Results 51 to 60 of about 3,530 (300)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The effect of socio-scientific issue (SSI) based discussion: A student-centred approach to the teaching of argumentation

SOTL in the South, 2020
Students should have the capability to argue about controversial science issues that are relevant to them and that impact society. These controversial issues, called socio-scientific issues (SSI), are influenced by social, ethical and moral norms.
Nahid Parween Anwar, Muhammad Abid Ali
doaj   +4 more sources

ARGUMENTATION SKILLS AND SELF-REGULATION OF STUDENTS USING PROBLEM BASED LEARNING COMBINED WITH DEBATES BASED ON SOCIOSCIENTIFIC ISSUES ON ENVIRONMENTAL CHANGE MATERIAL

EDUSAINS
Lack of self-confidence and self-monitoring to think, act and communicate scientifically are related to argumentation skills. This study aimed to determine differences: (1) students' argumentation skills, (2) students' self-regulation, (3) argumentation ...
Anie Yuni Widyastuti, Harlita Harlita, Meti Indrowati   +2 more
doaj   +1 more source

Guided Inquiry Learning Model Using Scientific Argumentation Activities to Improve Concept Understanding on Optical and Light

Jurnal Pendidikan Fisika Indonesia, 2023
Problem-solving ability, as one of the most important skills in the 21st century, must be improved to face the various challenges that exist. This is because solving problems requires mastery of the concepts underlying them.
R. Rahayu, S. Siswanto, C. A. Ramadhanti, B. Subali   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Development of Teaching Material Supplements Based on Socio Scientific Issues to Improve Students' Scientific Argumentation Ability

Journal of Innovative Science Education, 2023
The impact of the Covid-19 pandemic has touched every aspect of people's lives, including health and education. Because there is a lot of ignorance about prevention of Covid-19, it is necessary to have learning media that is easily accepted.
Khairul Anam, Siti Harnina Bintari, Parmin Parmin   +2 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Mastery of Scientific Argumentation on the Concept of Neutralization in Chemistry: A Malaysian Perspective

Malaysian Journal of Learning and Instruction, 2015
Purpose – Argumentative practices are central to science education, and have recently been emphasised to promote students’ reasoning skills and to develop student’s understanding of scientific concepts.
Lee Ling Heng, Johari Surif, Cher Hau Seng, Nor Hasniza Ibrahim   +3 more
doaj   +3 more sources

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Argumentation and Knowledge Construction in Higher Education: A Vygotskian Perspective

Praxis & Saber
Empirical research indicates that the utilization of argumentation as an educational strategy fosters the acquisition of argumentation skills and disciplinary knowledge.
Ingrid González-Palta, Antonia Larrain
doaj   +1 more source