Results 31 to 40 of about 5,666,730 (325)
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism [PDF]
, 2010 For a long time it has been assumed that the decay of RNA in eukaryotes is mainly carried out by exoribonucleases, which is in contrast to bacteria, where endoribonucleases are well documented to initiate RNA degradation.
Tomecki, Rafał, Dziembowski, Andrzej
core +3 more sources
A model explaining mRNA level fluctuations based on activity demands and RNA age.
PLoS Computational Biology, 2021 Cellular RNA levels typically fluctuate and are influenced by different transcription rates and RNA degradation rates. However, the understanding of the fundamental relationships between RNA abundance, environmental stimuli, RNA activities, and RNA age ...
Zhongneng Xu, Shuichi Asakawa
doaj +1 more source
RNA Quality Control Using External Standard RNA [PDF]
Polish Journal of Microbiology, 2018 In this paper, we propose a new evaluation method using external standard RNA for quality control of the extracted RNA. RNA Integrity Number and UV absorption are generally used as a basis for RNA quality control; however, these methods do not always ...
HITOSHI IWAHASHI +2 more
doaj +1 more source
SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome
RNA Biology, 2023 Nsp1 is a SARS-CoV-2 host shutoff factor that both represses cellular translation and promotes host RNA decay. However, it is unclear how these two activities are connected and interact with normal translation processes.
Soraya I. Shehata, Roy Parker
doaj +1 more source
Regulation of miRNA content. Part 2. Degradation of miRNAs
Zdorovʹe Rebenka, 2021 The scientific review presents the process of regulation of microRNA content — microRNA degradation. To write the article, information was searched using databases Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The ...
A.E. Abaturov, V.L. Babуch
doaj +1 more source
Maf1-mediated repression of RNA polymerase III transcription inhibits tRNA degradation via RTD pathway [PDF]
, 2012 tRNA precursors, which are transcribed by RNA polymerase III, undergo end-maturation, splicing and base modifications. Hypomodified tRNAs, such as tRNAVal(AAC), lacking 7-methylguanosine and 5-methylcytidine modifications, are subject to degradation by a
Boguta, Magdalena +3 more
core +1 more source
Frontiers in Oncology, 2020 Ammonium tetrathiomolybdate (ATTM) has been used in breast cancer therapy for copper chelation, as elevated copper promotes tumor growth. ATTM is also an identified H2S donor and endogenous H2S facilitates VitB12-induced S-adenosylmethionine (SAM ...
Xiang Li +20 more
doaj +1 more source
RNA-specific ribonucleotidyl transferases [PDF]
, 2007 RNA-specific nucleotidyl transferases (rNTrs) are a diverse family of template-independent polymerases that add ribonucleotides to the 3'-ends of RNA molecules.
Keller, W. +3 more
core +1 more source
Ribosomal RNA degradation induced by the bacterial RNA polymerase inhibitor rifampicin. [PDF]
RNA, 2021 International audienceRifampicin, a broad-spectrum antibiotic, inhibits bacterial RNA polymerase. Here we show that rifampicin treatment of Escherichia coli results in a 50% decrease in cell size due to a terminal cell division.
Hamouche L, Poljak L, Carpousis AJ.
europepmc +2 more sources