Circadian rhythms and post-transcriptional regulation in higher plants [PDF]
Frontiers in Plant Science, 2015 The circadian clock of plants allows them to cope with daily changes in their environment. This is accomplished by the rhythmic regulation of gene expression, in a process that involves many regulatory steps.
Andres eRomanowski +1 more
doaj +6 more sources
Structural and functional organization of RNA regulons in the post-transcriptional regulatory network of yeast [PDF]
Nucleic Acids Research, 2011 Post-transcriptional control of mRNA transcript processing by RNA binding proteins (RBPs) is an important step in the regulation of gene expression and protein production.
A. Joshi, Y. Van de Peer, T. Michoel
semanticscholar +4 more sources
Transfer RNA Post-Transcriptional Processing, Turnover, and Subcellular Dynamics in the YeastSaccharomyces cerevisiae [PDF]
Genetics, 2013 AbstractTransfer RNAs (tRNAs) are essential for protein synthesis. In eukaryotes, tRNA biosynthesis employs a specialized RNA polymerase that generates initial transcripts that must be subsequently altered via a multitude of post-transcriptional steps before the tRNAs beome mature molecules that function in protein synthesis.
A. Hopper
openaire +4 more sources
Can we always sweep the details of RNA-processing under the carpet? [PDF]
, 2013 RNA molecules follow a succession of enzyme-mediated processing steps from transcription until maturation. The participating enzymes, for example the spliceosome for mRNAs and Drosha and Dicer for microRNAs, are also produced in the cell and their copy-numbers fluctuate over time.
Berg, Johannes +2 more
arxiv +3 more sources
Human sat III and Drosophila hsrω transcripts: a common paradigm for regulation of nuclear RNA processing in stressed cells [PDF]
Nucleic Acids Research, 2006 Exposure of cells to stressful conditions elicits a highly conserved defense mechanism termed the heat shock response, resulting in the production of specialized proteins which protect the cells against the deleterious effects of stress.
C. Jolly, S. C. Lakhotia
semanticscholar +7 more sources
A genome-wide tethering screen reveals novel potential post-transcriptional regulators in Trypanosoma brucei. [PDF]
PLoS Pathogens, 2014 In trypanosomatids, gene expression is regulated mainly by post-transcriptional mechanisms, which affect mRNA processing, translation and degradation. Currently, our understanding of factors that regulate either mRNA stability or translation is rather ...
Esteban D Erben +4 more
doaj +2 more sources
Role of Sam68 in Post-Transcriptional Gene Regulation [PDF]
International Journal of Molecular Sciences, 2013 The STAR family of proteins links signaling pathways to various aspects of post-transcriptional regulation and processing of RNAs. Sam68 belongs to this class of heteronuclear ribonucleoprotein particle K (hnRNP K) homology (KH) single domain-containing ...
F. Sánchez-Jiménez +1 more
semanticscholar +4 more sources
RNA Metabolism and the Role of Small RNAs in Regulating Multiple Aspects of RNA Metabolism. [PDF]
Noncoding RNARNA metabolism is focused on RNA molecules and encompasses all the crucial processes an RNA molecule may or will undergo throughout its life cycle. It is an essential cellular process that allows all cells to function effectively.
Dawar P, Adhikari I, Mandal SN, Jayee B.
europepmc +2 more sources
PLoS ONE, 2014 Cyclin-dependent kinases (CDKs) are key regulators of the cell cycle and RNA polymerase II mediated transcription. Several pharmacological CDK inhibitors are currently in clinical trials as potential cancer therapeutics and some of them also exhibit antiviral effects.
Holčáková, J. +8 more
openaire +6 more sources