Results 11 to 20 of about 556,612 (159)

Molecular Cloning and Functional Identification of the Antimicrobial Peptide Gene Ctri9594 from the Venom of the Scorpion Chaerilus tricostatus

Antibiotics, 2021
Scorpion venom is a mixture of bioactive peptides, among which neurotoxins and antimicrobial peptides serve especially vital functions. Scorpion venom peptides in Buthidae species have been well described, but toxic peptides from non-Buthidae species ...
Dangui He, Zhijian Cao, Ruhong Zhang, Wenhua Li   +3 more
doaj   +2 more sources

BotCl, the First Chlorotoxin-like Peptide Inhibiting Newcastle Disease Virus: The Emergence of a New Scorpion Venom AMPs Family

Molecules, 2023
Newcastle disease virus (NDV) is one of the most serious contagions affecting domestic poultry and other avian species. It causes high morbidity and mortality, resulting in huge economic losses to the poultry industry worldwide.
Abir Jlassi, Marwa Mekni-Toujani, Asma Ferchichi, Charfeddine Gharsallah, Christian Malosse, Julia Chamot-Rooke, Mohamed ElAyeb, Abdeljelil Ghram, Najet Srairi-Abid, Salma Daoud   +9 more
doaj   +2 more sources

SdPI, the first functionally characterized Kunitz-type trypsin inhibitor from scorpion venom. [PDF]

PLoS ONE, 2011
BACKGROUND: Kunitz-type venom peptides have been isolated from a wide variety of venomous animals. They usually have protease inhibitory activity or potassium channel blocking activity, which by virtue of the effects on predator animals are essential for
Ruiming Zhao, Hui Dai, Su Qiu, Tian Li, Yawen He, Yibao Ma, Zongyun Chen, Yingliang Wu, Wenxin Li, Zhijian Cao   +9 more
doaj   +2 more sources

BmK-YA, an enkephalin-like peptide in scorpion venom. [PDF]

PLoS ONE, 2012
By screening extracts of venom from the Asian scorpion Buthus martensii Karsch (BmK) for their abilities to activate opioid receptors, we have identified BmK-YA, an amidated peptide containing an enkephalin-like sequence. BmK-YA is encoded by a precursor
Yan Zhang, Junyan Xu, Zhiwei Wang, Xiuli Zhang, Xinmiao Liang, Olivier Civelli   +5 more
doaj   +5 more sources

Purification and Characterization of Bot33: A Non-Toxic Peptide from the Venom of Buthus occitanus tunetanus Scorpion [PDF]

Molecules, 2022
Scorpion venom is a rich source of promising therapeutic compounds, such as highly selective ion channel ligands with potent pharmacological effects. Bot33 is a new short polypeptide of 38 amino acid residues with six cysteines purified from the venom of
Rym ElFessi, Oussema Khamessi, Najet Srairi-Abid, Jean-Marc Sabatier, Jan Tytgat, Steve Peigneur, Riadh Kharrat   +6 more
doaj   +2 more sources

Scorpion Venom Heat-Resistant Peptide Protects Transgenic Caenorhabditis elegans from β- Amyloid Toxicity [PDF]

Frontiers in Pharmacology, 2016
Scorpion venom heat-resistant peptide (SVHRP) is a component purified from Buthus martensii Karsch scorpion venom. Our previous studies found SVHRP could enhance neurogenesis and inhibit microglia-mediated neuroinflammation in vivo.
Xiao-Gang Zhang, Xi Wang, Ting-Ting Zhou, Xue-Fei Wu, Yan Peng, Wan-Qin Zhang, Shao Li, Jie Zhao, Jie Zhao   +8 more
doaj   +2 more sources

Unveiling the Diversity and Modifications of Short Peptides in Buthus martensii Scorpion Venom through Liquid Chromatography-High Resolution Mass Spectrometry

Toxins
More recently, short peptides in scorpion venom have received much attention because of their potential for drug discovery. Although various biological effects of these short peptides have been found, their studies have been hindered by the lack of ...
Ling Zeng, Cangman Zhang, Mingrong Yang, Jianfeng Sun, Jingguang Lu, Huixia Zhang, Jianfeng Qin, Wei Zhang, Zhihong Jiang   +8 more
doaj   +2 more sources

Oral Acute Toxicity and Genotoxicity of Heteroctenus junceus Scorpion Venom. [PDF]

Vet Med Sci
The Heteroctenus junceus scorpion venom is a very popular natural extract used in traditional medicine in Cuba. In clinically relevant experimental settings, scorpion venom does not induce general toxicity or an increase in the frequency of micronucleus formation in erythrocytes.
Díaz-García A, Ruiz-Fuentes JL, Mejias Medina S, Zapata Guajardo N, Ross Skarneo C.   +4 more
europepmc   +3 more sources

A Deeper Examination of Thorellius atrox Scorpion Venom Components with Omic Technologies

Toxins, 2017
This communication reports a further examination of venom gland transcripts and venom composition of the Mexican scorpion Thorellius atrox using RNA-seq and tandem mass spectrometry.
Teresa Romero-Gutierrez, Esteban Peguero-Sanchez, Miguel A. Cevallos, Cesar V. F. Batista, Ernesto Ortiz, Lourival D. Possani   +5 more
doaj   +2 more sources

Structural and Functional Elucidation of Peptide Ts11 Shows Evidence of a Novel Subfamily of Scorpion Venom Toxins

Toxins, 2016
To date, several families of peptide toxins specifically interacting with ion channels in scorpion venom have been described. One of these families comprise peptide toxins (called KTxs), known to modulate potassium channels.
Caroline M. Cremonez, Mohitosh Maiti, Steve Peigneur, Juliana Silva Cassoli, Alexandre A. A. Dutra, Etienne Waelkens, Eveline Lescrinier, Piet Herdewijn, Maria Elena de Lima, Adriano M. C. Pimenta, Eliane C. Arantes, Jan Tytgat   +11 more
doaj   +2 more sources