Results 41 to 50 of about 962,124 (298)
RNA Degradation inSaccharomyces cerevisae [PDF]
Genetics, 2012 AbstractAll RNA species in yeast cells are subject to turnover. Work over the past 20 years has defined degradation mechanisms for messenger RNAs, transfer RNAs, ribosomal RNAs, and noncoding RNAs. In addition, numerous quality control mechanisms that target aberrant RNAs have been identified.
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Quantifying microbial utilization of petroleum hydrocarbons in salt-marsh sediments using the ^(13)C content of bacterial rRNA [PDF]
, 2007 Natural remediation of oil spills is catalyzed by complex microbial consortia. Here we take a whole-community approach to investigate bacterial incorporation of petroleum hydrocarbons from a simulated oil spill.
Dekas, Anne E. +5 more
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Two degrading decades for RNA [PDF]
RNA, 2015 The last 20 years have seen an explosion of discoveries in the field of RNA research. Having obtained my PhD working on group II intron self-splicing, and given the mechanistic relationships between these introns and spliceosome-mediated splicing, I feel that one of the most remarkable achievements in the last two decades was the demonstration that RNA
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RNA-seq: impact of RNA degradation on transcript quantification [PDF]
BMC Biology, 2014 The use of low quality RNA samples in whole-genome gene expression profiling remains controversial. It is unclear if transcript degradation in low quality RNA samples occurs uniformly, in which case the effects of degradation can be corrected via data normalization, or whether different transcripts are degraded at different rates, potentially biasing ...
Romero, IG, Pai, AA, Tung, J, Gilad, Y
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DegNorm: normalization of generalized transcript degradation improves accuracy in RNA-seq analysis
Genome Biology, 2019 RNA degradation affects RNA-seq quality when profiling transcriptional activities in cells. Here, we show that transcript degradation is both gene- and sample-specific and is a common and significant factor that may bias the results in RNA-seq analysis ...
Bin Xiong +3 more
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To translate, or not to translate: viral and host mRNA regulation by interferon-stimulated genes. [PDF]
, 2015 Type I interferon (IFN) is one of the first lines of cellular defense against viral pathogens. As a result of IFN signaling, a wide array of IFN-stimulated gene (ISG) products is upregulated to target different stages of the viral life cycle.
Li, Melody MH +2 more
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BMC Genomics, 2011 Background RNA degradation is critical to the survival of all cells. With increasing evidence for pervasive transcription in cells, RNA degradation has gained recognition as a means of regulating gene expression.
Williams Christopher W +1 more
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The Exosome Complex in Health and Disease: A Multifaceted Regulator of RNA Homeostasis
ExperimedThe RNA exosome complex is a multi-subunit ribonuclease complex that participates in RNA degradation, processing, and quality control. In recent years, mutations and dysregulation in the subunits of this complex, which play significant roles in RNA ...
Esra Nur Demirtaş +1 more
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The 5'-3' exoribonuclease pacman is required for epithelial sheet sealing in Drosophila and genetically interacts with the phosphatase puckered [PDF]
, 2008 Background information. Ribonucleases have been well studied in yeast and bacteria, but their biological significance to developmental processes in multicellular organisms is not well understood.
Browne, Cathy +7 more
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Insects, 2021 DsRNA-degrading enzymes (dsRNases) have been recognized as important factors in reducing RNA interference (RNAi) efficiency in different insect species. However, dsRNases in Plutella xylostella are still unknown.
Jin-Zhi Chen +5 more
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