Results 71 to 80 of about 156,396 (269)

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup   +2 more
wiley   +1 more source

Enhancing antimycobacterial activity of isoniazid and rifampicin incorporated norbornene nanoparticles

open access: yesInternational Journal of Mycobacteriology, 2018
Background: Tuberculosis (TB) has been identified in skeletons over 6000 years old and still remains as the most prevalent infectious disease in the world; thus, there is a need for development of new drugs or tuning of old drugs.
Kalaiselvi Kumarasingam   +5 more
doaj   +1 more source

Compounding Effects of Climate Warming and Antibiotic Resistance. [PDF]

open access: yes, 2020
Bacteria have evolved diverse mechanisms to survive environments with antibiotics. Temperature is both a key factor that affects the survival of bacteria in the presence of antibiotics and an environmental trait that is drastically increasing due to ...
Cruz-Loya, Mauricio   +4 more
core   +1 more source

Molecular characterization of resistance to Rifampicin in an emerging hospital-associated Methicillin-resistant Staphylococcus aureus clone ST228, Spain [PDF]

open access: yes, 2010
Background: Methicillin-resistant S. aureus (MRSA) has been endemic in Hospital Universitari de Bellvitge, Barcelona, since 1990. During the 1990-95 period the Iberian clone (ST-247; SCCmec-I) was dominant. Isolates of clonal complex 5 (ST-125; SCCmec-IV)
Fe Tubau   +5 more
core   +1 more source

Effect of oxycodone vs. morphine as first‐line opioid on new persistent opioid use after orthopaedic surgery: A prospective sequential cohort study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Background Postoperative opioids, intended for short‐term analgesia, contribute to new persistent opioid use in 1%–7% of patients, adversely affecting outcomes. Oxycodone may carry higher risk than morphine, though long‐term data are limited.
Eward J. Melis   +5 more
wiley   +1 more source

Functionalizing Conductive Diamond: Recent Advance in Fabrication, Modifications, and Applications

open access: yesCarbon Energy, EarlyView.
This review highlights recent advancements in the synthesis, modification, and electrochemical applications of conductive diamond, particularly boron‐doped diamond (BDD). It emphasizes progress in fabrication methods, including CVD and HPHT, and explores modifications such as doping, surface terminations, and composite design, enabling significant ...
Ning Linghu, Xin Jiang, Jing Xu
wiley   +1 more source

Fabricating and Properties of Rifampicin-loaded Ethyl Cellulose Composites Via Electrospray

open access: yesStudia Universitatis Babes-Bolyai Chemia
Rifampin (Rif) is usually applied as first-line anti-tubercular drugs but has limited bioavailability. Herein, Rif-loaded ethyl cellulose (EC) composites was designed and fabricated by electrospray to improve therapy effectiveness and duration.
Xi LI   +9 more
doaj   +1 more source

Antileprotic medication induced psychosis in a patient of tuberous sclerosis: A case report

open access: yesIndian Journal of Community and Family Medicine, 2017
Tuberous sclerosis is a rare multisystem neurocutaneous genetic disorder primarily presented with seizures, mental retardation and hamartomas involving multiple systems.
Udit Kumar Panda   +2 more
doaj   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott   +7 more
wiley   +1 more source

Efavirenz Plasma Concentrations and HIV Viral Load in HIV/AIDS-tuberculosis Infection Patients Treated with Rifampicin

open access: yesActa Medica Indonesiana, 2016
Aim:to determine the effect of a rifampicin-containing tuberculosis regimen on efavirenz plasma concentrations and viral load in HIV/AIDS-Tuberculosis infection patients who received efavirenz-based antiretroviral therapy.
Nina Mariana   +3 more
doaj  

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