Results 31 to 40 of about 622,888 (291)

Lipoprotein lipase mediates an increase in selective uptake of HDL-associated cholesteryl esters by cells in culture independent of scavenger receptor BI

Journal of Lipid Research, 2001
Scavenger receptor class B type I (SR-BI) mediates the selective uptake of HDL cholesteryl esters (CEs) by the liver. LPL promotes this selective lipid uptake independent of lipolysis.
Franz Rinninger, May Brundert, Ines Brosch, Nicolette Donarski, Ralph M. Budzinski, Heiner Greten   +5 more
doaj   +1 more source

High-capacity selective uptake of cholesteryl ester from native LDL during macrophage foam cell formation

Journal of Lipid Research, 2012
Macrophage foam cells are a defining pathologic feature of atherosclerotic lesions. Recent studies have demonstrated that at high concentrations associated with hypercholesterolemia, native LDL induces macrophage lipid accumulation.
Jason M. Meyer, Ailing Ji, Lei Cai, Deneys R. van der Westhuyzen   +3 more
doaj   +1 more source

Serotonin reuptake inhibitors and cardiovascular disease [PDF]

, 2005
Selective serotonin re-uptake inhibiting drugs (SSRIs) are widely used for endogenous depression. In addition to depleting the nerve terminals of serotonin they also lower blood platelet serotonin levels.
Belcher, P.R., Drake-Holland, A.J., Noble, M.   +2 more
core   +1 more source

Selective gonadotrophin uptake by mouse ovarian carcinoma [PDF]

Experientia, 1972
Bei Mausen mit Granulosa- oder Theca-Tumoren wurde die Bindung von125I-HCG untersucht. Im Vergleich zur Bindung an andere Gewebe derselben Tiere konnte eine zellspezifische Bindung im Bereich der Tumoren festgestellt werden. Die Befunde werden im Zusammenhang mit der Zweizelltheorie der ovariellen Steroidgenese diskutiert.
openaire   +3 more sources

SR-BI Selective Lipid Uptake [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2009
Objective— The purpose of this study was to investigate the interaction of SAA and SR-BI in remodeling of acute phase HDL (AP HDL). Methods and Results— We used SAA and SR-BI adenoviral vector expression models to study the ...
Maria C, de Beer, Nancy R, Webb, Nathan L, Whitaker, Joanne M, Wroblewski, Anisa, Jahangiri, Deneys R, van der Westhuyzen, Frederick C, de Beer   +6 more
openaire   +2 more sources

Implications of endogenous and exogenous lipoprotein lipase for the selective uptake of HDL3-associated cholesteryl esters by mouse peritoneal macrophages

Journal of Lipid Research, 1997
To investigate the implications of endogenous LPL on selective uptake of HDL3-associated cholesteryl esters (HDL3-CEs) by mouse peritoneal macrophages (MPMs), we have performed uptake experiments with MPMs obtained from control mice and transgenic ...
U Panzenboeck, A Wintersberger, S Levak-Frank, R Zimmermann, R Zechner, G M Kostner, E Malle, W Sattler   +7 more
doaj   +1 more source

Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocytes

EJNMMI Research, 2021
Background The therapeutic use of [131I]meta-iodobenzylguanidine ([131I]MIBG) is often accompanied by hematological toxicity, primarily consisting of severe and persistent thrombocytopenia.
Thomas Blom, Rutger Meinsma, Franca di Summa, Emile van den Akker, André B. P. van Kuilenburg, Marten Hansen, Godelieve A. M. Tytgat   +6 more
doaj   +1 more source

Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster [PDF]

, 2004
BACKGROUND: Pancreatic cholesterol esterase has three proposed functions in the intestine: 1) to control the bioavailability of cholesterol from dietary cholesterol esters; 2) to contribute to incorporation of cholesterol into mixed micelles; and 3) to ...
Contos, Linda M, Deck, Lorraine M, Heidrich, John E, Hunsaker, Lucy A, Vander Jagt, David L   +4 more
core   +2 more sources

Role of cholesteryl ester transfer protein in selective uptake of high density lipoprotein cholesteryl esters by adipocytes

Journal of Lipid Research, 2004
Previous reports attributed cholesteryl ester transfer protein (CETP)-mediated HDL cholesteryl ester (CE) selective uptake to the CETP-mediated transfer of CE from HDL to newly secreted apolipoprotein B-containing lipoproteins, which are then ...
Gerard Vassiliou, Ruth McPherson
doaj   +1 more source

Selective uptake of alloxan by pancreatic B-cells [PDF]

Biochemical Journal, 1982
Alloxan rapidly binds to or accumulates in pancreatic B-cells as distinct from non-B-cells. The selective uptake of this cytotoxic agent by the insulin-producing B-cells might account for its well-known diabetogenic effect.
Gorus, Frans K, Malaisse, Willy, Pipeleers, Daniel   +2 more
openaire   +2 more sources