Results 11 to 20 of about 3,122 (171)

Analogs of the Scorpion Venom Peptide Stigmurin: Structural Assessment, Toxicity, and Increased Antimicrobial Activity [PDF]

Toxins, 2018
Marcelo Sousa Silva, Claudia Moreno, Da Silva-Júnior A A   +2 more
exaly   +2 more sources

Animal Venom Pharmacological Resources: Exploiting Bioactive Peptides to Target Multi-Drug-Resistant Bacteria. [PDF]

Biochem Res Int
Background The escalating rise of multi–drug‐resistant (MDR) bacterial strains significantly threatens global health, creating a “silent pandemic” prompted by natural selection, gene mutation, and horizontal gene transfer. This crisis is worsened by the deficit in the development of new treatments, necessitating the innovative discovery of new potent ...
Jaber R, Mattei C, Accary C, Roufayel R, Abi Khattar Z, Fajloun Z.   +5 more
europepmc   +2 more sources

Toxinology in the proteomics era: a review on arachnid venom proteomics [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2022
The word venomics was coined to acknowledge the studies that use omics to investigate venom proteins and peptides. Venomics has evolved considerably over the last 20 years. The first works on scorpion or spider venomics were published in the early 2000’s.
Filipi Calbaizer Marchi, Edneia Mendes-Silva, Lucas Rodrigues-Ribeiro, Lucas Gabriel Bolais-Ramos, Thiago Verano-Braga   +4 more
doaj   +1 more source

Molecular Cloning and Functional Identification of the Antimicrobial Peptide Gene Ctri9594 from the Venom of the Scorpion Chaerilus tricostatus

Antibiotics, 2021
Scorpion venom is a mixture of bioactive peptides, among which neurotoxins and antimicrobial peptides serve especially vital functions. Scorpion venom peptides in Buthidae species have been well described, but toxic peptides from non-Buthidae species ...
Dangui He, Zhijian Cao, Ruhong Zhang, Wenhua Li   +3 more
doaj   +1 more source

BotCl, the First Chlorotoxin-like Peptide Inhibiting Newcastle Disease Virus: The Emergence of a New Scorpion Venom AMPs Family

Molecules, 2023
Newcastle disease virus (NDV) is one of the most serious contagions affecting domestic poultry and other avian species. It causes high morbidity and mortality, resulting in huge economic losses to the poultry industry worldwide.
Abir Jlassi, Marwa Mekni-Toujani, Asma Ferchichi, Charfeddine Gharsallah, Christian Malosse, Julia Chamot-Rooke, Mohamed ElAyeb, Abdeljelil Ghram, Najet Srairi-Abid, Salma Daoud   +9 more
doaj   +1 more source

Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom. [PDF]

Vet Med Sci
The Heteroctenus junceus scorpion venom is a very popular natural extract used in traditional medicine in Cuba. In clinically relevant experimental settings, scorpion venom does not induce general toxicity or an increase in the frequency of micronucleus formation in erythrocytes.
Díaz-García A, Ruiz-Fuentes JL, Mejias Medina S, Zapata Guajardo N, Ross Skarneo C.   +4 more
europepmc   +2 more sources

SdPI, the first functionally characterized Kunitz-type trypsin inhibitor from scorpion venom. [PDF]

PLoS ONE, 2011
BACKGROUND: Kunitz-type venom peptides have been isolated from a wide variety of venomous animals. They usually have protease inhibitory activity or potassium channel blocking activity, which by virtue of the effects on predator animals are essential for
Ruiming Zhao, Hui Dai, Su Qiu, Tian Li, Yawen He, Yibao Ma, Zongyun Chen, Yingliang Wu, Wenxin Li, Zhijian Cao   +9 more
doaj   +1 more source

Mass-Spectrometry-Based Lipidome and Proteome Profiling of Hottentotta saulcyi (Scorpiones: Buthidae) Venom

Toxins, 2022
Scorpion venom is a complex secretory mixture of components with potential biological and physiological properties that attracted many researchers due to promising applications from clinical and pharmacological perspectives.
Parviz Ghezellou, Kevin Jakob, Javad Atashi, Alireza Ghassempour, Bernhard Spengler   +4 more
doaj   +1 more source

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]

Biochem Res Int
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR, Pinos Tamayo EA, Moreira Dos Santos D, Kim B, Almeida JR, Ribeiro RIMA.   +5 more
europepmc   +2 more sources

Inhibitory Effect of Hemiscorpius lepturus Scorpion Venom Fractions on Tachyzoites of Toxoplasma gondii

Iranian Journal of Parasitology, 2022
Background: The present study determined the effect of the fractions obtained from Hemiscorpius lepturus scorpion venom on the tachyzoite of Toxoplasma gondii. Methods: The fractions of dried venom of He.
Lida Khaleghi Rostamkolaie, Hossein Hamidinejat, Mohammad Hossein Razi Jalali, Hossein Najafzadeh Varzi, Massoud Reza Seifi Abadshapouri, Hedieh Jafari   +5 more
doaj   +1 more source