Results 11 to 20 of about 35,719 (245)
Molecular Cancer, 2023 Background Chimeric antigen receptor (CAR) -T cell therapy is an efficient therapeutic strategy for specific hematologic malignancies. However, positive outcomes of this novel therapy in treating solid tumors are curtailed by the immunosuppressive tumor ...
Jing Chen +5 more
semanticscholar +1 more source
Rapid, Point-of-Care scFv-SERS Assay for Femtogram Level Detection of SARS-CoV-2
ACS Sensors, 2022 Rapid, sensitive, on-site identification of SARS-CoV-2 infections is an important tool in the control and management of COVID-19. We have developed a surface-enhanced Raman scattering (SERS) immunoassay for highly sensitive detection of SARS-CoV-2 ...
D. Antoine +8 more
semanticscholar +1 more source
Open Life Sciences, 2022 A histidine (His)-tag is composed of six His residues and typically exerts little influence on the structure and solubility of expressed recombinant fusion proteins.
He Shuzhen +10 more
doaj +1 more source
Recombinant expression of monovalent and bivalent anti-TNT-antibodies: Evaluation of different expression systems [PDF]
Journal of the Serbian Chemical Society, 2008 Monoclonal 11B3 anti-TNT (trinitrotoluene) antibody was expressed as a monovalent and bivalent form using different prokaryotic and eukaryotic expression systems.
Simonović Mladen +3 more
doaj +1 more source
Effect of non-repetitive linker on in vitro and in vivo properties of an anti-VEGF scFv
Scientific Reports, 2022 Single chain antibody fragments (scFvs) are favored in diagnostic and therapeutic fields thanks to their small size and the availability of various engineering approaches.
Merve Arslan +5 more
semanticscholar +1 more source
Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer
OncoImmunology, 2022 Retargeting of T lymphocytes toward cancer cells by bispecific antibodies has demonstrated its therapeutic potential, with one such antibody approved for the treatment of acute lymphoblastic leukemia (blinatumomab) and several other in clinical trials ...
Antonio Tapia-Galisteo +15 more
doaj +1 more source
Novel Plantibodies Show Promise to Protect Citrus from Greening Disease
Journal of the American Society for Horticultural Science, 2021 Candidatus Liberibacter asiaticus (CLas), the bacteria responsible for citrus greening disease [huanglongbing (HLB)], has become a worldwide threat to citrus (Citrus sp.) production.
Joseph Krystel +3 more
doaj +1 more source
Successful Application of Whole Cell Panning for Isolation of Phage Antibody Fragments Specific to Differentiated Gastric Cancer Cells [PDF]
Advanced Pharmaceutical Bulletin, 2019 Purpose: Generation of antibodies which potentially discriminate between malignant and healthy cells is an important prerequisite for early diagnosis and treatment of gastric cancer (GC).
Sepideh Nikfarjam +5 more
doaj +1 more source
Scientific Reports, 2021 Single-chain variable fragments (scFvs) are small-sized artificial constructs composed of the immunoglobulin heavy and light chain variable regions connected by a peptide linker.
R. B. de Aguiar +9 more
semanticscholar +1 more source
Development of a SARS-CoV-2-specific biosensor for antigen detection using scFv-Fc fusion proteins
Biosensors & bioelectronics, 2020 Coronavirus disease 2019 (COVID-19) is a newly emerged human infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
semanticscholar +1 more source