Results 81 to 90 of about 63,147 (208)
RhoA and Rac1 in Liver Cancer Cells: Induction of Overexpression Using Mechanical Stimulation
, 2020 Liver cancer, especially hepatocellular carcinoma (HCC), is an aggressive disease with an extremely high mortality rate. Unfortunately, no promising markers are currently available for the early diagnosis of this disease.
Nguyen, NT +5 more
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, 2012 Secretion of proinflammatory cytokines by LPS activated endothelial cells contributes substantially to the pathogenesis of sepsis. However, the mechanism involved in this process is not well understood. In the present study, we determined the roles of GEF-
Derek Van Lonkhuyzen +13 more
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A RhoA-FRET Biosensor Mouse for Intravital Imaging in Normal Tissue Homeostasis and Disease Contexts
Cell Reports, 2017 The small GTPase RhoA is involved in a variety of fundamental processes in normal tissue. Spatiotemporal control of RhoA is thought to govern mechanosensing, growth, and motility of cells, while its deregulation is associated with disease development ...
Max Nobis +42 more
doaj +1 more source
Mapping of the RhoA cleavage site.
, 2016 A) Coomassie brilliant blue-stained SDS-Page gel of FL-RhoA and RhoA-NTF showing the bands excised (boxes) for tandem mass spectrometry. B) Alignment of the peptides obtained by mass spectrometry of RhoA-NTF following trypsin (red) or chymotrypsin (blue)
Madeline Pool (3592508) +4 more
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RhoA/ROCK pathway in cardiovascular system.
, 2023 Contractile agonist (Gq/11) produces 1P3 which binds to its receptor and releases calcium. Calcium/calmodulin complex activates MLCK that phosphorylate MLC and performs calcium dependent contraction.
Iqra Ali (15372725) +5 more
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, 2012 (a) PTP knockdowns are rescued by active or dominant negative RhoA. Embryos were micro-injected at the one cell stage using morpholinos (high concentration) targeting the indicated genes together with no RNA, RNA encoding constitutively active RhoA (3 pg/
Vincent Runtuwene (170350) +3 more
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Report: RHOA and RCA Task Force, May 1984
, 2006 Report: photocopy, 11" x 8.5" (29.7cm x 21.6cm), pages include handwritten notes, questions, underlines and drawingsFinal Report of the Reston Homeowners Association (RHOA) and Reston Community Association (RCA) Land Use Committee, submitted to the RCA ...
RHOA and RCA Task Force
core
Compression induced RhoA activation and phosphorylation.
, 2015 (A) Detection of active RhoA under compressive loading. Active RhoA (RhoA-GTP) was precipitated with Rhotekin-RBD beads. Total RhoA was used as a loading control. (B) Western blotting for phosphorylated RhoA after compressing cells.
Hisashi Haga (443431) +4 more
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, 2016 Surface topography broadly influences cellular responses. Adherent cell activities are regulated, in part, by RhoA, a member of the Rho-family of GTPases.
Mendonça, Daniela B.S. +6 more
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CellsRhoA is a major regulator of the actin cytoskeleton. Its function in the nucleus, however, is unclear. Fusing wildtype, fast cycling, constitutively active, and dominant negative forms of RhoA with tags promoting nuclear or cytoplasmic location and ...
Lap P. Nguyen +4 more
doaj +1 more source