Results 251 to 260 of about 287,328 (279)

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

Mechanical Processing of Lipoaspirate With a Fluidic Device Platform Promotes Wound Healing Transcriptional Programs and Angiogenesis In Vitro. [PDF]

Aesthet Surg J
Lombardo JA, Banyard DA, Zalazar D, Ziegler M, Sorensen AM, Phummirat P, Widgerow AD, Haun JB.   +7 more
europepmc   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

Advanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania, Manus J. P. Biggs, Katarzyna Krukiewicz   +2 more
wiley   +1 more source

Pre-mRNA Splicing Functions in Plant Sexual Reproduction Development. [PDF]

Plants (Basel)
Shao D, Gao X, Wei Y.
europepmc   +1 more source

Association of RDoC dimensions with <i>post mortem</i> brain transcriptional profiles in Alzheimer's disease. [PDF]

Alzheimers Dement (Amst)
Jiang W, Vogelgsang J, Dan S, Durning P, McCoy TH, Berretta S, Klengel T.   +6 more
europepmc   +1 more source

Multipurpose RNA maturation factors dysregulate multiple mRNA processing steps simultaneously and provide new therapeutic opportunities. [PDF]

RNA Biol
Paira S, Borden KLB.
europepmc   +1 more source

Beyond Chaperoning: The Multifaceted Role of FACT in Chromatin Transactions. [PDF]

Int J Mol Sci
Volokh O, Studitsky VM, Sokolova OS.
europepmc   +1 more source

Specialised RNA decay fine-tunes monogenic antigen expression in African trypanosomes

Lansink LIM, Walther L, Longmore S, Jones M, Dowle A, Faria JRC.   +5 more
europepmc   +1 more source

Nuclear-activating miRNAs: unveiling the intricacies of subcellular miRNA function and regulation in cancer and immunity disease. [PDF]

Cancer Cell Int
Ren X, Liu G, Zhou J.
europepmc   +1 more source

Maternal Western-style diet has a persistent effect on offspring gene expression in skeletal muscle of Japanese macaques. [PDF]

Sci Rep
Beck EA, Hetrick B, Nassar L, Turnbull DW, Dean TA, Takahashi DL, Gannon M, Wesolowski SR, Aagaard KM, Friedman JE, Kievit P, McCurdy CE.   +11 more
europepmc   +1 more source