Results 71 to 80 of about 43,872 (217)
International Journal of Translational MedicineBackground: Active recruitment of osteogenic cells by secreted signaling factors, such as stromal-cell-derived factor 1 (SDF-1), has recently been proposed as a novel strategy to enhance osseointegration.
Vincentius J. Suhardi +4 more
doaj +1 more source
Increased Numbers of CD4+ T‐Cells in the Hypocretin/Orexin Region of Narcolepsy Type 1
Annals of Neurology, EarlyView.Narcolepsy type 1 (NT1) is presumed to be an autoimmune disorder caused by hypothalamic loss of hypocretin (Hcrt; orexin). In postmortem NT1 brains, we observed an 11‐fold increase of CD4+ T‐cells in the Hcrt region compared with control hypothalami, without a corresponding rise in CD8+ T‐cells.
Ling Shan +5 more
wiley +1 more source
Advanced NanoBiomed Research, EarlyView.This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley +1 more source
The Anatomical Record, EarlyView.Abstract Dinosaurs evolved a unique respiratory system with air sacs that contributed to their evolutionary success. Postcranial skeletal pneumaticity (PSP) has been used to infer the presence of air sac systems in some fossil archosaurs. While unambiguous evidence of PSP is well documented in pterosaurs and post‐Carnian saurischians, it remains absent
Tito Aureliano +3 more
wiley +1 more source
Scientific Reports, 2016 Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant carcinoma with an extremely high lethality. We recently reported that hypoxia-inducible factor 1 (HIF-1) targets quiescin sulfhydryl oxidase 1 to facilitate PDAC cell growth and invasion. Here,
Yue Fan +5 more
doaj +1 more source
The Anatomical Record, EarlyView.Abstract The Upper Cretaceous São José do Rio Preto Formation (Bauru Group, southeastern Brazil) has yielded a fragmentary but taxonomically diverse record of titanosaur sauropods, although elements from cervical series remain scarce. Here, we describe a nearly complete sauropod axis from the Vila Ventura Paleontological Area, representing an uncommon ...
Bruno A. Navarro +7 more
wiley +1 more source
Reproductive Medicine and Biology, 2019 Purpose To study the association between stromal cell‐derived factor‐1 (SDF‐1/CXCL12) and vascular endothelial growth factor (VEGF) concentrations in individual human ovarian follicles and IVF outcomes.
Akemi Nishigaki +6 more
doaj +1 more source
Animal Research and One Health, EarlyView.This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu +8 more
wiley +1 more source
Arthritis &Rheumatology, Accepted Article.Objective Osteoarthritis—the leading cause of disability worldwide—disproportionately affects females, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven +6 more
wiley +1 more source
SDF-1 axis and myocardial repair
American Journal of Physiology-Heart and Circulatory Physiology, 2010 the ability of the heart to sustain hemodynamic demands is greatly challenged when cell loss or disruption of myocardial homeostasis occurs. Cell therapy using stem or progenitor cells is a promising option to restore the lost myocardium and normalize ventricular function.
openaire +2 more sources