Results 111 to 120 of about 424,860 (186)

Tear fluid as a novel specimen for detection of alpha-synuclein seeding activity in Parkinson’s disease

Scientific Reports
Parkinson’s disease (PD) is a clinically heterogeneous neurodegenerative disorder characterized by intraneuronal accumulation of misfolded α-synuclein.
Matteo Costanzo, Anna Ladogana, Marco Sbriccoli, Francesco Marchet, Flavia Porreca, Clara Salciccia, Michele Equestre, Gabriele Moracci, Maria Ilenia De Bartolo, Giulia Ruocco, Filippo Carlo Carlà, Antonella Conte, Giovanni Fabbrini, Daniele Belvisi, Anna Poleggi   +14 more
doaj   +1 more source

ePosters Virtual

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

Inhibitory effects in RT-QuIC screening.

, 2017
Compounds were applied to RT-QuIC reactions at 0 h (A) and 22 h (B). Each sample was performed in quadruplicate. The average ThT fluorescence value of the 2 highest readings at 72 h per well was plotted against time.
Su Yeon Kim (201244), Sol Moe Lee (3164226), Seong Soo A. An (2340751), Yeong Seon Lee (3164229), Jeongmin Lee (482745), Jae Wook Hyeon (3164232), Myung Koo Lee (1596679)   +6 more
core   +1 more source

Sensitive detection of pathological seeds of α-synuclein, tau and prion protein on solid surfaces.

PLoS Pathogens
Prions or prion-like aggregates such as those composed of PrP, α-synuclein, and tau are key features of proteinopathies such as prion, Parkinson's and Alzheimer's diseases, respectively.
Christina D Orrú, Bradley R Groveman, Andrew G Hughson, Tomás Barrio, Kachi Isiofia, Brent Race, Natalia C Ferreira, Pierluigi Gambetti, David A Schneider, Kentaro Masujin, Kohtaro Miyazawa, Bernardino Ghetti, Gianluigi Zanusso, Byron Caughey   +13 more
doaj   +1 more source

Issue Information

Brain Pathology, Volume 36, Issue 3, May 2026.
wiley   +1 more source

Taking the Best of Multicast and Unicast with Flexicast QUIC [PDF]

peer reviewedWith IP Multicast, a source can efficiently send the same information to a set of receivers attached to a multicast tree. Unfortunately, when distributing live video or large files, some receivers might be unable to join the multicast tree ...
De Coninck, Quentin, Barbette, Tom, Navarre, Louis, Bonaventure, Olivier   +3 more
core   +1 more source

An atypical case of Creutzfeldt-Jakob disease mimicking frontotemporal dementia: genotypic influence and clinical implications

BMC Geriatrics
We report an atypical case of Creutzfeldt-Jakob Disease (CJD) mimicking Frontotemporal Dementia (FTD) in a 68-year-old male. The patient initially presented with an anxious-depressive syndrome, progressing over 29 months to include dysexecutive syndrome,
Carlo Manco, Delia Righi, Barbara Pucci, Bruno Damiano, Andrea Mignarri, Nicola De Stefano, Domenico Plantone   +6 more
doaj   +1 more source

Head-to-head comparison of four cerebrospinal fluid and three plasma neurofilament light chain assays in Parkinsonism

npj Parkinson's Disease
Neurofilament light chain protein (NfL) is a valuable biomarker for the differential diagnosis between Parkinson’s disease (PD) and atypical parkinsonian disorders (APD).
Simone Baiardi, Marcello Rossi, Giulia Giannini, Angela Mammana, Barbara Polischi, Luisa Sambati, Andrea Mastrangelo, Franco Magliocchetti, Pietro Cortelli, Sabina Capellari, Giovanna Calandra Buonaura, Piero Parchi   +11 more
doaj   +1 more source

Salivary α-Synuclein RT-QuIC Correlates with Disease Severity in de novo Parkinson's Disease. [PDF]

Mov Disord, 2023
Vivacqua G, Mason M, De Bartolo MI, Węgrzynowicz M, Calò L, Belvisi D, Suppa A, Fabbrini G, Berardelli A, Spillantini M.   +9 more
europepmc   +1 more source

Misfolded α-Synuclein Assessment in the Skin and CSF by RT-QuIC in Isolated REM Sleep Behavior Disorder. [PDF]

Neurology, 2023
Iranzo A, Mammana A, Muñoz-Lopetegi A, Dellavalle S, Mayà G, Rossi M, Serradell M, Baiardi S, Arqueros A, Quadalti C, Perissinotti A, Ruggeri E, Cano JS, Gaig C, Parchi P.   +14 more
europepmc   +1 more source