Results 131 to 140 of about 156,396 (269)

Engineering of 10‐Deacetylbaccatin III‐10‐β‐O‐Acetyltransferase From Taxus Species for Efficient Acetylating Non‐Natural Substrates Into Taxol in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT 7‐β‐xylosyl‐10‐deacetyltaxol (XDT) is much more abundant than the anticancer drug Taxol in Taxus species and is usually regarded as the by‐product of Taxol. It could be enzymatically transformed into 10‐deacetyltaxol (DT), and the latter could be further converted into Taxol.
Tian‐Jiao Chen, Jing‐Jing Chen, Xiao‐Yan Sun, Ting Gong, Jin‐Ling Yang, Ping Zhu   +5 more
wiley   +1 more source

Penetration of rifampicin into the brain tissue and cerebral extracellular space of rats [PDF]

, 2017
Rifampicin is used to treat neurosurgical shunt infections because of its excellent in-vitro activity against staphylococci and its adequate penetration into the CSF. However, nothing is known about rifampicin concentrations in the cerebral extracellular
Gratzl, Otmar, Landolt, Hans, Mindermann, Thomas, Rajacic, Zarko, Zimmerli, Werner   +4 more
core  

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao, Hui‐Xin Meng, Xue‐Jiao Xu, Zeng‐Lin Zhang, Jian‐Feng Zhang, Yong‐Feng Guo, Inhwan Hwang, Shi‐Jian Song   +7 more
wiley   +1 more source

Poplar miR1447 Is a Negative Regulator of Disease Resistance Through the SA‐Dependent Pathway

Plant Biotechnology Journal, EarlyView.
ABSTRACT Although microRNA1447 (miR1447) regulates poplar responses to abiotic stress and pest infestation, how miR1447 regulates poplar immunity against pathogens and its underlying molecular mechanisms remain to be elucidated. Here, we revealed that miR1447 functioned as a negative regulator of poplar disease resistance against fungal and bacterial ...
Dandan Xiao, Kaijing Rong, Tiantian Fu, Yicheng Li, Chun Wang, Ke Zhou, Ruen Yu, Xiaoqian Yang, Yuzhang Yang, Yuanyuan Wang, Yanwei Wang, Yonglin Wang   +11 more
wiley   +1 more source

Host‐Induced Silencing of Rhizoctonia Solani 5‐Enolpyruvylshikimate‐3‐Phosphate Synthase Impairs Its Virulence in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar, Apoorva Prasad, Akshita Goel, Vijay Kumar Sharma, Jagjeet Singh Lore, Arun Kumar   +5 more
wiley   +1 more source

A case of treatment for pulmonary infection caused by multidrug‐resistant Acinetobacter baumannii

Respirology Case Reports
Acinetobacter baumannii is a major pathogen in hospital‐acquired infections notorious for its strong acquired resistance and complex drug resistance mechanisms.
Chenxia Guo, Shaohua Xu, Wei Yan
doaj   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, EarlyView.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

The Advantaged Salt Inducible Suaeda salsa SsNRT2.5 and Its Promoter Significantly Enhance Nitrate Transport Efficiency and Salt Tolerance in Transgenic Arabidopsis and Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient nitrogen (N) uptake is critical for crop yield, but soil salinization inhibits plant nitrogen acquisition. In this study, the nitrate (NO3−) transporter gene SsNRT2.5 and its promoter from the halophyte Suaeda salsa was investigated to elucidate the functional role in NO3− transport under salinity and low NO3−–N conditions.
Ranran Liu, Chenyang Li, Runtai Zhao, Congcong Song, Yan Zhou, Ruxin Zhao, Na Sui, Lei Wang, Jie Song   +8 more
wiley   +1 more source

Systemic Delivery of Functional Proteins Into Plants Using an Engineered Membrane Translocation Domain

Plant Biotechnology Journal, EarlyView.
ABSTRACT Protein‐based biopesticides and biostimulants are critical for the future of sustainable agriculture, yet their utility is severely limited by inefficient delivery into plant cells. Traditional cell‐penetrating peptides enable protein uptake but lack the efficiency, systemic activity and scalability required for crop production.
Jiyang Wang, Preeti Patel, Prabhat Bhat, Cailin Hu, Cameron Storch, Brendan Harty, Maria Bellizzi, Colton Jordan, Devin Good, Venkat Gopalan, Jonathan Michael Jacobs, Dehua Pei, Guo‐Liang Wang   +12 more
wiley   +1 more source

Dual‐vector transmission of a pepper polerovirus: a plant virus is transmitted by both aphids and the supervector whitefly Bemisia tabaci

New Phytologist, EarlyView.
José Natividad Jaén‐Sanjur, Ana Cristina García‐Merenciano, Jesús Navas‐Castillo, Elvira Fiallo‐Olivé   +3 more
wiley   +1 more source