Results 161 to 170 of about 191,709 (318)

Development of Modular Geminivirus‐Based Vectors for High Cargo Expression and Gene Targeting in Plants

Plant Biotechnology Journal, EarlyView.
ABSTRACT Viral vectors can be useful tools for expressing recombinant proteins as well as delivering gene‐editing machinery. Despite their utility, the development and subsequent optimisation of these tools is often a difficult and tedious process.
Matthew Neubauer, Katie Vollen, Chengsong Zhao, José T. Ascencio‐Ibáñez, Linda Hanley‐Bowdoin, Anna N. Stepanova, Jose M. Alonso   +6 more
wiley   +1 more source

Corynebacterium striatum‐Associated Pyogenic Osteomyelitis With Direct Extension From Postoperative Empyema

Respirology Case Reports
Corynebacterium striatum can cause postoperative empyema. C. striatum‐associated empyema may be associated with osteomyelitis. Rifampicin is a viable therapeutic option for C. striatum infection.
Shinnosuke Fukushima, Kazuhiro Noma, Hideharu Hagiya   +2 more
doaj   +1 more source

Development and Validation of a UPLC-MS/MS Method for Therapeutic Drug Monitoring, Pharmacokinetic and Stability Studies of First-Line Antituberculosis Drugs in Urine

Molecules
Tuberculosis (TB) remains one of the leading global causes of mortality. Several methods have been established to detect anti-TB agents in human plasma and serum. However, there is a notable absence of studies analyzing TB drugs in urine.
Mohamed Abouzid, Katarzyna Kosicka-Noworzyń, Marta Karaźniewicz-Łada, Prakruti Rao, Nisha Modi, Yingda L. Xie, Scott K. Heysell, Anna Główka, Leonid Kagan   +8 more
doaj   +1 more source

A Fungal Cysteine‐Rich Protein SsSCP Activates Immune Responses and Confers Broad‐Spectrum Disease Resistance in Tomato

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant immune systems recognise pathogen‐derived molecular patterns to activate defence responses, yet the mechanisms underlying fungal pattern recognition in crops remain largely unclear. Here, we characterise the cysteine‐rich secretory protein SsSCP from the broad‐host‐range fungal pathogen Sclerotinia sclerotiorum as a potent elicitor of ...
Liyuan Zhang, Yuan Wang, Yuhang Liu, Jinwen Yang, Kaihao Zhang, Chengzhang Du, Jiajing Xiao, Ling Qing, Xinhua Sun   +8 more
wiley   +1 more source

Overexpression of a Tonoplast Malate Transporter Gene Leads to Enhanced Anthocyanin Biosynthesis in Apple

Plant Biotechnology Journal, EarlyView.
ABSTRACT Anthocyanins, a group of secondary metabolites synthesised in the phenylpropanoid pathway, largely determine the peel colour of fleshy fruits, but it is not known if their synthesis is linked to vacuolar malate accumulation that underlies fruit acidity.
Mengxia Zhang, Jiahao Zhao, Nan Wang, Da‐Gang Hu, Ewa Borejsza‐Wysocka, Lailiang Cheng   +5 more
wiley   +1 more source

Cutaneous tuberculosis (scrofuloderma) in a five year-old boy: Case report [PDF]

, 2009
Cutaneous tuberculosis (CTB) is a rare form of extrapulmonary TB in our region. The incidence of CTB seems to be increasing in some countries. CTB continues to be one of the most elusive and difficult diagnoses to make for dermatologists practicing in ...
Dehghan, M., Kazeminezhad, V., Najafi, L.   +2 more
core  

Heterologous Production of Forskolin in Tobacco (Nicotiana tabacum) via Glandular Trichome Specific Engineering and Metabolic Flux Redirection

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plants are promising bioreactor for the sustainable and scalable production of high‐value natural bioactive compounds, because they can synthesise phytochemicals from CO2, light, water and minerals through their innate photosynthetic carbon assimilation machinery.
Xuan Sun, Xiuming Wu, Xun Jiang, Hongmei Huang, Aiguo Yang, Yiting Li, Zhenjun Fan, Aixia Chang, Changqing Yang   +8 more
wiley   +1 more source

Penetration of rifampicin into the brain tissue and cerebral extracellular space of rats [PDF]

, 2017
Rifampicin is used to treat neurosurgical shunt infections because of its excellent in-vitro activity against staphylococci and its adequate penetration into the CSF. However, nothing is known about rifampicin concentrations in the cerebral extracellular
Gratzl, Otmar, Landolt, Hans, Mindermann, Thomas, Rajacic, Zarko, Zimmerli, Werner   +4 more
core  

OrchidMD: An Integrated and User‐Interactive Orchid Multi‐Omics Database for Mining Genes and Biological Research

Plant Biotechnology Journal, EarlyView.
ABSTRACT The Orchidaceae family, with its unparalleled species diversity among angiosperms, is integral to ornamental, medicinal, cultural, and ecological value. Multi‐omics techniques have proven invaluable for the identification of candidate genes and the advancement of functional genomics research. Nevertheless, the application of these technologies
Yonglu Wei, Zengyu Lin, Qi Xie, Jie Gao, Jianpeng Jin, Jie Li, Chuqiao Lu, Guangying Ye, Wenkang Li, Chuanfeng Huang, Dengqi Yang, Qi Liu, Genfa Zhu, Fengxi Yang   +13 more
wiley   +1 more source

Effector‐Mediated Spatial Reprogramming of Glycolate Oxidase Subverts Peroxisomal and Membrane‐Associated ROS Defences

Plant Biotechnology Journal, EarlyView.
ABSTRACT Oomycete pathogens secrete hundreds of RXLR effectors into plant cells to modulate host immunity by targeting diverse plant proteins. Here, we report that the Peronophythora litchii RXLR effector PlAvh133 acts as a virulence factor and targets the litchi glycolate oxidase (GLO) LcGLO1, a key enzyme in photorespiration, thereby suppressing ...
Junjian Situ, Zijing Zhang, Yi Shao, Jiaying Feng, Feiteng Zhong, Muran Xiong, Wen Li, Peng Li, Xiaofan Zhou, Guibing Hu, Jietang Zhao, Minhui Li, Pinggen Xi, Xinxiang Peng, Zide Jiang, Guanghui Kong   +15 more
wiley   +1 more source