Results 51 to 60 of about 365,508 (294)
Evolution of ribonuclease H genes in prokaryotes to avoid inheritance of redundant genes
BMC Evolutionary Biology, 2007 Background A theoretical model of genetic redundancy has proposed that the fates of redundant genes depend on the degree of functional redundancy, and that functionally redundant genes will not be inherited together.
Tomita Masaru +2 more
doaj +1 more source
Caractérisation de la RNase E et du dégradosome d'ARN de la bactérie marine adaptée au froid Pseudoalteromonas haloplanktis [PDF]
, 2010 La dégradation des ARNm est l'un des processus biologiques essentiels qui implique chez les bactéries, l'intervention d'un complexe multiprotéique appelé « dégradosome d'ARN ».
Ait-Bara, Soraya
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Вавиловский журнал генетики и селекции, 2014 Pathogenesis-related (PR) proteins participate in complex plant defense response to pathogens. It is known that members of two PR-proteins families (PR-4 and PR-10) exhibit ribonuclease activity in some cases.
E. A. Filipenko +4 more
doaj
The Scientific World Journal, 2014 Many flowering plants exhibit an important intraspecific reproductive barrier phenomenon, that is, self-incompatibility (SI), in which S-RNase genes play a significant role.
Lin Zhang +8 more
doaj +1 more source
Ribonuclease E modulation of the bacterial SOS response. [PDF]
PLoS ONE, 2012 Plants, animals, bacteria, and Archaea all have evolved mechanisms to cope with environmental or cellular stress. Bacterial cells respond to the stress of DNA damage by activation of the SOS response, the canonical RecA/LexA-dependent signal transduction
Robert Manasherob +3 more
doaj +1 more source
Identity of the RNase MRP– and RNase P–associated Th/To autoantigen [PDF]
Arthritis & Rheumatism, 2002 AbstractObjectiveTo characterize the molecular identity of the Th/To autoantigen, which is targeted by autoantibodies in scleroderma and which is associated with the human RNase MRP and RNase P ribonucleoprotein complexes.MethodsProteins immunoprecipitated by anti‐Th/To+ patient antisera from biotinylated total HeLa cell extracts were analyzed by ...
Eenennaam, H. van +5 more
openaire +3 more sources
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Human RNase 7: a new cationic ribonuclease of the RNase A superfamily [PDF]
Nucleic Acids Research, 2003 Here we report on the expression and function of RNase 7, one of the final RNase A superfamily ribonucleases identified in the human genome sequence. The human RNase 7 gene is expressed in various somatic tissues including the liver, kidney, skeletal muscle and heart.
Jianzhi, Zhang +2 more
openaire +2 more sources
Decrease in gyrase A protein expression in _E. coli_ cells inhibited by antisense ribozymes [PDF]
, 2008 RNase P complexed with external guide sequence (EGS) represents a novel nucleic-acid-based gene interference approach to modulate gene expression. Nucleic acid-based gene interference technologies represent promising strategies for specific inhibition of
Malathi Raghunathan +1 more
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