Antimicrobial Activity Developed by Scorpion Venoms and Its Peptide Component
Toxins, 2022 Microbial infections represent a problem of great importance at the public health level, with a high rate of morbidity-mortality worldwide. However, treating the different diseases generated by microorganisms requires a gradual increase in acquired resistance when applying or using them against various antibiotic therapies.
Clara Andrea Rincón-Cortés +3 more
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Molecules, 2022 Scorpion venom is a rich source of promising therapeutic compounds, such as highly selective ion channel ligands with potent pharmacological effects. Bot33 is a new short polypeptide of 38 amino acid residues with six cysteines purified from the venom of
Rym ElFessi +6 more
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Discovery of a New Analgesic Peptide, Leptucin, from the Iranian Scorpion, Hemiscorpius lepturus
Molecules, 2021 Hemiscorpius lepturus scorpion stings do not induce considerable pain based on epidemiological surveys conducted in the southwest part of Iran. Accordingly, this study was aimed to identify the analgesic molecule in H.
Sedigheh Bagheri-Ziari +4 more
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TanP: A Multifunctional Anionic Peptide From Tityus stigmurus Scorpion Venom [PDF]
Frontiers in Molecular Biosciences, 2022 Anionic peptides of scorpions are molecules rich in aspartic and/or glutamic acid residues and correspond to a class of peptides without disulfide bonds that are still little explored. TanP is a linear anionic peptide (50 amino acid residues and net charge −20) present in the venom gland of the scorpion, Tityus stigmurus, with chelating properties for ...
Menilla Maria Alves de Melo +11 more
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Isolation and Purification of a Sodium Channel-Targeting Peptide from Buthotus Schach Scorpion Venom Peptide: Characterization of Hsch1 Toxin [PDF]
Iranian Journal of Chemistry & Chemical EngineeringScorpion venom contains polypeptides that modulate ion channel functions. This study focused on isolating and purifying a novel long-chain peptide targeting the sodium channel from the venom of the Iranian scorpion, Buthotus schach.
Parastoo Lorestanpour +2 more
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Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7. [PDF]
PLoS ONE, 2012 For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed.
Yaoqing Chen +18 more
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Immunomodulatory effect of a purified peptide fraction isolated from Mesobuthus eupeus scorpion venom on astrocytoma cell line (1321N1) [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Objective(s): Multiple Sclerosis is a central nervous system disease which belongs to the category of autoimmune diseases. The prevalence of this disease in Iran is approaching the European level.
bahzad masihipour +3 more
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Antimicrobial peptides from scorpion venoms
Toxicon, 2014 The need for new antimicrobial agents is becoming one of the most urgent requirements in modern medicine. The venoms of many different species are rich sources of biologically active components and various therapeutic agents have been characterized including antimicrobial peptides (AMPs).
Harrison, Patrick L. +3 more
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Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation [PDF]
Frontiers in Pharmacology, 2021 Background: Intervention of neuroinflammation in central nervous system (CNS) represents a potential therapeutic strategy for a host of brain disorders. The scorpion Buthus martensii Karsch (BmK) and its venom have long been used in the Orient to treat inflammation-related diseases such as rhumatoid arthritis and chronic pain.
Xue-Fei Wu +16 more
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Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. [PDF]
PLoS ONE, 2018 Except for the northern region, where the Amazonian black scorpion, T. obscurus, represents the predominant and most medically relevant scorpion species, Tityus serrulatus, the Brazilian yellow scorpion, is widely distributed throughout Brazil, causing ...
Ursula Castro de Oliveira +9 more
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