Results 1 to 10 of about 70 (67)
Retrograde signals galore [PDF]
Frontiers in Plant Science, 2013 The term “retrograde signaling” refers to the concept that signals originating from chloroplasts or mitochondria can modulate nuclear gene expression (NGE). The evolutionary establishment of the complex mechanisms underlying retrograde signaling is likely to have required a long time period (reviewed in: Tanaka and Hanaoka, 2012).
Kleine, Tatjana, Leister, Dario
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On Trk for Retrograde Signaling [PDF]
Neuron, 2001 Target-derived neurotrophins like nerve growth factor (NGF) mediate biological effects by binding to and activating Trk neurotrophin receptors at nerve terminals. The activated Trk receptors then stimulate local effects at nerve terminals, and retrograde effects at neuronal cell bodies that often reside at considerable distances from the terminals ...
Miller, Freda D, Kaplan, David R
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Retrograde Signaling Causes Excitement [PDF]
Neuron, 2014 Retrograde signaling is a powerful tool to shape synaptic transmission, typically inducing inhibition of transmitter release. A new study published in this issue of Neuron by Carta et al. (2014) now provides strong support for arachidonic acid as a potentiating retrograde messenger.
Schmitz, Dietmar +2 more
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Retrograde signaling at central synapses [PDF]
Proceedings of the National Academy of Sciences, 2001 Transcellular retrograde signaling from the postsynaptic target cell to the presynaptic neuron plays critical roles in the formation, maturation, and plasticity of synaptic connections. We here review recent progress in our understanding of the retrograde signaling at developing central synapses.
H W, Tao, M, Poo
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Mitochondrial retrograde signalling in neurological disease [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2020 Neuronal mitochondrial dysfunction causes primary mitochondrial diseases and likely contributes to neurodegenerative diseases including Parkinson's and Alzheimer's disease. Mitochondrial dysfunction has also been documented in neurodevelopmental disorders such as tuberous sclerosis complex and autism spectrum disorder. Only symptomatic treatments exist
Lucy Granat +2 more
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Oxylipins in plastidial retrograde signaling
Redox Biology, 2020 Oxylipins (compounds derived from the oxidation of polyunsaturated fatty acids) are essential in retrograde signaling emanating from plastids to the nucleus during plant developmental and stress responses. In this graphical review, we provide an overview of the chemical structure, biosynthesis and role of oxylipins, as both redox and hormonal signals ...
Paula Muñoz, Sergi Munné-Bosch
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AEXpulsing a Retrograde Signal [PDF]
Neuron, 2002 A variety of secreted components have been identified as retrograde signals mediating diverse aspects of synaptic development, maintenance, and plasticity; however, little is known about the mechanisms mediating the release of secreted retrograde signals.
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From retrograde signaling to flowering time [PDF]
Plant Signaling & Behavior, 2015 Plant's transition from vegetative to reproductive phase is balanced by intricate cascade of genes regulated by both endogenous and environmental inputs. Stress causes suppression of vegetative growth and acceleration of flowering as an emergency response for preservation of the species. Recently, we determined that expression levels of a transcription
Changquan Wang, Katayoon Dehesh
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Mitochondrial retrograde signaling in the nervous system [PDF]
FEBS Letters, 2017 Mitochondria generate the majority of cellular ATP and are essential for neuronal function. Loss of mitochondrial activity leads to primary mitochondrial diseases and may contribute to neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Mitochondria communicate with the cell through mitochondrial retrograde signaling pathways. These
Rachel J. Hunt, Joseph M. Bateman
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A new alternative in plant retrograde signaling [PDF]
Genome Biology, 2014 AbstractThe reduced or oxidized state of plastoquinone in chloroplasts regulates splicing in the nucleus to control nuclear gene expression in response to changing environmental conditions.
Jung, Hou-Sung, Mockler, Todd C
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