Results 1 to 10 of about 162,179 (208)
KCNQ1OT1: An Oncogenic Long Noncoding RNA [PDF]
Biomolecules, 2021 Long noncoding RNAs (lncRNAs) are transcripts greater than 200 nucleotides that do not code for proteins but regulate gene expression. Recent studies indicate that lncRNAs are involved in the modulation of biological functions in human disease.
Patrice Cagle +3 more
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LINC00467: an oncogenic long noncoding RNA
Cancer Cell International, 2022 Long non-coding RNAs (lncRNAs) have been found to play essential roles in the cell proliferation, fission and differentiation, involving various processes in humans.
Xuyu Chen +6 more
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Long noncoding RNA involvement in cancer [PDF]
BMB Reports, 2012 Recent advances in genome and transcriptome analysis haveenabled identification of numerous members of a new class ofnoncoding RNA, long noncoding RNA (lncRNA).
Reo Maruyama & Hiromu Suzuki*
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Long noncoding RNA turnover [PDF]
Biochimie, 2015 Most RNAs transcribed in mammalian cells lack protein-coding sequences. Among them is a vast family of long (>200 nt) noncoding (lnc)RNAs. LncRNAs can modulate cellular protein expression patterns by influencing the transcription of many genes, the post-transcriptional fate of mRNAs and ncRNAs, and the turnover and localization of proteins.
Je-Hyun, Yoon +2 more
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Long noncoding RNA: noncoding and not coded [PDF]
Cell Death Discovery, 2017 Mammalian evolution exhibits extraordinary acceleration in phenotypic complexity while displaying genetic conservation. Indeed, protein-coding genes are 90% identical between mice and human, and the question arises what might be the mechanisms by which phenotypic complexity increases while the number of proteins does not?
Toiber, Debra +2 more
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Neural Regeneration Research, 2022 During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma +14 more
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The Long Noncoding RNA Gm9866/Nuclear Factor-κB Axis Promotes Macrophage Polarization
Mediators of Inflammation, 2023 Macrophages are a type of immune cells with high levels of plasticity and heterogeneity. They can polarize into M1 or M2 functional phenotypes. These two phenotypes exhibit a dynamic balance during polarization-related diseases and play opposing roles ...
Xiaomin Liao +9 more
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The Landscape of Noncoding RNA in Pulmonary Hypertension
Biomolecules, 2022 The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding RNA transcripts playing crucial roles.
Lin Deng +4 more
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Non‐coding RNA and cholesteatoma
Laryngoscope Investigative Otolaryngology, 2022 Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master ...
Ivan Jovanovic +3 more
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Technology in Cancer Research & Treatment, 2020 Objective: Our study aimed to investigate the correlation of long noncoding RNA maternally expressed gene 3 expression with clinical features, treatment response, and survival profiles in patients with acute myeloid leukemia. Methods: Bone marrow samples
Chunling He MM +4 more
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