Results 81 to 90 of about 20,702 (201)

Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials

Experimental Physiology, EarlyView.
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler, Pedro Rojas‐Morales, Roman‐Ulrich Müller   +2 more
wiley   +1 more source

Assessment of reagents for selenocysteine conjugation and the stability of selenocysteine adducts [PDF]

Organic & Biomolecular Chemistry, 2016
The allenamide functional group reacts with selenocysteine with notably high efficiency, leads to antibody conjugates with remarkable stability, and shows exquisite selectivity for selenocysteine conjugation.
Lee, Pedzisa, Xiuling, Li, Christoph, Rader, William R, Roush   +3 more
openaire   +2 more sources

Rational Design Strategies for Stimuli‐Responsive DNAzymes Using Modified and Artificial Nucleotides

Chemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
Activity control of RNA‐cleaving DNAzymes in response to external stimuli has attracted growing interest for applications in DNA‐based diagnostics, therapeutics, and dynamic DNA nanotechnology. This review summarizes rational design strategies for stimuli‐responsive DNAzymes using modified or artificial nucleotides, including split and caged DNAzymes ...
Yusuke Takezawa, Mitsuhiko Shionoya
wiley   +1 more source

Biological Chemistry of Hydrogen Selenide

Antioxidants, 2016
There are no two main-group elements that exhibit more similar physical and chemical properties than sulfur and selenium. Nonetheless, Nature has deemed both essential for life and has found a way to exploit the subtle unique properties of selenium to ...
Kellye A. Cupp-Sutton, Michael T. Ashby
doaj   +1 more source

OsPT4 Facilitates Selenomethionine Transport and Biosynthesis to Enhance Seed Accumulation in Rice: Molecular Mechanisms and Biotechnological Potential

Plant Biotechnology Journal, Volume 24, Issue 4, Page 1992-2008, April 2026.
ABSTRACT Selenium (Se) is a vital micronutrient for humans, with important functions for health and anti‐cancer properties. Organic Se shows higher antioxidant activity and much lower toxicity compared to inorganic Se, making it safer for use. Selenomethionine (SeMet) is one of the primary forms of organic Se.
Yang Yang, Lijuan Sun, Jia Wei, Fang Zhang, Shiyan Yang, Jiarui Zhang, Qin Qin, Jun Wang, Guohua Xu, Shubin Sun, Yafei Sun, Yong Xue   +11 more
wiley   +1 more source

Bioinformatic analysis of glutathione peroxidase family from theobroma cacao and gene expression during Moniliophthora perniciosa infection.[Poster-B185] [PDF]

, 2018
Glutathione peroxidases (GPXs) are enzymes which are part of the antioxidant system of the cell. Mammalian GPXs are known as selenoproteins because containing the selenocysteine (Sec) amino acid. In plants, these proteins are less known.
Andrade, Bruno Silva, Martins Alves, Akyla Maria, Micheli, Fabienne, Pereira Menezes, Sara, Peres Gramacho, Karina   +4 more
core  

Foliar Application of Nano‐Selenium Enhances Tea Quality and Selenium Biofortification by Promoting Theanine Synthesis and Nitrogen Metabolism

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2300-2311, April 2026.
ABSTRACT Selenium (Se) biofortification improves crops' nutritional value, while nano‐selenium (nano‐Se) offers enhanced bioavailability over traditional Se fertilisers. The quality of tea (Camellia sinensis) depends critically on nitrogen (N) metabolism and amino acid balance, particularly of theanine.
Qingxue Guo, Zhenghao Wu, Yuxin Xiao, Helena Korpelainen, Chunyang Li   +4 more
wiley   +1 more source

A Versatile Strategy to Reduce UGA-Selenocysteine Recoding Efficiency of the Ribosome Using CRISPR-Cas9-Viral-Like-Particles Targeting Selenocysteine-tRNA^[Ser]Sec Gene

Cells, 2019
The translation of selenoprotein mRNAs involves a non-canonical ribosomal event in which an in-frame UGA is recoded as a selenocysteine (Sec) codon instead of being read as a stop codon.
Caroline Vindry, Olivia Guillin, Philippe E. Mangeot, Théophile Ohlmann, Laurent Chavatte   +4 more
doaj   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, Volume 106, Issue 4, Page 1955-1967, 15 March 2026.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source

Gold–Thiopurine and Thioguanine Platforms for Chemotherapy and Photodynamic Therapy

ChemistryEurope, Volume 4, Issue 3, March 2026.
Gold(I)–thiopurine complexes bearing chromophores and phosphine or N‐heterocyclic carbene ligands were developed as multimodal chemo‐photodynamic agents. They show good stability, moderate lipophilicity, and tunable photoresponse. 6‐TG enhances dark cytotoxicity, 6‐MP improves phototoxicity, and PPh3/NBD provide the most efficient photoactivation ...
Laura Agulló, Juan Carlos Pérez‐Sánchez, María Gil‐Moles, M. Concepción Gimeno   +3 more
wiley   +1 more source