X receptor; T3:thyroid hormone receptor; VD3R: vitamin D3 receptor; PPAR: peroxisome proliferator activated receptor; EcR ...
openaire +2 more sources
MTHFD1 is critical for the negative regulation of retinoic acid receptor signalling in anencephaly
Brain, 2023Shaoyan Chang, Yihua Bao, Xiaolu Xie
exaly
Is 9-Cis-Retinoic Acid the Endogenous Ligand for the Retinoic Acid-X Receptor?
Nutrition Reviews, 2006George Wolf, Wolf George
exaly