Results 11 to 20 of about 498,663 (149)
Nucleoporins shape germ granule architecture and balance small RNA silencing pathways [PDF]
Nature CommunicationsAnimals use small RNA pathways, such as PIWI-interacting RNA (piRNA) and small interfering RNA (siRNA), to silence harmful genetic elements. In Caenorhabditis elegans, piRNA pathway components are organized into sub-compartments within germ granules near
Kun Shi +7 more
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U2.3 Precursor Small Nuclear RNA in vitro Processing Assay
Bio-Protocol, 2021 Small nuclear RNAs (snRNAs) are vital for eukaryotic cell activities and play important roles in pre-mRNA splicing. The molecular mechanism underlying the transcription of snRNA, regulated via upstream/downstream cis-elements and relevant trans-elements,
Chan Lin +5 more
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Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis
Frontiers in Molecular Biosciences, 2023 Introduction: The anterior cruciate ligament (ACL) is susceptible to degeneration, resulting in joint pain, reduced mobility, and osteoarthritis development.
Yalda A. Kharaz +6 more
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Non-Coding RNA, 2023 Traditionally, small molecule-based drug discovery has mainly focused on proteins as the drug target. Opening RNA as an additional target space for small molecules offers the possibility to therapeutically modulate disease-driving non-coding RNA targets ...
Nina Zablowsky +8 more
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Identification of small RNA in polyhedra of Bombyx mori nuclear polyhedrosis virus [PDF]
The Ukrainian Biochemical Journal, 2014 It has been shown by bioinformatic methods that regions of the Bombyx mori viral nuclear polyhedrosis genome encoded two small RNA – snc RNA-1 and snc RNA-2, which could perform a structural function in polyhedra crystals formation.
T. V. Shirina +3 more
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Journal of Ovarian Research, 2021 Nuclear small RNAs have emerged as an important subset of non-coding RNA species that are capable of regulating gene expression. A type of small RNA, microRNA (miRNA) have been shown to regulate development of the ovarian follicle via canonical targeting
Derek Toms +3 more
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RNAi Factors Are Present and Active in Human Cell Nuclei
Cell Reports, 2014 RNAi is widely appreciated as a powerful regulator of mRNA translation in the cytoplasm of mammalian cells. However, the presence and activity of RNAi factors in the mammalian nucleus has been the subject of considerable debate.
Keith T. Gagnon +4 more
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Species Diversity and Molecular Phylogeny of Cyanosporus (Polyporales, Basidiomycota)
Frontiers in Microbiology, 2021 Cyanosporus is a cosmopolitan brown-rot fungal genus, recognizable by blue-tinted basidiocarps. Species in this genus were usually treated as belonging to the Postia caesia complex, however, recent phylogenetic analyses showed that this complex ...
Shun Liu +9 more
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Intersection of small RNA pathways in Arabidopsis thaliana sub-nuclear domains. [PDF]
PLoS ONE, 2013 In Arabidopsis thaliana, functionally diverse small RNA (smRNA) pathways bring about decreased RNA accumulation of target genes via several different mechanisms.
Olga Pontes +5 more
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Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription
Cell Reports, 2017 In the cytoplasm, small RNAs can control mammalian translation by regulating the stability of mRNA. In the nucleus, small RNAs can also control transcription and splicing.
Jessica A. Hicks +6 more
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