Results 241 to 250 of about 3,704,275 (297)

Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells.

Cancer Cell
Colucci M, Zumerle S, Bressan S, Gianfanti F, Troiani M, Valdata A, D'Ambrosio M, Pasquini E, Varesi A, Cogo F, Mosole S, Dongilli C, Desbats MA, Contu L, Revankdar A, Chen J, Kalathur M, Perciato ML, Basilotta R, Endre L, Schauer S, Othman A, Guccini I, Saponaro M, Maraccani L, Bancaro N, Lai P, Liu L, Pernigoni N, Mele F, Merler S, Trotman LC, Guarda G, Calì B, Montopoli M, Alimonti A.   +35 more
europepmc   +1 more source

Mouse and human retinoic acid receptor β2 promoters: sequence comparison and localization of retinoic acid responsiveness

DNA Sequence, 1991
The retinoic acid receptor β (RARβ gene is a member of the family of retinoic acid/thyroid hormone receptor genes, encoding retinoic acid-inducible transcription factors. To study regulation of the RARβ gene, genomic clones containing the mouse and human
Sanbing Shen, Wiebe Kruijer, Paul T van der Saag   +2 more
exaly   +2 more sources

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Retinoic acid and retinoic acid receptors in development

Molecular Neurobiology, 1995
The vitamin A derivative retinoic acid (RA) and related compounds (retinoids) are utilized as signaling molecules in a diverse array of developmental and physiological regulatory processes, including many important in the developing and mature nervous system. Retinoids function by interaction with high affinity receptors of the nuclear receptor family,
H M, Sucov, R M, Evans
openaire   +2 more sources

Retinoic acid and retinoic acid receptors in craniofacial development

Seminars in Cell & Developmental Biology, 1997
Interest in retinoids and craniofacial development originated independently from nutritional and teratological studies; however, the site of action of retinoids in normal development remains contentious. Recent transgenic strategies have shown that retinoic acid and nuclear retinoid receptors are required for the morphogenetic specification of cranial ...
P, Brickell, P, Thorogood
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RETINOIC ACID RECEPTORS AND CANCERS

Annual Review of Nutrition, 2004
▪ Abstract  Studies utilizing experimental animals, epidemiological approaches, cellular models, and clinical trials all provide evidence that retinoic acid and some of its synthetic derivatives (retinoids) are useful pharmacological agents in cancer therapy and prevention.
Dianne Robert, Soprano, Pu, Qin, Kenneth J, Soprano   +2 more
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History of Retinoic Acid Receptors

2014
The discovery of retinoic acid receptors arose from research into how vitamins are essential for life. Early studies indicated that Vitamin A was metabolized into an active factor, retinoic acid (RA), which regulates RNA and protein expression in cells.
Benbrook, Doris M., Chambon, Pierre, Rochette-Egly, Cécile, Asson-Batres, Mary Ann   +3 more
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Evolution of Retinoic Acid Receptors and Retinoic Acid Signaling

2014
Retinoic acid (RA) is a vitamin A-derived morphogen controlling important developmental processes in vertebrates, and more generally in chordates, including axial patterning and tissue formation and differentiation. In the embryo, endogenous RA levels are controlled by RA synthesizing and degrading enzymes and the RA signal is transduced by two ...
Gutierrez-Mazariegos, Juliana, Schubert, Michael, Laudet, Vincent   +2 more
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Retinoic Acid Receptors in Hematopoiesis

1996
Retinoic acid receptors (RARs) are critical transcriptional regulators that are involved in the development and differentiation of a wide variety of different cells (Evans 1988). Several lines of evidence suggest that RARs may be involved in the regulation of hematopoiesis.
S J, Collins, S, Tsai, I, Bernstein
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