Stromal Cell-Derived Factor-1 Promotes Cell Migration, Tumor Growth of Colorectal Metastasis
In a mouse model of established extrahepatic colorectal metastasis, we analyzed whether stromal cellderived factor (SDF) 1 stimulates tumor cell migration in vitro, angiogenesis, tumor growth in vivo.
Otto Kollmar +6 more
doaj +1 more source
We found that SDF-1/CXCR7 axis played an important role in the growth and proliferation of gastric cancer in the previous studies. The objectives of this study were to explore the effects of SDF-1/CXCR7 on the metastatic ability of gastric cancer cells ...
Ameng Shi +4 more
doaj +1 more source
Physiological conditions influencing regenerative potential of stem cells [PDF]
Stem cells are being used in the treatment of cardivovascular diseases. Here, we review the physiologic and pathologic conditions that impact the regenerative potential of stem cells in the treatment of cardiovascular diseases which include the influence
Avitabile, Daniele +3 more
core +1 more source
Spatiotemporal presentation of exogenous SDF-1 with PLGA nanoparticles modulates SDF-1/CXCR4 signaling axis in the rodent cortex [PDF]
Temporal control over SDF-1 releaseviaPLGA nanoparticles differentially affects the SDF-1/CXCR4 signaling axis across the adult cortex.
D. Dutta +5 more
openaire +2 more sources
Metal‐covalent organic frameworks (MCOFs) are novel porous materials that exhibit the advantages of covalent and metal‐organic frameworks. However, it is extremely difficult to resolve their atomic structure and better understand their structure‐properties relation. This work utilizes a synergistic combination of advanced microscopy, spectroscopic, and
Seán Hennessey +11 more
wiley +1 more source
Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML [PDF]
Pharmacological targeting of BTK using ibrutinib has recently shown encouraging clinical activity in a range of lymphoid malignancies. Recently we reported that ibrutinib inhibits human acute myeloid leukemia (AML) blast proliferation and leukemic cell ...
Bowles, Kristian M +6 more
core +2 more sources
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang +13 more
wiley +1 more source
CD26/DPP-4 inhibition recruits regenerative stem cells via stromal cell-derived factor-1 and beneficially influences ischaemia-reperfusion injury in mouse lung transplantation† [PDF]
OBJECTIVES The CD26 antigen is a transmembrane glycoprotein that is constitutively expressed on activated lymphocytes and in pulmonary parenchyma. This molecule is also identified as dipeptidyl peptidase-4 (DPP-4) that cleaves a host of biologically ...
Arni, Stephan +5 more
core
Osteoprotegerin regulates cancer cell migration through SDF-1/CXCR4 axis and promotes tumour development by increasing neovascularization [PDF]
We previously reported that OPG is involved in ischemic tissue neovascularization through the secretion of SDF-1 by pretreated-OPG endothelial colony-forming cells (ECFCs). As the vascularization is one of the key factor influencing the tumour growth and
Benslimane-Ahmim, Z. +7 more
core +2 more sources
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang +4 more
wiley +1 more source

