Results 101 to 110 of about 888 (124)

Histone and non-histone (de)acetylation impact on the blood-brain barrier. [PDF]

Fluids Barriers CNS
Melo M, Fortuna A, Laranjinha J, Bicker J.   +3 more
europepmc   +1 more source

Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus. [PDF]

Nat Commun
Franz H, Rathod M, Zimmermann A, Stüdle C, Beyersdorfer V, Leal-Fischer K, Hanns P, Cunha T, Didona D, Hertl M, Scheibe M, Butter F, Schmidt E, Spindler V.   +13 more
europepmc   +1 more source

GNAS knockout potentiates HDAC3 inhibition through viral mimicry-related interferon responses in lymphoma. [PDF]

Leukemia
He MY, Tong KI, Liu T, Whittaker Hawkins R, Shelton V, Zeng Y, Bakhtiari M, Xiao Y, Zheng G, Sakhdari A, Yang L, Xu W, Brooks DG, Laister RC, He HH, Kridel R.   +15 more
europepmc   +1 more source

Epigenetic Therapies for Inflammatory and Immune-Mediated Skin Diseases. [PDF]

Biomedicines
Makridou A, Elemes DI, Liakou ME, Theotokis P, Gargani S, Vakirlis E, Meditskou S, Onoufriadis A, Manthou ME, Dermitzakis I.   +9 more
europepmc   +1 more source

Role of HDAC3 in the epithelial-mesenchymal transition of retinal pigment epithelium cells: Implications for proliferative vitreoretinopathy. [PDF]

Heliyon
Zou W, Huang C, Chen Y, Tang J, Li Q, Fang Q, Ma Y, Wu W, Feng S.   +8 more
europepmc   +1 more source

The role of HDAC3 in inflammation: mechanisms and therapeutic implications. [PDF]

Front Immunol
Watson N, Kuppuswamy S, Ledford WL, Sukumari-Ramesh S.   +3 more
europepmc   +1 more source

LincRNA-p21: A Double-Edged Sword in Ethanol-Induced Liver Damage and Its Nanoparticle Solution. [PDF]

Int J Nanomedicine
Wang S, Nie ZC, Liu Y, Zhang ZY, Feng YM, Wang C, Jiang J.   +6 more
europepmc   +1 more source

Macrophagic HDAC3 inhibition ameliorates Dextran Sulfate Sodium induced inflammatory bowel disease through GBP5-NLRP3 pathway. [PDF]

Int J Med Sci
Che N, Zhang Y, Zhang S, Kong X, Zhang Y, Wang S, Yuan Z, Liao Y.   +7 more
europepmc   +1 more source

Correction to: Expanded CAG/CTG repeats resist gene silencing mediated by targeted epigenome editing. [PDF]

Hum Mol Genet
europepmc   +1 more source

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RGFP966 is protective against lipopolysaccharide-induced depressive-like behaviors in mice by inhibiting neuroinflammation and microglial activation

International Immunopharmacology, 2021
Depression is a prevalent mental disorder. However, its pathophysiological mechanism has still remained elusive, and a limited number of effective treatments have been presented. Recent studies have shown that neuroinflammation and microglial activation are involved in the pathogenesis of depression. Histone deacetylase 3 (HDAC3) has neurotoxic effects
Gao-Hua Wang, Ling Xiao, Hui-Ling Wang   +2 more
exaly   +3 more sources