Results 31 to 40 of about 962,124 (298)
RNA Degradation in Neurodegenerative Disease [PDF]
Ribonucleic acid (RNA) homeostasis is dynamically modulated in response to changing physiological conditions. Tight regulation of RNA abundance through both transcription and degradation determines the amount, timing, and location of protein translation.
Kaitlin, Weskamp, Sami J, Barmada
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Why Does Insect RNA Look Degraded? [PDF]
The integrity of extracted ribonucleic acid (RNA) is commonly assessed by gel electrophoresis and subsequent analysis of the ribosomal RNA (rRNA) bands. Using the honey bee, Apis mellifera (Hymenoptera: Apidae), as an example, the electrophoretic rRNA profile of insects is explained.
Winnebeck, Eva C. +2 more
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Ammonium tetrathiomolybdate (ATTM) has been used in breast cancer therapy for copper chelation, as elevated copper promotes tumor growth. ATTM is also an identified H2S donor and endogenous H2S facilitates VitB12-induced S-adenosylmethionine (SAM ...
Xiang Li +20 more
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Post-mortem Interval and Its Relation with the RNA Degradation in the Dental Pulp in Submerged Teeth
Post-mortem interval is the time between death and the discovery of the body or human remains. Teeth are the most resistant structures of the human body, able to withstand extreme conditions such as high temperature, humidity, and post-mortem degradation.
Bruna S. Borges +3 more
doaj +1 more source
Tabu Search for the RNA Partial Degradation Problem
In recent years, a growing interest has been observed in research on RNA (ribonucleic acid), primarily due to the discovery of the role of RNA molecules in biological systems.
Rybarczyk Agnieszka +3 more
doaj +1 more source
RNA Surveillance by the Nuclear RNA Exosome: Mechanisms and Significance
The nuclear RNA exosome is an essential and versatile machinery that regulates maturation and degradation of a huge plethora of RNA species. The past two decades have witnessed remarkable progress in understanding the whole picture of its RNA substrates ...
Koichi Ogami +2 more
doaj +1 more source
Target RNAs strike back on MicroRNAs [PDF]
MicroRNAs are extensively studied regulatory non-coding small RNAs that silence animal genes throughout most biological processes, typically doing so by binding to partially complementary sequences within target RNAs.
de la Mata, Manuel +3 more
core +1 more source
Messenger RNA Degradation in Bacterial Cells [PDF]
mRNA degradation is an important mechanism for controlling gene expression in bacterial cells. This process involves the orderly action of a battery of cellular endonucleases and exonucleases, some universal and others present only in certain species. These ribonucleases function with the assistance of ancillary enzymes that covalently modify the 5′ or
Monica P, Hui +2 more
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Viruses and the cellular RNA decay machinery. [PDF]
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core +1 more source
Rapid degradation of polyadenylated oop RNA [PDF]
The oop RNA is a short (77 nucleotides (nt)) transcript encoded by bacteriophage λ which acts as an antisense RNA for λ cII gene expression. Recently we demonstrated that oop RNA is specifically polyadenylated at its 3′ end by poly(A) polymerase I (PAP I), the pcnB gene product. Here we demonstrate that the half life of oop RNA is 3 times longer in the
Szalewska-Pałasz, Agnieszka +2 more
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