DNA repair systems and the pathogenesis of Mycobacterium tuberculosis: varying activities at different stages of infection [PDF]
Mycobacteria, including most of all MTB (Mycobacterium tuberculosis), cause pathogenic infections in humans and, during the infectious process, are exposed to a range of environmental insults, including the host's immune response.
Adams +117 more
core +1 more source
Hidradenitis suppurativa (HS) is often diagnosed late, complicating management. In this nationwide Danish study including 10,196 patients with dermatologist‐verified HS, we examined treatment patterns before and after referral to specialised hospital care.
Nana A. L. Rosenø +8 more
wiley +1 more source
Rifampicin-Loaded Mesoporous Silica Nanoparticles for the Treatment of Intracellular Infections
Infectious diseases remain a major burden in today’s world, causing high mortality rates and significant economic losses, with >9 million deaths per year predicted by 2030.
S. Subramaniam +5 more
semanticscholar +1 more source
Multi-Fluorescence Real-Time PCR Assay for Detection of RIF & INH Resistance of M. tuberculosis
Background: Failure to early detect multidrug-resistant tuberculosis (MDR-TB) results in treatment failure and poor clinical outcomes, and highlights the need to rapidly detect resistance to rifampicin (RIF) and isoniazid (INH)Methods: In Multi ...
Jingfu ePeng +11 more
doaj +1 more source
Antituberculosis Activity of Brotowali (Tinospora Crispa) Extract and Fractions Against Mycobacterium Tuberculosis Using Microplate Alamar Blue Assay Method [PDF]
Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases.
Irianti, T. (Tatang) +5 more
core
The study reveals the inhibitory potential of encapsulated nanoparticles functionalized with moxifloxacin hydrochloride. ABSTRACT Bacterial resistance represents a significant global health threat associated with the development of microbial resistance genes.
Amanda S. Abreu +6 more
wiley +1 more source
Safety and efficacy of colistin versus meropenem in the empirical treatment of ventilator-associated pneumonia as part of a macro-project funded by the Seventh Framework Program of the European Commission studying off-patent antibiotics. study protocol for a randomized controlled trial [PDF]
Background: Ventilator-associated pneumonia (VAP) is one of the most common and severe hospital-adquired infections, and multidrugresistant gram-negative bacilli (MDR-GNB) constitute the main etiology in many countries.
Clara Rosso, Fernández +6 more
core +1 more source
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Impact of COVID-19 pandemic on tuberculosis [PDF]
Background: Tuberculosis (TB) is a disease of the respiratory system that spreads when a patient coughs, sneezes, or spits. COVID-19, another respiratory disease, created havoc in 2020 and 2021.
Sae Pol +5 more
doaj
Impact of Human Immunodeficiency Virus Infection on the Outcome of Treatment and Survival of Tuberculosis Patients in Mwanza, Tanzania. [PDF]
Little is known about the outcome of tuberculosis (TB) treatment and subsequent survival of human immunodeficiency virus (HIV) infected patients treated under routine programme conditions in a developing country.
Lefi, M +5 more
core

