Active site constraints in the hydrolysis reaction catalyzed by bacterial RNase P: analysis of precursor tRNAs with a single 3'-S-phosphorothiolate internucleotide linkage [PDF]
Jens M. Warnecke+3 more
openalex +1 more source
Crystal structures and insights into precursor tRNA 5'-end processing by prokaryotic minimal protein-only RNase P. [PDF]
Li Y+14 more
europepmc +1 more source
CRABP2 plays a dual role in colorectal cancer: it promotes proliferation and suppresses apoptosis through the nuclear CRABP2/RB1 axis and the cytoplasmic AFG3L2/SLC25A39 axis. Meanwhile, it inhibits colorectal liver metastasis via AFG3L2/PINK1/Parkin‐mediated mitophagy.
Chuanxin Tian+14 more
wiley +1 more source
Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast [PDF]
Ambro van Hoof
openalex +1 more source
The many faces of RNA-based RNase P, an RNA-world relic. [PDF]
Phan HD+3 more
europepmc +1 more source
In the tripartite‐species model, Drosophila larvae stimulate lactate production through excreting digestion enzymes. S. marcescens population senses a cue of lactate and tends to diverge into virulent and reduced virulence subclusters with remarkable heterogeneity to metabolize carbon metabolism and counter colonization resistance, giving a fitness ...
Sheng Zhang+10 more
wiley +1 more source
Multiple substrate binding sites in the ribozyme from Bacillus subtilis RNase P.
Tao Pan, Monika Jakacka
openalex +1 more source
Inactivation of RNase P in Escherichia coli significantly changes post-transcriptional RNA metabolism. [PDF]
Mohanty BK, Kushner SR.
europepmc +1 more source
The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang+8 more
wiley +1 more source
Reduction of <i>Drosophila</i> Mitochondrial RNase P in Skeletal and Heart Muscle Causes Muscle Degeneration, Cardiomyopathy, and Heart Arrhythmia. [PDF]
Saoji M+5 more
europepmc +1 more source