Results 1 to 10 of about 389 (67)
Frontiers in Plant Science, 2021 Salt stress is an adverse environmental factor for plant growth and development. Under salt stress, plants can activate the selective autophagy pathway to alleviate stress.
Wanlong Su +29 more
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Frontiers in Plant Science, 2014 Cellular homeostasis is essential for the physiology of eukaryotic cells. Eukaryotic cells, including plant cells, utilize two main pathways to adjust the level of cytoplasmic components, namely the proteasomal and the lysosomal/vacuolar pathways ...
Vasko eVeljanovski, Henri eBatoko
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The Selective Autophagy Receptor Optineurin in Crohn’s Disease
Frontiers in Immunology, 2018 Autophagy is a pathway that allows cells to target organelles, protein complexes, or invading microorganisms for lysosomal degradation. The specificity of autophagic processes is becoming increasingly recognized and is conferred by selective autophagy ...
Markus Tschurtschenthaler +2 more
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Targeting Selective Autophagy as a Therapeutic Strategy for Viral Infectious Diseases
Frontiers in Microbiology, 2022 Autophagy is an evolutionarily conserved lysosomal degradation system which can recycle multiple cytoplasmic components under both physiological and stressful conditions.
Yishan Liu +7 more
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Autophagy Reports, 2023 There are two types of autophagy, non-selective (bulk) autophagy, in which substrates are randomly incorporated into autophagosomes, and selective autophagy, in which substrates are specifically targeted.
Takashi Kikuma, Joichiro Nishio
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Selective Autophagy Receptor p62/SQSTM1, a Pivotal Player in Stress and Aging
Frontiers in Cell and Developmental Biology, 2022 Efficient proteostasis is crucial for somatic maintenance, and its decline during aging leads to cellular dysfunction and disease. Selective autophagy is a form of autophagy mediated by receptors that target specific cargoes for degradation and is an ...
Anita V. Kumar +2 more
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Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy. [PDF]
PLoS ONE, 2016 The deposit of polyubiquitinated aggregates has been implicated in the pathophysiology of Parkinson's disease (PD), and growing evidence indicates that selective autophagy plays a critical role in the clearance of ubiquitin-positive protein aggregates by
Sangwook Park +6 more
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Viruses, 2021 Selective autophagy mediates the degradation of cytoplasmic cargos, such as damaged organelles, invading pathogens, and protein aggregates. However, whether it targets double-stranded RNA (dsRNA) of intracellular pathogens is still largely unknown. Here,
Chenyang Xu +5 more
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Autophagy: An Intracellular Degradation Pathway Regulating Plant Survival and Stress Response
Frontiers in Plant Science, 2020 Autophagy is an intracellular process that facilitates the bulk degradation of cytoplasmic materials by the vacuole or lysosome in eukaryotes. This conserved process is achieved through the coordination of different autophagy-related genes (ATGs ...
Tong Su +6 more
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Cellular Physiology and Biochemistry, 2017 Background/Aims: In a previous study, we showed that κ-opioid receptor stimulation with the selective agonist U50,488H ameliorated hypoxic pulmonary hypertension (HPH).
Yaguang Zhou +13 more
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