Results 1 to 10 of about 246,146 (311)
KCNQ1OT1: An Oncogenic Long Noncoding RNA [PDF]
Biomolecules, 2021 Long noncoding RNAs (lncRNAs) are transcripts greater than 200 nucleotides that do not code for proteins but regulate gene expression. Recent studies indicate that lncRNAs are involved in the modulation of biological functions in human disease.
Patrice Cagle +3 more
doaj +4 more sources
Identification of Potentially Functional Circular RNA/Long Noncoding RNA-MicroRNA-mRNA Regulatory Networks Associated with Vascular Injury in Type 2 Diabetes Mellitus by Integrated Microarray Analysis. [PDF]
J Diabetes Res, 2023 This research is aimed at figuring out the potential circular RNA (circRNA)/long noncoding RNA- (lncRNA-) microRNA- (miRNA-) mRNA regulatory networks associated with a vascular injury in type 2 diabetes mellitus (T2DM).
Leng Y, Wang MZ, Xie KL, Cai Y, Cai Y.
europepmc +2 more sources
LINC00467: an oncogenic long noncoding RNA
Cancer Cell International, 2022 Long non-coding RNAs (lncRNAs) have been found to play essential roles in the cell proliferation, fission and differentiation, involving various processes in humans.
Xuyu Chen +6 more
doaj +3 more sources
Long noncoding RNA involvement in cancer [PDF]
BMB Reports, 2012 Recent advances in genome and transcriptome analysis haveenabled identification of numerous members of a new class ofnoncoding RNA, long noncoding RNA (lncRNA).
Reo Maruyama & Hiromu Suzuki*
doaj +4 more sources
Human and Experimental Toxicology, 2023 Background Long intergenic non-protein-coding RNA 173 (LINC00173) executes vital functions in various cancers. Nevertheless, its role and expression in nasopharyngeal carcinoma (NPC) have yet to be investigated.
Dan Wang, Heng Jiang
semanticscholar +1 more source
Long noncoding RNA turnover [PDF]
Biochimie, 2015 Most RNAs transcribed in mammalian cells lack protein-coding sequences. Among them is a vast family of long (>200 nt) noncoding (lnc)RNAs. LncRNAs can modulate cellular protein expression patterns by influencing the transcription of many genes, the post-transcriptional fate of mRNAs and ncRNAs, and the turnover and localization of proteins.
Je-Hyun, Yoon +2 more
openaire +2 more sources
Long noncoding RNA: noncoding and not coded [PDF]
Cell Death Discovery, 2017 Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra +2 more
openaire +2 more sources
Neural Regeneration Research, 2022 During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma +14 more
doaj +1 more source
Autophagy, 2021 Chemotherapy is currently the main treatment for unresectable or advanced postoperative gastric cancers. However, its efficacy is negatively affected by the occurrence of chemoresistance, which severely affects patient prognosis.
Yuhao Luo +13 more
semanticscholar +1 more source
The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization
Mediators of Inflammation, 2023 Macrophages are a type of immune cells with high levels of plasticity and heterogeneity. They can polarize into M1 or M2 functional phenotypes. These two phenotypes exhibit a dynamic balance during polarization-related diseases and play opposing roles ...
Xiaomin Liao +9 more
doaj +1 more source