Results 11 to 20 of about 246,146 (311)

The Landscape of Noncoding RNA in Pulmonary Hypertension

open access: yesBiomolecules, 2022
The transcriptome of pulmonary hypertension (PH) is complex and highly genetically heterogeneous, with noncoding RNA transcripts playing crucial roles.
Lin Deng   +4 more
doaj   +1 more source

Non‐coding RNA and cholesteatoma

open access: yesLaryngoscope Investigative Otolaryngology, 2022
Objective Cholesteatoma is a challenging chronic pathology of the middle ear for which pharmacologic therapies have not been developed yet. Cholesteatoma occurrence depends on the interplay between genetic and environmental factors while master ...
Ivan Jovanovic   +3 more
doaj   +1 more source

Long Noncoding RNA Maternally Expressed Gene 3 Is Downregulated, and Its Insufficiency Correlates With Poor-Risk Stratification, Worse Treatment Response, as Well as Unfavorable Survival Data in Patients With Acute Myeloid Leukemia

open access: yesTechnology in Cancer Research & Treatment, 2020
Objective: Our study aimed to investigate the correlation of long noncoding RNA maternally expressed gene 3 expression with clinical features, treatment response, and survival profiles in patients with acute myeloid leukemia. Methods: Bone marrow samples
Chunling He MM   +4 more
doaj   +1 more source

Long Noncoding RNA LUCAT1 Promotes Multiple Myeloma Cell Growth by Regulating the TGF-β Signaling Pathway

open access: yesTechnology in Cancer Research & Treatment, 2020
Objective: Long noncoding RNAs (lncRNAs) are potential biomarkers for cancers. Nevertheless, the ability of long noncoding RNA lung cancer-associated transcript 1 in patients with multiple myeloma remains unknown. The purpose of this current study was to
Zhaoyu Liu MM   +3 more
doaj   +1 more source

Circular Intronic Long Noncoding RNAs [PDF]

open access: yesMolecular Cell, 2013
We describe the identification and characterization of circular intronic long noncoding RNAs in human cells, which accumulate owing to a failure in debranching. The formation of such circular intronic RNAs (ciRNAs) can be recapitulated using expression vectors, and their processing depends on a consensus motif containing a 7 nt GU-rich element near the
Zhang, Yang   +8 more
openaire   +2 more sources

Knockdown of lncRNA OGFRP1 Inhibits Proliferation and Invasion of JEG-3 Cells Via AKT/mTOR Pathway

open access: yesTechnology in Cancer Research & Treatment, 2020
Increasing evidence indicates the pivotal role of long noncoding RNAs in a variety of cancers, but there is limited focus on the link between long noncoding RNAs and gestational choriocarcinoma.
Qian Meng BD, Haiyan Xue MD
doaj   +1 more source

Dysregulation of lncRNAs in circulation of patients with periodontitis: results of a pilot study

open access: yesBMC Oral Health, 2021
Background Periodontitis is a chronic inflammatory disorder with a complex etiology. Long non-coding RNAs (lncRNAs) have been shown to affect pathoetiology of periodontitis.
Soudeh Ghafouri-Fard   +7 more
doaj   +1 more source

Long noncoding RNA study: Genome-wide approaches

open access: yesGenes and Diseases, 2023
Long noncoding RNAs (lncRNAs) have been confirmed to play a crucial role in various biological processes across several species. Though many efforts have been devoted to the expansion of the lncRNAs landscape, much about lncRNAs is still unknown due to ...
Shuang Tao   +6 more
doaj   +1 more source

Long Noncoding RNAs

open access: yesJournal of the American College of Cardiology, 2016
Recent studies suggest that the majority of the human genome is transcribed, but only about 2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a heterogenic class of RNAs that includes, for example, intergenic lncRNAs, antisense transcripts, and enhancer RNAs.
Boon, Reinier A   +3 more
openaire   +3 more sources

Long noncoding RNAs and atherosclerosis [PDF]

open access: yesAtherosclerosis, 2016
Atherosclerosis is universally recognized as a chronic lipid-induced inflammation of the vessel wall in response to dyslipidemia and haemodynamic stress involving dysfunction and activation of resident vascular cells as well as infiltration of leukocytes.
Tian Zhou   +3 more
openaire   +2 more sources

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