Results 21 to 30 of about 556,612 (159)

Transcriptomic and Proteomic Analyses Reveal the Diversity of Venom Components from the Vaejovid Scorpion Serradigitus gertschi

Toxins, 2018
To understand the diversity of scorpion venom, RNA from venomous glands from a sawfinger scorpion, Serradigitus gertschi, of the family Vaejovidae, was extracted and used for transcriptomic analysis.
Maria Teresa Romero-Gutiérrez, Carlos Eduardo Santibáñez-López, Juana María Jiménez-Vargas, Cesar Vicente Ferreira Batista, Ernesto Ortiz, Lourival Domingos Possani   +5 more
doaj   +2 more sources

Acetylcholinesterase inhibitory potential of scorpion venom in Aedes aegypti (Diptera: Culicidae) [PDF]

Brazilian Journal of Biology, 2022
Scorpion venom contains a variety of neurotoxins which interact with ion channels and affect their activities. The present study was designed to evaluate the potential of scorpion venom as acetylcholinesterase (AChE) inhibitor by using Aedes aegypti as ...
N. Riaz, F. Zubair, N. Amjad, S. Ashraf, S. Asghar, M. Z. Awan, S. Javaid   +6 more
doaj   +1 more source

Toxinology in the proteomics era: a review on arachnid venom proteomics [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2022
The word venomics was coined to acknowledge the studies that use omics to investigate venom proteins and peptides. Venomics has evolved considerably over the last 20 years. The first works on scorpion or spider venomics were published in the early 2000’s.
Filipi Calbaizer Marchi, Edneia Mendes-Silva, Lucas Rodrigues-Ribeiro, Lucas Gabriel Bolais-Ramos, Thiago Verano-Braga   +4 more
doaj   +1 more source

Mass-Spectrometry-Based Lipidome and Proteome Profiling of Hottentotta saulcyi (Scorpiones: Buthidae) Venom

Toxins, 2022
Scorpion venom is a complex secretory mixture of components with potential biological and physiological properties that attracted many researchers due to promising applications from clinical and pharmacological perspectives.
Parviz Ghezellou, Kevin Jakob, Javad Atashi, Alireza Ghassempour, Bernhard Spengler   +4 more
doaj   +1 more source

Small molecules in the venom of the scorpion Hormurus waigiensis [PDF]

, 2020
Despite scorpion stings posing a significant public health issue in particular regions of the world, certain aspects of scorpion venom chemistry remain poorly described.
Edward R. J. Evans, Lachlan McIntyre, Norelle L. Daly, Wilson, David T., Northfield, Tobin, Tobin D. Northfield, McIntyre, Lachlan, David T. Wilson, Evans, Edward R.J., Daly, Norelle L.   +9 more
core   +1 more source

Inhibitory Effect of Hemiscorpius lepturus Scorpion Venom Fractions on Tachyzoites of Toxoplasma gondii

Iranian Journal of Parasitology, 2022
Background: The present study determined the effect of the fractions obtained from Hemiscorpius lepturus scorpion venom on the tachyzoite of Toxoplasma gondii. Methods: The fractions of dried venom of He.
Lida Khaleghi Rostamkolaie, Hossein Hamidinejat, Mohammad Hossein Razi Jalali, Hossein Najafzadeh Varzi, Massoud Reza Seifi Abadshapouri, Hedieh Jafari   +5 more
doaj   +1 more source

Discovery of a New Analgesic Peptide, Leptucin, from the Iranian Scorpion, Hemiscorpius lepturus

Molecules, 2021
Hemiscorpius lepturus scorpion stings do not induce considerable pain based on epidemiological surveys conducted in the southwest part of Iran. Accordingly, this study was aimed to identify the analgesic molecule in H.
Sedigheh Bagheri-Ziari, Delavar Shahbazzadeh, Soroush Sardari, Jean-Marc Sabatier, Kamran Pooshang Bagheri   +4 more
doaj   +1 more source

Animal Venom Pharmacological Resources: Exploiting Bioactive Peptides to Target Multi-Drug-Resistant Bacteria. [PDF]

Biochem Res Int
Background The escalating rise of multi–drug‐resistant (MDR) bacterial strains significantly threatens global health, creating a “silent pandemic” prompted by natural selection, gene mutation, and horizontal gene transfer. This crisis is worsened by the deficit in the development of new treatments, necessitating the innovative discovery of new potent ...
Jaber R, Mattei C, Accary C, Roufayel R, Abi Khattar Z, Fajloun Z.   +5 more
europepmc   +2 more sources

Isolation and Purification of a Sodium Channel-Targeting Peptide from Buthotus Schach Scorpion Venom Peptide: Characterization of Hsch1 Toxin [PDF]

Iranian Journal of Chemistry & Chemical Engineering
Scorpion venom contains polypeptides that modulate ion channel functions. This study focused on isolating and purifying a novel long-chain peptide targeting the sodium channel from the venom of the Iranian scorpion, Buthotus schach.
Parastoo Lorestanpour, Abdolhassan Doulah, Seyedeh Zeinab Peighambarzadeh   +2 more
doaj   +1 more source

Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of E.coli [PDF]

, 2014
Background: Animal neurotoxin peptides are valuable probes for investigating ion channel structure/function relationships and represent lead compounds for novel therapeutics and insecticides.
Cole, Ambrose R., Lampert, A., Wallace, Bonnie A., O’Reilly, A.O., Lopes, J.L.S.   +4 more
core   +1 more source