Results 71 to 80 of about 191,709 (318)

Coinfection of Leishmania (Viannia) braziliensis and Streptococcus pneumoniae in multiple cutaneous lesions [PDF]

open access: yes, 2016
Key learning points Cutaneous leishmaniasis is the most common clinical disease caused by all the Leishmania species that are pathogenic to humans. Other bacterial coinfections of Leishmania lesions have been described, but this is the first report of ...
Chiapello, Laura Silvina   +6 more
core   +2 more sources

Structural and Functional Characterization of EXPO‐Derived Extracellular Vesicles in Plants

open access: yesAdvanced Science, EarlyView.
In this study, 3D electron tomography (ET), cryo‐ET, and immunogold transmission electron microscopy (TEM) are employed to characterize plant extracellular vesicles (EVs) under physiological conditions. EVs are classified into three distinct categories according to their size, content, and molecular‐marker profiles. Furthermore, Exo70E2‐positive medium
Jiayang Gao   +12 more
wiley   +1 more source

Prevalence of rifampicin resistant Mycobacterium tuberculosis among presumptive tuberculosis patients in selected governmental hospitals in Addis Ababa, Ethiopia

open access: yesBMC Infectious Diseases, 2019
BackgroundRapid detection of rifampicin resistance is essential for early management and prevention of transmission of multidrug-resistant tuberculosis (MDR-TB). We studied the prevalence of rifampicin resistance of Mycobacterium tuberculosis (MTB) among
Balew Arega, Fiqrte Menbere, Y. Getachew
semanticscholar   +1 more source

Adverse drug reactions in tuberculosis patients due to directly observed treatment strategy therapy: Experience at an outpatient clinic of a teaching hospital in the city of Imphal, Manipur, India

open access: yesThe Journal of Association of Chest Physicians, 2013
Background: As to the profile of adverse drug reactions (ADRs) due to directly observed treatment, short course (DOTS), there is no report available in patients receiving antituberculosis (anti-TB) chemotherapy in Manipur, India.
Kumarjit Sinha   +2 more
doaj   +1 more source

Chloroplast Stress Signals Orchestrate Epidermis‐Specific Remodeling of Mitochondria and ER Under High Light

open access: yesAdvanced Science, EarlyView.
High light exposure triggers an epidermis‐specific remodeling of mitochondria and ER in Arabidopsis, driven by chloroplast‐derived signals. Live‐cell imaging shows that HL rapidly suppresses mitochondrial motility, followed by fusion‐driven elongation and ER cisternal expansion.
Evan R. Angelos   +12 more
wiley   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

Prosthetic joint infections [PDF]

open access: yes, 2013
Objectives: To review the available literature on prosthetic joint infections and provide recommendations on management particularly the importance of identifying the causative organism and starting the most appropriate antimicrobial therapy.
Fsadni, Claudia, Fsadni, Peter
core  

rpoB mutations conferring rifampicin-resistance affect growth, stress response and motility in Vibrio vulnificus

open access: yesMicrobiology, 2020
Rifampicin is a broad-spectrum antibiotic that binds to the bacterial RNA polymerase (RNAP), compromising DNA transcription. Rifampicin resistance is common in several microorganisms and it is typically caused by point mutations in the gene encoding the ...
L. Cutugno   +4 more
semanticscholar   +1 more source

High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates [PDF]

open access: yes, 2019
Clostridium [Clostridioides] difficile infection (CDI) is one of the leading causes of diarrhea associated with medical care worldwide, and up to 60% of patients with CDI can develop a recurrent infection (R-CDI). A multi-species microbiota biofilm model
Baines, Simon   +9 more
core   +2 more sources

Effect of enzalutamide on anticoagulant therapy with edoxaban in patients with prostate cancer

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Treatment with enzalutamide in prostate cancer is challenging due to its high potential for drug–drug interactions, particularly in the typically older population of patients with frequent comorbidities treated with multiple drugs, such as anticoagulants.
Catharina J. P. Op 't Hoog   +8 more
wiley   +1 more source

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