new caerin-like antibacterial peptide from the venom gland of the Iranian scorpion Mesobuthus eupeus: cDNA amplification and sequence analysis [PDF]
, 2016 Scorpion venom consists of different types of peptides and proteins which are encoded by individual genes. A full length cDNA consisting of 238 base pair nucleotides and encoding 74 amino acids peptide was isolated from the venom gland of the Iranian ...
Ghasemian, Sepideh +3 more
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Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7. [PDF]
PLoS ONE, 2012 For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed.
Yaoqing Chen +18 more
doaj +1 more source
Immunomodulatory effect of a purified peptide fraction isolated from Mesobuthus eupeus scorpion venom on astrocytoma cell line (1321N1) [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Objective(s): Multiple Sclerosis is a central nervous system disease which belongs to the category of autoimmune diseases. The prevalence of this disease in Iran is approaching the European level.
bahzad masihipour +3 more
doaj +1 more source
Pharmaceutical and Biomedical Research, 2022 Background: The venom peptides from the scorpion fauna of Iran have been poorly characterized so far. Objectives: In this study, we identified a cDNA encoding of an anionic cysteine-free antimicrobial peptide from the Iranian yellow scorpion odontobuthus
Amir Jalali +5 more
doaj
Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. [PDF]
PLoS ONE, 2018 Except for the northern region, where the Amazonian black scorpion, T. obscurus, represents the predominant and most medically relevant scorpion species, Tityus serrulatus, the Brazilian yellow scorpion, is widely distributed throughout Brazil, causing ...
Ursula Castro de Oliveira +9 more
doaj +1 more source
Anticancer Peptides Derived from the Venom of Scorpions Inhabiting Various Biotopes [PDF]
Catrina: The International Journal of Environmental SciencesDespite advances in surgical techniques and adjuvant therapies, the relative prevalence rate of all cancers has risen sharply over the last three decades.
Mariam Gerges +3 more
doaj +1 more source
Therapeutic Potential of Bee and Scorpion Venom Phospholipase A2 (PLA2): A Narrative Review [PDF]
Iranian Journal of Medical Sciences, 2022 Venomous arthropods such as scorpions and bees form one of the important groups with an essential role in medical entomology. Their venom possesses a mixture of diverse compounds, such as peptides, some of which have toxic effects, and enzymatic peptide ...
Parisa Soltan-Alinejad +3 more
doaj +1 more source
, 2021 International audienceButhus occitanus (B. occitanus) is one of the most dangerous scorpions in the world. Despite the involvement of B. occitanus scorpion in severe cases of envenomation in Morocco, no study has focused yet on the proteomic composition ...
Daoudi, Khadija +17 more
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Structure-Activity Relationship of Chlorotoxin-Like Peptides
Toxins, 2016 Animal venom (e.g., scorpion) is a rich source of various protein and peptide toxins with diverse physio-/pharmaco-logical activities, which generally exert their action via target-specific modulation of different ion channel functions.
Syed Abid Ali +6 more
doaj +1 more source
Partial purification of peptides present in the Tityus macrochirus (Buthidae) scorpion venom and preliminary assessment of their cytotoxicity [PDF]
, 2017 Introduction: Scorpion venom contains peptides with neurotoxic action primarily active on ion channels in the nervous system of insects and mammals. They are also characterized as cytolytic and anticancer, biological characteristics that have not yet ...
Vega-Castro, Nohora Angélica +5 more
core +1 more source