Ventilator‐Induced Lung Injury: Mechanotransduction and Potential Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.Mechanical ventilation (MV) is expected to undergo significant transformative advancements by 2050, with the emergence of personalized ventilation systems that promise to revolutionize respiratory care. However, the risk of ventilator‐induced lung injury (VILI) remains a significant concern at this stage and VILI still exists at that time.
He Ren +4 more
wiley +1 more source
Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen +5 more
wiley +1 more source
Oligodendrocyte: Development, Plasticity, Biological Functions, Diseases, and Therapeutic Targets
MedComm, Volume 7, Issue 2, February 2026.The oligodendrocyte lineage and its roles in development, plasticity, and CNS homeostasis have been shown to have the potential to treat neurological diseases. However, the main obstacles to clinical translation, particularly in terms of BBB challenges and precise delivery.
Qiong Xiang +6 more
wiley +1 more source
The Role of Glycans in Human Immunity-A Sweet Code. [PDF]
MoleculesTvaroška I.
europepmc +1 more source
Aging of the Hematopoietic System: Mechanisms, Consequences, and Systemic Interactions
Aging Cell, Volume 25, Issue 2, February 2026.Hematopoietic aging arises from intrinsic stem‐cell decline and bone‐marrow niche dysfunction, leading to myeloid skewing, immunosenescence, and clonal hematopoiesis. These changes drive systemic inflammation and multi‐organ disease, which in turn further disrupt the bone‐marrow niche and hematopoietic stem cell (HSC) function, creating a vicious cycle
Masashi Miyawaki +3 more
wiley +1 more source
Targeting immune cell migration as therapy for inflammatory disease: a review. [PDF]
Front ImmunolSong B +5 more
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Biologics to Treat Atopic Dermatitis: Effectiveness, Safety, and Future Directions
Allergy, Volume 81, Issue 2, Page 326-344, February 2026.ABSTRACT Atopic dermatitis (AD) is one of the most common chronic inflammatory skin diseases worldwide. The clinical presentation of AD is heterogeneous and is characterized by a relapsing and remitting course. Most patients suffer from mild AD while approximately 5% to 20% experience severe disease activity, which often requires systemic treatment ...
Marjolein S. de Bruin‐Weller +9 more
wiley +1 more source
Circulating cell adhesion molecules as biomarkers in inflammatory bowel disease: a systematic review and meta-analysis. [PDF]
Front ImmunolPrzęczek K +3 more
europepmc +1 more source
Adhesion molecules in the maternal–fetal interface in healthy pregnancies and preeclampsia
Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 2, Page 298-308, February 2026.This study revealed elevated levels of adhesion molecules in the maternal circulation and reduced levels in the fetal circulation in preeclampsia. The findings suggest systemic maternal endothelial dysfunction in preeclampsia. Lower fetal adhesion molecule levels warrant further study. Abstract Introduction Adhesion molecules are markers of endothelial
Ingrid Kverndalen Frisch +4 more
wiley +1 more source
Drug Management of Inflammatory Bowel Disease (IBD): A Narrative Review. [PDF]
CureusSingh P +7 more
europepmc +1 more source