A Novel Tight Junction–Nuclear Receptor Signaling Pathway Regulating Cancer Progression
ABSTRACT Nuclear receptors (NRs) are lipid ligand‐binding transcription factors, with 48 members having been identified in humans to date. They are involved in diverse physiological processes, including development and homeostasis, and are also implicated in the pathogenesis of various diseases, most notably cancer.
Kotaro Sugimoto, Hideki Chiba
wiley +1 more source
The novel E3 ligase of PPAR?? TRIM25 regulates adipocyte differentiation [PDF]
Department of Biological SciencesPeroxisome proliferator-activated receptor ?? (PPAR??) is a ligand-dependent transcription factor which regulates glucose homeostasis and adipocyte differentiation.
Lee, Jae Min
core
ABSTRACT The diversification of Neotropical sigmodontine rodents represents one of the most remarkable evolutionary events among mammals, encompassing numerous endemic, rare, and endangered genera and species. One of the most emblematic examples is Microakodontomys transitorius Hershkovitz 1993, originally described from a single specimen based on ...
Marcelo Weksler+4 more
wiley +1 more source
FOXA1 Reprogramming Dictates Retinoid X Receptor Response in ESR1-Mutant Breast Cancer. [PDF]
Wu Y+12 more
europepmc +1 more source
Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. [PDF]
Rolf Zetterström+4 more
openalex +1 more source
Retinoid X Receptor α Regulates DHA-Dependent Spinogenesis and Functional Synapse Formation In Vivo
Summary: Coordinated intracellular and extracellular signaling is critical to synapse development and functional neural circuit wiring. Here, we report that unesterified docosahexaenoic acid (DHA) regulates functional synapse formation in vivo via ...
Huateng Cao+6 more
doaj
PENGARUH SUPLEMENTASI ISOFLAVON KEDELAI TERHADAP WANITA PENDERITA AKNE VULGARIS : Kajian Jumlah Lesi, Dihydrotestosterone, Toll-Like Receptor-2, dan Interleukin-8 [PDF]
Latar belakang : Akne vulgaris (AV) merupakan penyakit inflamasi kulit yang paling sering dijumpai. Isoflavon kedelai telah terbukti sebagai antiandrogen dan antiinflamasi.
RIYANTO, Puguh
core
ABSTRACT Disease Overview Primary cutaneous lymphomas are a rare and heterogeneous group of extranodal lymphomas that require the integration of clinical and histopathologic data for classification and treatment. Diagnosis Diagnosis and disease classification is based on histopathologic review and immunohistochemical staining of an appropriate skin ...
Alexandra C. Hristov+2 more
wiley +1 more source
Molecular interplay between ecdysone receptor and retinoid X receptor in regulating the molting of the Chinese mitten crab, Eriocheir sinensis. [PDF]
Chen X+5 more
europepmc +1 more source
Endogenous Retinoic Acid Receptor (RAR)-Retinoid X Receptor (RXR) Heterodimers Are the Major Functional Forms Regulating Retinoid-responsive Elements in Adult Human Keratinocytes [PDF]
Jia‐Hao Xiao+3 more
openalex +1 more source