Results 81 to 90 of about 156,396 (269)

A novel approach for lung delivery of rifampicin-loaded liposomes in dry powder form for the treatment of tuberculosis

open access: yesLung India, 2015
Background: Lung administration of antibiotics by nebulization is promising for improved treatment efficiency for pulmonary infections, as it increases drug concentration at sites of infection while minimizing systemic side effects.
Jagadevappa S Patil   +3 more
doaj   +1 more source

Secondary Tuberculosis of Tonsil case report and literature review [PDF]

open access: yes, 2012
A case report of secondary tuberculosis of tonsil is being discussed along with review of published literature. This report attempts to draw attention to the fact that Tuberculosis is resurgentdespite excellent chemotherapeutic drugs available.
Ramamoorthy, Geetha   +2 more
core   +1 more source

Accelerating Generic Long‐Acting Antiretrovirals for Global HIV Treatment: Workshop Findings and a Roadmap to Access

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The global HIV response aims for widespread availability of affordable, quality‐assured long‐acting antiretroviral (LA ARV) drugs to achieve sustained epidemic control, particularly in low‐ and middle‐income countries. This report summarizes key discussion points, findings, and outcomes from an international workshop on generic LA ARVs, held in ...
Usman Arshad   +22 more
wiley   +1 more source

Poor response to tuberculosis treatment with regimens without rifampicin in immunosuppressed AIDS patients

open access: yesBrazilian Journal of Infectious Diseases
A prospective study was conducted on 79 advanced immunosuppressed AIDS patients from 1997 to 1999, during which nine cases of tuberculosis (TB) were diagnosed.
M.M. O'Donnel   +6 more
doaj   +1 more source

Clinical Pharmacology Quality Assurance Program for Global HIV and Co‐Infection Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
When the acquired immunodeficiency syndrome emerged in the 1980s, the United States National Institutes of Health established research networks to conduct clinical trials with the pharmaceutical industry to identify effective antiretroviral therapeutics.
Robin DiFrancesco   +17 more
wiley   +1 more source

Detection of multidrug resistant Mycobacterium tuberculosis in Tabuk, Saudi Arabia, using Genotype MTBDRplus

open access: yesInternational Journal of Mycobacteriology, 2019
Background: The global increase in the rates of multidrug-resistant (MDR) tuberculosis (TB) has made the timely identification of resistant Mycobacterium tuberculosis complex strains an important emergence to achieve effective disease management and to ...
Eltayib Hassan Ahmed-Abakur   +1 more
doaj   +1 more source

Antituberculosis Activity of Brotowali (Tinospora Crispa) Extract and Fractions Against Mycobacterium Tuberculosis Using Microplate Alamar Blue Assay Method [PDF]

open access: yes, 2017
Tuberculosis (TB), in which caused by pathogenic bacteria, Mycobacterium tuberculosis, has become the major causes of death among all of infectious diseases.
Irianti, T. (Tatang)   +5 more
core  

Virological outcomes of second-line protease inhibitor-based treatment for human immunodeficiency virus type 1 in a high-prevalence rural South African setting: a competing-risks prospective cohort analysis [PDF]

open access: yes, 2017
Background. Second-line antiretroviral therapy (ART) based on ritonavir-boosted protease inhibitors (bPIs) represents the only available option after first-line failure for the majority of individuals living with human immunodeficiency virus (HIV ...
2LADY Study Group   +22 more
core   +3 more sources

Hypervalent Iodine‐Mediated Synthesis of Sulfones Using Organozinc Pivalates and Sulfinate Salts

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A general protocol for sulfone synthesis via sulfonyl‐containing hypervalent iodine reagents and organozinc pivalates is described. The method is practical, provides a broad scope of sulfone in moderate to high yield. bicyclo[1.1.1]pentane‐sulfones are also disclosed and a one‐pot synthesis of Diels–Alder adduct is presented. Sulfones are key motifs in
José C. Cunha   +4 more
wiley   +1 more source

Multi-Fluorescence Real-Time PCR Assay for Detection of RIF & INH Resistance of M. tuberculosis

open access: yesFrontiers in Microbiology, 2016
Background: Failure to early detect multidrug-resistant tuberculosis (MDR-TB) results in treatment failure and poor clinical outcomes, and highlights the need to rapidly detect resistance to rifampicin (RIF) and isoniazid (INH)Methods: In Multi ...
Jingfu ePeng   +11 more
doaj   +1 more source

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