Results 81 to 90 of about 16,421 (302)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
The Effect of Argument-Driven Inquiry on Students’ Scientific Reasoning and Argumentation Skills
Jurnal Studi Guru dan PembelajaranDeveloping students’ scientific reasoning and argumentation skills is essential for achieving meaningful learning in physics, as these competencies are fundamental to scientific literacy and higher-order thinking.
Ielda Paramita +4 more
doaj +1 more source
Eksplorasi Perbedaan Gender Pada Argumentasi Ilmiah Siswa
Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan, 2020 : Studies about neuroscience reported that women and men have differences in some parts of their brain. Women and men have different ways to encrypt memories, solve problems, and make decisions. This study aimed to explore and raise gender differences in
Nurul Atqiya +2 more
doaj +1 more source
Scientific argumentation in chemistry education: implications and suggestions
, 2018 The Malaysia Education Blueprint 2012-2025 reveals the aspiration of government to prepare Malaysian children to meet the challenges of a 21st century economy. Nonetheless, Malaysia has a long way to go to achieve this target.
Lee, Yeng Hong, Abdul Talib, Corrienna
core +1 more source
Abstract argumentation and explanation applied to scientific debates [PDF]
, 2013 argumentation has been shown to be a powerful tool within many fields such as artificial intelligence, logic and legal reasoning. In this paper we enhance Dung's well-known abstract argumentation framework with explanatory capabilities.
Seselja, Dunja, Strasser, Christian
core +1 more source
, 2023 Improving scientific reasoning and argumentation are central aims of science education. Because of their complex nature, self-regulation is important for successful scientific reasoning.
Yoana Omarchevska
core +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source