Results 191 to 200 of about 43,565 (303)
Imperatorin Mitigates Rosacea‐Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Xiaoxue Wang, Zexin Zhu
wiley +1 more source
Development of Efficient Supramolecular Photostabilizer for Carotenoids and Retinoids: Analyses and Application Research. [PDF]
Zhao M +12 more
europepmc +1 more source
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Retinoids and Rexinoids in Cancer Prevention: From Laboratory to Clinic [PDF]
Brown, Powel H. +2 more
core +1 more source
Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu +8 more
wiley +1 more source
Rebalancing the Skin: The Microbiome, Acne Pathogenesis, and the Future of Natural and Synthetic Therapies. [PDF]
Oliveira MB +3 more
europepmc +1 more source
Post‐Translational Modifications in Animal Circadian Clocks
Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley +1 more source
Role of transient receptor potential channels on pathogenesis and treatment of psoriasis. [PDF]
da Silva AM +3 more
europepmc +1 more source

