Results 11 to 20 of about 622,888 (291)
Growing gold nanostructures for shape-selective cellular uptake [PDF]
Nanoscale Research Letters, 2018 With development in the synthesis of shape- and size-dependent gold (Au) nanostructures (NSs) and their applications in nanomedicine, one of the biggest challenges is to understand the interaction of these shapes with cancer cells.
Sulalit Bandyopadhyay +7 more
doaj +6 more sources
Cell-particles interaction – selective uptake and transport of microdiamonds
Communications BiologyDiamond particles have recently emerged as novel agents in cellular studies because of their superb biocompatibility. Their unique characteristics, including small size and the presence of fluorescent color centers, stimulate many important applications.
Armin M. Ebrahimi +3 more
doaj +4 more sources
Selecting Selective Suppressors of Selective Uptake [PDF]
Chemistry & Biology, 2003 Scavenger receptor BI (SR-BI) is a high-density lipoprotein (HDL) receptor that mediates the selective uptake of HDL cholesteryl ester (CE) and the bidirectional flux of free cholesterol (FC). The identification of selective uptake inhibitors holds promise for mechanistic studies of SR-BI and for discovery of pharmaceuticals useful in therapy of ...
openaire +2 more sources
New developments in selective cholesteryl ester uptake [PDF]
Current Opinion in Lipidology, 2013 Selective lipid uptake (SLU) is known to be a major pathway of lipoprotein cholesterol metabolism in experimental animals and humans, but remains poorly understood. This review provides a brief overview of SLU mediated by the HDL receptor scavenger receptor B-type I (SR-BI), and highlights several surprising new findings related to the impact of SLU ...
Jason M, Meyer +2 more
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Scavenger receptor class B type I localizes to a late endosomal compartment
Journal of Lipid Research, 2008 Scavenger receptor class B type I (SR-BI) has an established role in mediating the selective uptake of cholesterol from HDL in hepatocytes, steroidogenic cells, and other tissues.
Malika Ahras, Thet Naing, Ruth McPherson
doaj +1 more source
Female genital disorder as adverse symptom of lamotrigine treatment - A serotoninergic effect? [PDF]
, 1998 The new anticonvulsant, lamotrigine, is becoming an important tool in the treatment of bipolar disorder, including bipolar depression. Its efficacy in bipolar depression might be linked to its inhibition of serotonin uptake.
Amann, Benedikt +2 more
core +1 more source
Effects of amino acid substitutions at glycine 420 on SR-BI cholesterol transport function
Journal of Lipid Research, 2007 Scavenger receptor class B type I (SR-BI) facilitates the uptake of HDL cholesteryl esters (CEs) in a two-step process involving binding of HDL to its extracellular domain and transfer of HDL core CEs to a metabolically active membrane pool, where they ...
Saj Parathath +7 more
doaj +1 more source
Passive water control at the surface of a superhydrophobic lichen [PDF]
, 2011 Some lichens have a super-hydrophobic upper surface, which repels water drops, keeping the surface dry but probably preventing water uptake. Spore ejection requires water and is most efficient just after rainfall.
A Henssen +30 more
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Journal of Lipid Research, 2008 Neutral cholesteryl ester hydrolase (CEH)-mediated hydrolysis of cellular cholesteryl esters (CEs) is required not only to generate free cholesterol (FC) for efflux from macrophages but also to release FC from lipoprotein-delivered CE in the liver for ...
Bin Zhao, Jingmei Song, Shobha Ghosh
doaj +1 more source
Fluoxetine: a case history of its discovery and preclinical development [PDF]
, 2014 Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N +20 more
core +2 more sources