Results 51 to 60 of about 7,545,871 (284)

Skills to argue: using argument-based learning (AbL) and socio-scientific issues to promote university students’ argumentation skills in chemistry

Journal of Physics: Conference Series, 2020
AbstractSkills in making scientific argumentations are crucial for students to understand science concepts. This study had used an argument-based learning (AbL) adopting Toulmin’s Argumentation Pattern (TAP) and socio-scientific issues about heavy metals to promote the argumentation skills of the Indonesian university chemistry students.
MH Effendi-Hasibuan, A Bakar, null Harizon   +2 more
openaire   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

The effect of socio-scientific issue (SSI) based discussion: A student-centred approach to the teaching of argumentation

SOTL in the South, 2020
Students should have the capability to argue about controversial science issues that are relevant to them and that impact society. These controversial issues, called socio-scientific issues (SSI), are influenced by social, ethical and moral norms.
Nahid Parween Anwar, Muhammad Abid Ali
doaj   +4 more sources

ARGUMENTATION SKILLS AND SELF-REGULATION OF STUDENTS USING PROBLEM BASED LEARNING COMBINED WITH DEBATES BASED ON SOCIOSCIENTIFIC ISSUES ON ENVIRONMENTAL CHANGE MATERIAL

EDUSAINS
Lack of self-confidence and self-monitoring to think, act and communicate scientifically are related to argumentation skills. This study aimed to determine differences: (1) students' argumentation skills, (2) students' self-regulation, (3) argumentation ...
Anie Yuni Widyastuti, Harlita Harlita, Meti Indrowati   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Mapping Children's Discussions of Evidence in Science to Assess Collaboration and Argumentation [PDF]

, 2006
The research reported in this paper concerns the development of children's skills of interpreting and evaluating evidence in science. Previous studies have shown that school teaching often places limited emphasis on the development of these skills, which
Shirley Simon, Jane Maloney, Maloney, Jane, Simon, Shirley   +3 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Computing preferred extensions in abstract argumentation : a SAT based approach [PDF]

, 2013
This paper presents a novel SAT-based approach for the computation of extensions in abstract argumentation, with focus on preferred semantics, and an empirical evaluation of its performances.
Vallati, Mauro, Giacomin, Massimiliano, Paul E. Dunne, Cerutti, Federico, Federico Cerutti, Massimiliano Giacomin, Dunne, Paul E., Dunne, Paul, Mauro Vallati   +8 more
core   +1 more source

Profil Kemampuan Argumentasi Lisan Berbasis Socioscientific Issues Mahasiswa Pendidikan IPA pada Mata Kuliah Mikrobiologi

Pendipa, 2023
This study aims to determine the profile of students' oral argumentation skills based on Socioscientific Issues in the Microbiology course. This type of research is a descriptive study in order to obtain an overview of the quality of oral arguments of ...
Annisa Novianti Taufik, Liska Berlian, Atep Iman, Risa Tarisa   +3 more
doaj   +1 more source