Results 41 to 50 of about 556,612 (159)
Toxins, 2016 Scorpion venom is deemed to contain many toxic peptides as an important source of natural compounds. Out of the two hundred proteins identified in Mesobuthus martensii (M. martensii), only a few peptide toxins have been found so far.
Ning Luan +8 more
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SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms. [PDF]
PLoS ONE, 2013 Serine protease inhibitors act as modulators of serine proteases, playing important roles in protecting animal toxin peptides from degradation. However, all known serine protease inhibitors discovered thus far from animal venom belong to the Kunitz-type ...
Zongyun Chen +7 more
doaj +1 more source
Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents. [PDF]
Biochem Res IntGlioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Santiago LR +5 more
europepmc +2 more sources
Molecular Characterization of a Three-disulfide Bridges Beta-like Neurotoxin from Androctonus crassicauda Scorpion Venom [PDF]
Archives of Razi Institute, 2019 Scorpion venom is the richest source of peptide toxins with high levels of specific interactions with different ion-channel membrane proteins. The present study involved the amplification and sequencing of a 310-bp cDNA fragment encoding a beta-like ...
A. Jolodar
doaj +1 more source
Cysteine-free peptides in scorpion venom: geographical distribution, structure-function relationship and mode of action [PDF]
, 2010 Scorpion venoms are well known sources of Na+-channel, K+-channel, Cl--channel, Ca2+-channel and ryanodine channel selective peptides. In 1993, the first cysteine-free peptide was isolated from scorpionvenom.
Du Plessis, L, Du Plessis, J, Elgar, D
core +1 more source
Scorpion venom heat-resistant peptide (SVHRP) enhances neurogenesis and neurite outgrowth of immature neurons in adult mice by up-regulating brain-derived neurotrophic factor (BDNF). [PDF]
PLoS ONE, 2014 Scorpion venom heat-resistant peptide (SVHRP) is a component purified from Buthus martensii Karsch scorpion venom. Although scorpions and their venom have been used in Traditional Chinese Medicine (TCM) to treat chronic neurological disorders, the ...
Tao Wang +12 more
doaj +1 more source
Scorpion Venom: New Promise in the Treatment of Cancer [PDF]
, 2019 Cancer is a public health problem due to its high worldwide morbimortality. Current treatment protocols do not guarantee complete remission, which has prompted to search for new and more effective antitumoral compounds.
Carlos Corredor Pereira +11 more
core +1 more source
Insect Molecular Biology, EarlyView.Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto +2 more
wiley +1 more source
, 2011 International audienceAaCtx is the first chlorotoxin-like peptide isolated from Androctonus australis scorpion venom. Its amino acid sequence shares 70% similarity with chlorotoxin from Leiurus quinquestriatus scorpion venom, from which it differs by ...
Daniel Laffitte +23 more
core +1 more source
Protein and peptide profiles of rats’ organs in scorpion envenomation
Toxicology Reports, 2023 Problem of scorpion envenomation becomes more alarming each year. Main effects of scorpion venom are commonly believed to be related to its neurotoxic properties, yet severe symptoms may also be developed due to the uncontrolled enzymatic activity and ...
Valery Gunas +6 more
doaj +1 more source