Results 21 to 30 of about 995,941 (287)

Retrograde signals galore [PDF]

Frontiers in Plant Science, 2013
The term “retrograde signaling” refers to the concept that signals originating from chloroplasts or mitochondria can modulate nuclear gene expression (NGE). The evolutionary establishment of the complex mechanisms underlying retrograde signaling is likely to have required a long time period (reviewed in: Tanaka and Hanaoka, 2012).
Kleine, Tatjana, Leister, Dario
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On Trk for Retrograde Signaling [PDF]

Neuron, 2001
Target-derived neurotrophins like nerve growth factor (NGF) mediate biological effects by binding to and activating Trk neurotrophin receptors at nerve terminals. The activated Trk receptors then stimulate local effects at nerve terminals, and retrograde effects at neuronal cell bodies that often reside at considerable distances from the terminals ...
Miller, Freda D, Kaplan, David R
openaire   +2 more sources

Retrograde signaling from autophagy modulates stress responses [PDF]

, 2017
Macroautophagy is a process in which cytoplasmic components, including whole organelles, are degraded within lysosomes. Basally, this process is essential for homeostasis and is constitutively functional in most cells, but it can also be implemented as ...
Simon, Hans-Uwe, Friis, Robert, Hans-Uwe Simon, Stephen W. G. Tait, Ryan, Kevin M., Robert Friis, Tait, Stephen W.G., Kevin M. Ryan, Ryan, Kevin M, Tait, Stephen W G, Tait SW, Simon HU, Friis R, Ryan KM   +13 more
core   +3 more sources

Nuclear-Mitochondrial Interactions

Biomolecules, 2022
Mitochondria, the cell’s major energy producers, also act as signaling hubs, interacting with other organelles both directly and indirectly. Despite having its own circular genome, the majority of mitochondrial proteins are encoded by nuclear DNA.
Brittni R. Walker, Carlos T. Moraes
doaj   +1 more source

The transcription factor ANAC017 links mitochondrial retrograde signaling with the ubiquitin-proteasome system to control mitochondrial function in Arabidopsis. [PDF]

Plant Commun
The transcription factor ANAC017 links mitochondrial retrograde signaling with the ubiquitin–proteasome system to control mitochondrial function in ...
Zhao Y, Ogden M, Pan R, Hu J, Persson S, Murcha MW, Shou H, Wang Y, Khan GA, Whelan J.   +9 more
europepmc   +2 more sources

Retrograde signaling at central synapses [PDF]

Proceedings of the National Academy of Sciences, 2001
Transcellular retrograde signaling from the postsynaptic target cell to the presynaptic neuron plays critical roles in the formation, maturation, and plasticity of synaptic connections. We here review recent progress in our understanding of the retrograde signaling at developing central synapses.
H W, Tao, M, Poo
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Plastid retrograde signaling: A developmental perspective. [PDF]

Plant Cell
Abstract Chloroplast activities influence nuclear gene expression, a phenomenon referred to as retrograde signaling. Biogenic retrograde signals have been revealed by changes in nuclear gene expression when chloroplast development is disrupted.
Loudya N, Barkan A, López-Juez E.
europepmc   +3 more sources

Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2017
In Saccharomyces cerevisiae mitochondrial dysfunction induces retrograde signaling, a pathway of communication from mitochondria to the nucleus that promotes a metabolic remodeling to ensure sufficient biosynthetic precursors for replication.
Rafaela Maria Rios-Anjos, Vittoria de Lima Camandona, Lucas Bleicher, Jose Ribamar Ferreira-Junior   +3 more
doaj   +1 more source

AEXpulsing a Retrograde Signal [PDF]

Neuron, 2002
A variety of secreted components have been identified as retrograde signals mediating diverse aspects of synaptic development, maintenance, and plasticity; however, little is known about the mechanisms mediating the release of secreted retrograde signals.
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Mitochondrial retrograde signalling in neurological disease [PDF]

Philosophical Transactions of the Royal Society B: Biological Sciences, 2020
Neuronal mitochondrial dysfunction causes primary mitochondrial diseases and likely contributes to neurodegenerative diseases including Parkinson's and Alzheimer's disease. Mitochondrial dysfunction has also been documented in neurodevelopmental disorders such as tuberous sclerosis complex and autism spectrum disorder. Only symptomatic treatments exist
Lucy Granat, Rachel J. Hunt, Joseph M. Bateman   +2 more
openaire   +2 more sources