Results 241 to 250 of about 51,464 (286)
Nature Reviews Drug Discovery, 2016 Some of the next articles are maybe not open access.
Related searches:
Related searches:
The Sarcomere and Sarcomerogenesis
2008Striated muscle owes its name to the microscopic appearance, caused by the longitudinal alignment of thousands of highly ordered contractile units, the sarcomeres. The assembly (and disassembly) of these multiprotein complexes (sarcomere assembly or sarcomerogenesis) follows ordered pathways, which are regulated on the transcriptional, translational ...
Ehler, E, Gautel, M
openaire +2 more sources
Atomistic Simulations of Sarcomere Proteins
2023Concerted atomic motions are requisite for sarcomere protein function and may become disrupted in HCM pathologies. Computational approaches such as molecular dynamics simulation can resolve such dynamics with unrivalled spatial and temporal resolution.
Matthew Carter, Childers +1 more
openaire +2 more sources
Sarcomeric Genotyping in Hypertrophic Cardiomyopathy
Mayo Clinic Proceedings, 2005To pool results from studies of patients with hypertrophic cardiomyopathy (HCM) to elucidate important phenotypic differences among genotypes.Data published from November 1998 through November 2004 were gathered and compared from unrelated study population genotyping studies from the Mayo Clinic (Rochester, Minn), Harvard Medical School (Boston, Mass),
Sara L, Van Driest +4 more
openaire +2 more sources
Inherited disorders of sarcomeric proteins
Current Opinion in Neurology, 1999The most important advances in sarcomeric protein diseases continue to be the identification of mutated genes responsible for human diseases. These have recently included those that encode skeletal muscle alpha-actin in autosomal dominant and autosomal recessive nemaline myopathy, nebulin and slow alpha-tropomyosin in autosomal recessive nemaline ...
openaire +2 more sources
Beef tenderness and sarcomere length
Meat Science, 1990A wide range of muscle glycolytic rates was produced in 60 beef carcasses by applying different forms and periods of electrical stimulation immediately after decapitation; a further seven carcasses were not stimulated. The sides were subjected to normal chilling, and at 48 h one short loin per carcass was taken for tenderness evaluation and ...
F J, Smulders +4 more
openaire +2 more sources
2010
Skeletal muscle cells, more commonly called muscle fibres, are multinucleated syncytia formed during development by fusion of mononucleated precursor cells, the myoblasts. They measure 10–100 μm in diameter and can have lengths from a few millimeters up to almost a meter.
Margit Pavelka, Jürgen Roth
openaire +1 more source
Skeletal muscle cells, more commonly called muscle fibres, are multinucleated syncytia formed during development by fusion of mononucleated precursor cells, the myoblasts. They measure 10–100 μm in diameter and can have lengths from a few millimeters up to almost a meter.
Margit Pavelka, Jürgen Roth
openaire +1 more source
Spatial sub-sarcomeric proteomic analysis reveals novel sarcomeric proteins
Journal of Molecular and Cellular Cardiology, 2022Rami Haddad +5 more
openaire +1 more source
Sarcomere Function and Crossbridge Cycling
1995The power of the heart is dictated by the force development and velocity of shortening (V) of the cardiac sarcomere. Both depend on the amount of Ca++ released by the sarcoplasmic reticulum during the action potential. We have investigated the inter-relationship between force (F) sarcomere length (SL) and V and the intracellular Ca++ concentration ([Ca+
openaire +2 more sources
Sarcomere reorganization in mite muscle
Developmental Biology, 1976Abstract The number of sarcomeres in a given muscle of the mite Tarsonemus randsi was constant in both larval and adult stages, with the exception of the two medial dorsal metapodosomal muscles in males. These muscles have three sarcomeres in larvae and one sarcomere in adults.
openaire +2 more sources