Pharmacokinetic interactions between rifampicin and efavirenz in HIV-TB coinfections [PDF]
The increased percentage of patients with HIV-TB coinfection leads to inevitable interactions between rifampicin and efavirenz. Efavirenz is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV infection.
Yenny
doaj
Abstract Introduction People with tuberculosis‐HIV coinfection face multiple barriers to effective treatment, including social vulnerability, stigma and limited access to healthcare. This study examined factors associated with loss to follow‐up and death among individuals with tuberculosis‐HIV in Brazil.
Lucas Vinícius de Lima +9 more
wiley +1 more source
Effect of bacterial inoculation, plant genotype and developmental stage on root-associated and endophytic bacterial communities in potato (Solanum tuberosum) [PDF]
Beneficial bacteria interact with plants by colonizing the rhizosphere and roots followed by further spread through the inner tissues, resulting in endophytic colonization.
Andreote, F.D. +4 more
core +2 more sources
Forty‐three HS specialists from 22 European countries reported adherence to HS guidelines and use of antibiotics before biologics despite limited efficacy and rapid relapse (49% within 1–3 months). Seventy‐nine per cent supported short‐term biologics for severe Hurley I disease.
Georgios Nikolakis +41 more
wiley +1 more source
Hair follicle stem cell fate supports distinct clinical endotypes in hidradenitis suppurativa
Hair follicles (HFs) were extracted from skin biopsies. From these, original sequencing data were obtained and integrated with two independent studies to build a HF single‐cell transcriptomic atlas. It enabled delineating the fate of HF stem cells.
Audrey Onfroy +17 more
wiley +1 more source
Thymine starvation causes abortive initiation of chromosome replication critical for cell death in Escherichia coli [PDF]
Presentado en: XXXVI Congreso SEBBM (Sociedad Española de Bioquímica y Biología Molecular), Madrid, 4-6 septiembre, 2013Thymineless death (TLD), a phenomenon in which thymine auxotrophy becomes lethal when cells are starved for thymine, can be prevented
Guzmán Cabañas, Elena +2 more
core
Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis +54 more
wiley +1 more source
In vitro activity of rifampicin, rifapentine and rifabutin against South Indian isolates of M. tuberculosis [PDF]
M. tuberculosis isolates from 51 resistant and 52 susceptible to Rifampicin patients were concurrently tested for in vitro susceptibility to Rifampicin, Rifapentine and Rifabutin. All the 52 Rifampicin susceptible strains were susceptible to Rifapentine,
Paramasivan, C N +2 more
core
Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac +15 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Neda Cramer +3 more
wiley +1 more source

