Results 131 to 140 of about 191,709 (318)

Inconsistent standard of care for tuberculosis screening and preventive therapy before initiating systemic psoriasis treatment

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Preventive tuberculosis (TB) therapy before initiating MTX or IL‐17/IL‐23/IL‐12/23p40 inhibitors for latent tuberculosis infection (LTBI) is supported by indirect evidence of TB reactivations with TNF inhibitors. However, direct evidence for MTX or IL‐17/IL‐23/IL‐12/23p40 inhibitors is limited.
Christoph Zeyen, Ruben Heuer, Brit Haecker, Tom Schaberg, Alexander Nast   +4 more
wiley   +1 more source

Roles of transcription factors, RBPA and SIGF, in the mycobacterium tuberculosis [PDF]

, 2016
The mechanism of prokaryotic transcription has been characterized primarily in the classic system, Escherichia coli, and cannot be confidently extended to include other prokaryotic species, such as those of the Actinobacteria phylum.
Pope, Steven Scott
core   +1 more source

Investigations on biological activity of Vetiveria zizanioides L. Nash, a palingenesis of some important findings in miracle grass [PDF]

, 2012
Vetiveria zizanioides L. Nash synonymously known as Chrysopogon zizanioides L. Roberty (Family: Poaceae/Graminae), widely cultivated in the tropical regions of the world, is a miraculous grass native to India first developed for soil and water ...
Suaib Luqman
core   +2 more sources

Persistent Facial Nodules in an Elderly Patient

JEADV Clinical Practice, EarlyView.
Qian Ding, Qin‐Si Liu, Heng‐Guang Zhao   +2 more
wiley   +1 more source

The Potential for Treatment Shortening With Higher Rifampicin Doses: Relating Drug Exposure to Treatment Response in Patients With Pulmonary Tuberculosis

Clinical Infectious Diseases, 2018
We used advanced model-based methods to characterize the relationship between individual rifampicin exposure and antituberculosis treatment response. With data from a trial investigating high-dose rifampicin, a significant relation could be derived, and ...
E. Svensson, Robin J. Svensson, L. T. Te Brake, M. Boeree, N. Heinrich, Sarah Konsten, G. Churchyard, R. Dawson, A. Diacon, G. Kibiki, L. Minja, N. E. Ntingiya, I. Sanne, S. Gillespie, M. Hoelscher, P. Phillips, U. Simonsson, R. Aarnoutse   +17 more
semanticscholar   +1 more source

Widespread Skin Lesions in an Italian Man

JEADV Clinical Practice, EarlyView.
Rebecca Donadoni, Giulia Merlo, Gabriele Zanardi, Antonio Guadagno, Corrado Cabona, Stefania Artioli, Claudia Micalizzi, Emanuele Cozzani   +7 more
wiley   +1 more source

Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis

Journal of Antimicrobial Chemotherapy, 2018
Objectives The objectives of this study were to explore inter-study heterogeneity in the pharmacokinetics (PK) of orally administered rifampicin, to derive summary estimates of rifampicin PK parameters at standard dosages and to compare these with ...
Katharine E. Stott, Henry E Pertinez, M. Sturkenboom, M. Boeree, R. Aarnoutse, G. Ramachandran, Ana Requena-Méndez, C. Peloquin, C. Koegelenberg, J. Alffenaar, R. Ruslami, Alma Tostmann, Soumya Swaminathan, H. McIlleron, Geraint Davies   +14 more
semanticscholar   +1 more source

A Population Pharmacokinetic Model Incorporating Saturable Pharmacokinetics and Autoinduction for High Rifampicin Doses

Clinical pharmacology and therapy, 2017
Accumulating evidence suggests that increasing doses of rifampicin may shorten tuberculosis treatment. The PanACEA HIGHRIF1 trial assessed safety, pharmacokinetics, and antimycobacterial activity of rifampicin at doses up to 40 mg/kg.
Robin J. Svensson, R. Aarnoutse, A. Diacon, R. Dawson, S. Gillespie, M. Boeree, U. Simonsson   +6 more
semanticscholar   +1 more source

Reduced fecundity associated with Wolbachia infection in a Neotropical drosophilid Redução da fecundidade associada à infecção por Wolbachia em um drosofilídeo Neotropical

Ecological Entomology, EarlyView.
Using multiple infected and uninfected Drosophila sturtevanti lines, we investigated (i) the impact of Wolbachia on fecundity and (ii) its effects relative to antibiotic treatment. Based on over 1680 dissected ovaries, fecundity was similar between infected and uninfected flies.
Letícia Carlesso de Paula Sena, Marina Magalhães Moreira, Luísa de Paula Bouzada Dias, Jhonny José Magalhães Guedes, Karla Suemy Clemente Yotoko   +4 more
wiley   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source