Results 211 to 220 of about 6,615 (304)

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

open access: yesJournal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Recent Advances on Starch-Based Biomaterials: A Review. [PDF]

open access: yesACS Polym Au
Araújo RN   +8 more
europepmc   +1 more source

Feasibility of Comprehensive Genomic Profiling for Biliary Tract Cancer Using Transpapillary Biopsy Samples: A Prospective Study

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Graphical summary of the study design, intervention, and outcomes. ABSTRACT Background Patients with biliary tract cancer (BTC) often have actionable mutations, and comprehensive genomic profiling (CGP) plays an important role. However, the feasibility of CGP using transpapillary biopsy (TPB) samples remains unclear.
Kazuya Miyamoto   +9 more
wiley   +1 more source

Clinical Evaluation of the Effectiveness of Digital Peroral Cholangioscopy‐Guided Lithotripsy for Difficult Bile Duct Stones

open access: yesJournal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Background and Aims Peroral cholangioscopy‐guided lithotripsy (POCS‐L) has emerged as a treatment option for difficult bile duct stones (DBDSs), but detailed evidence remains limited. This study evaluated its effectiveness, safety, and risk factors for adverse events (AEs).
Hirohito Minami   +9 more
wiley   +1 more source

Tracking Summer Greenland Blocking: The Upstream Pathway Shapes Historical Extremes and Future Change

open access: yesInternational Journal of Climatology, EarlyView.
This study investigates summer Greenland atmospheric blocking using the Lagrangian tracking Python package blocktrack applied to ERA5 reanalysis and CMIP6 models. Two types of blocks—upstream (Northern Canada origin) and retrograding (Northern Atlantic origin)—are distinguished, with upstream blocks driving recent observed frequency increasing trends ...
Michele Filippucci   +2 more
wiley   +1 more source

Updated ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease 2025

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi   +35 more
wiley   +1 more source

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