Results 261 to 270 of about 503,240 (288)

The chemical diversity of RNA modifications

Biochemical Journal, 2019
Abstract Nucleic acid modifications in DNA and RNA ubiquitously exist among all the three kingdoms of life. This trait significantly broadens the genome diversity and works as an important means of gene transcription regulation. Although mammalian systems have limited types of DNA modifications, over 150 different RNA modification types ...
R. Jordan Ontiveros, Julian Stoute, Kathy Fange Liu   +2 more
openaire   +2 more sources

Catalysts for RNA and DNA modification

Current Opinion in Chemical Biology, 2015
To study DNAs and RNAs it is often necessary to chemically modify them. Nature's strategy for nucleic acid modification is to use selective catalysts, and chemists have begun to emulate this conceptual approach. In this review we present a summary of catalytic approaches toward the construction of modified RNAs and DNAs and outline our opinions on ...
Gillingham, Dennis, Shahid, Ramla
openaire   +3 more sources

Advances in the detection of RNA modification

Chemical Communications
Herein, a comprehensive overview of state-of-the-art techniques for identifying RNA modifications is presented, including high-throughput sequencing technologies and locus-specific approaches.
Ruiqi Zhao, Xin Fang, Xiaocheng Weng
openaire   +2 more sources

Sequencing diverse RNA modifications

Nature Methods, 2021
Nanopore sequencing enables quantitative profiling of pseudouridine and 2′-O-methylation modifications in native RNAs.
openaire   +2 more sources

TRANSFER RNA MODIFICATION

Annual Review of Biochemistry, 1987
G R, Björk, J U, Ericson, C E, Gustafsson, T G, Hagervall, Y H, Jönsson, P M, Wikström   +5 more
openaire   +2 more sources

The Diversity and Functions of Plant RNA Modifications: What We Know and Where We Go from Here

Annual Review of Plant Biology, 2023
Wil Prall, Garima Bhatia, Brian D Gregory   +2 more
exaly  

Identification of differential RNA modifications from nanopore direct RNA sequencing with xPore

Nature Biotechnology, 2021
Ploy N Pratanwanich, Ying Chen, Wee Joo Chng   +2 more
exaly  

RNA modifications as emerging therapeutic targets

Wiley Interdisciplinary Reviews RNA, 2022
Akin Çayır
exaly  

RNA Modifications

2021
openaire   +1 more source

Navigating the pitfalls of mapping DNA and RNA modifications

Nature Reviews Genetics, 2023
Yimeng Kong, Edward A Mead, Gang Fang
exaly