Results 11 to 20 of about 49,871 (252)
Retrograde signals galore [PDF]
Frontiers in Plant Science, 2013 The term “retrograde signaling” refers to the concept that signals originating from chloroplasts or mitochondria can modulate nuclear gene expression (NGE). The evolutionary establishment of the complex mechanisms underlying retrograde signaling is likely to have required a long time period (reviewed in: Tanaka and Hanaoka, 2012).
Kleine, Tatjana, Leister, Dario
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Ras-ERK-ETS inhibition alleviates neuronal mitochondrial dysfunction by reprogramming mitochondrial retrograde signaling. [PDF]
PLoS Genetics, 2018 Mitochondrial dysfunction activates the mitochondrial retrograde signaling pathway, resulting in large scale changes in gene expression. Mitochondrial retrograde signaling in neurons is poorly understood and whether retrograde signaling contributes to ...
Olivia F Duncan +8 more
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On Trk for Retrograde Signaling [PDF]
Neuron, 2001 Target-derived neurotrophins like nerve growth factor (NGF) mediate biological effects by binding to and activating Trk neurotrophin receptors at nerve terminals. The activated Trk receptors then stimulate local effects at nerve terminals, and retrograde effects at neuronal cell bodies that often reside at considerable distances from the terminals ...
Miller, Freda D, Kaplan, David R
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The Role of Tetrapyrrole- and GUN1-Dependent Signaling on Chloroplast Biogenesis
Plants, 2021 Chloroplast biogenesis requires the coordinated expression of the chloroplast and nuclear genomes, which is achieved by communication between the developing chloroplasts and the nucleus.
Takayuki Shimizu, Tatsuru Masuda
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Kinesin Khc-73/KIF13B modulates retrograde BMP signaling by influencing endosomal dynamics at the Drosophila neuromuscular junction. [PDF]
PLoS Genetics, 2018 Retrograde signaling is essential for neuronal growth, function and survival; however, we know little about how signaling endosomes might be directed from synaptic terminals onto retrograde axonal pathways.
Edward H Liao +9 more
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Nuclear-Mitochondrial Interactions
Biomolecules, 2022 Mitochondria, the cell’s major energy producers, also act as signaling hubs, interacting with other organelles both directly and indirectly. Despite having its own circular genome, the majority of mitochondrial proteins are encoded by nuclear DNA.
Brittni R. Walker, Carlos T. Moraes
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Retrograde signaling at central synapses [PDF]
Proceedings of the National Academy of Sciences, 2001 Transcellular retrograde signaling from the postsynaptic target cell to the presynaptic neuron plays critical roles in the formation, maturation, and plasticity of synaptic connections. We here review recent progress in our understanding of the retrograde signaling at developing central synapses.
H W, Tao, M, Poo
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Retrograde Signaling Causes Excitement [PDF]
Neuron, 2014 Retrograde signaling is a powerful tool to shape synaptic transmission, typically inducing inhibition of transmitter release. A new study published in this issue of Neuron by Carta et al. (2014) now provides strong support for arachidonic acid as a potentiating retrograde messenger.
Schmitz, Dietmar +2 more
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Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2017 In Saccharomyces cerevisiae mitochondrial dysfunction induces retrograde signaling, a pathway of communication from mitochondria to the nucleus that promotes a metabolic remodeling to ensure sufficient biosynthetic precursors for replication.
Rafaela Maria Rios-Anjos +3 more
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Frontiers in Plant Science, 2023 Retrograde signals sent by chloroplasts control transcription in the nucleus. These signals antagonistically converge with light signals to coordinate the expression of genes involved in chloroplast functioning and seedling development.
Guiomar Martín
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